SG11201505192RA - Chromatographic purification of antibodies from chromatin-deficient cell culture harvests - Google Patents

Chromatographic purification of antibodies from chromatin-deficient cell culture harvests

Info

Publication number
SG11201505192RA
SG11201505192RA SG11201505192RA SG11201505192RA SG11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA SG 11201505192R A SG11201505192R A SG 11201505192RA
Authority
SG
Singapore
Prior art keywords
chromatin
antibodies
cell culture
chromatographic purification
deficient cell
Prior art date
Application number
SG11201505192RA
Inventor
Peter Stanley Gagnon
Lee Tze Yang
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201505192RA publication Critical patent/SG11201505192RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/32—Extraction; Separation; Purification by precipitation as complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
SG11201505192RA 2013-02-28 2014-02-27 Chromatographic purification of antibodies from chromatin-deficient cell culture harvests SG11201505192RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361771021P 2013-02-28 2013-02-28
PCT/SG2014/000088 WO2014133459A1 (en) 2013-02-28 2014-02-27 Chromatographic purification of antibodies from chromatin-deficient cell culture harvests

Publications (1)

Publication Number Publication Date
SG11201505192RA true SG11201505192RA (en) 2015-08-28

Family

ID=51428597

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505192RA SG11201505192RA (en) 2013-02-28 2014-02-27 Chromatographic purification of antibodies from chromatin-deficient cell culture harvests

Country Status (7)

Country Link
US (1) US9994611B2 (en)
EP (1) EP2961763A4 (en)
JP (1) JP2016509068A (en)
KR (1) KR20150123796A (en)
CN (1) CN105189530B (en)
SG (1) SG11201505192RA (en)
WO (1) WO2014133459A1 (en)

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FR2902799B1 (en) 2006-06-27 2012-10-26 Millipore Corp METHOD AND UNIT FOR PREPARING A SAMPLE FOR THE MICROBIOLOGICAL ANALYSIS OF A LIQUID
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
CN105037535A (en) 2008-12-16 2015-11-11 Emd密理博公司 Stirred tank reactor and method
KR101551295B1 (en) 2010-05-17 2015-09-08 이엠디 밀리포어 코포레이션 Stimulus responsive polymers for the purification of biomolecules
CN104507955A (en) * 2012-05-31 2015-04-08 新加坡科技研究局 Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities
CN105008383A (en) * 2013-02-26 2015-10-28 新加坡科技研究局 Protein purification in the presence of nonionic organic polymers and electropositive surfaces
JP2016520655A (en) * 2013-06-04 2016-07-14 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ Protein purification process
EP3348565A1 (en) 2014-02-19 2018-07-18 Agency For Science, Technology And Research Fractionation method
US10103547B2 (en) 2014-02-21 2018-10-16 Solarlytics, Inc. Method and system for applying electric fields to multiple solar panels
JP2017506646A (en) * 2014-02-27 2017-03-09 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ Method for reducing the chromatin content of protein preparations by treatment with alkyl cations
JP2019108274A (en) * 2016-04-18 2019-07-04 昭和電工株式会社 Removing method of protein aggregate
CN109311937A (en) * 2016-06-15 2019-02-05 新加坡科技研究局 Method of the enhancing for the chromatographic performance of protein purification
GB201801842D0 (en) * 2018-02-05 2018-03-21 Swedish Biomimetics 3000 Ltd Affinity chromatography
CN111902720A (en) 2018-03-21 2020-11-06 沃特世科技公司 Non-antibody high affinity based sample preparation, adsorbents, devices and methods
HUP1900112A1 (en) 2019-04-04 2020-10-28 Richter Gedeon Nyrt Improvement of affinity chromatography of immunoglobulins by using pre-capture flocculation
JP2023521193A (en) * 2020-04-13 2023-05-23 スリーエム イノベイティブ プロパティズ カンパニー Devices for flow-through processes and purification of target molecules
EP3995196B1 (en) * 2020-11-04 2023-08-09 Sartorius BIA Separations d.o.o. Purification process for lipid-membrane-enclosed complex assemblages
JP2023550799A (en) 2020-11-24 2023-12-05 ザルトリウス ビーアイエー セパレーションズ ディー．オー．オー． Improved cleaning methods for affinity chromatography

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DE59009020D1 (en) 1990-03-22 1995-06-08 Biotest Pharma Gmbh Process for the preparation of an intravenously tolerable immunoglobulin G preparation.
FR2824568B1 (en) * 2001-05-11 2004-04-09 Lab Francais Du Fractionnement PROCESS FOR THE PREPARATION OF HUMAN IMMUNOGLOBULIN CONCENTRATES FOR THERAPEUTIC USE
DE602004006831T2 (en) * 2003-01-09 2008-02-14 Genentech, Inc., South San Francisco CLEANING OF POLYPEPTIDES
US20040260066A1 (en) * 2003-06-20 2004-12-23 De Leon Juan Felipe Method for purifying mixtures of immunoglobulin & albumin
US20070244305A1 (en) * 2004-01-30 2007-10-18 Suomen Punainen Risti Veripalvelu Process for The Manufacture of Virus Safe Immunoglobulin
DK1718675T3 (en) * 2004-02-27 2013-07-15 Octapharma Ag Method of providing a purified virus-safe antibody preparation
EP1786827A4 (en) * 2004-05-14 2008-10-29 Kirin Holdings Kk Methods for immunoglobulin purification
AU2008217189B2 (en) * 2007-02-22 2013-06-13 Baxalta GmbH Method of purification of hydrophobic proteins
JP5713379B2 (en) * 2009-01-15 2015-05-07 株式会社プリベンテック Extraction and purification method of recombinant proteins expressed in recombinant plants and difficult to extract
WO2010151632A1 (en) 2009-06-25 2010-12-29 Bristol-Myers Squibb Company Protein purifacation by caprylic acid (octanoic acid ) precipitation
HUE042314T2 (en) * 2011-02-07 2019-06-28 Cerenis Therapeutics Holding Sa Lipoprotein complexes and manufacturing and uses thereof
EP3210662A1 (en) * 2011-06-08 2017-08-30 Agency For Science, Technology And Research Purification of biological products by constrained cohydration chromatography
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EP3348565A1 (en) 2014-02-19 2018-07-18 Agency For Science, Technology And Research Fractionation method

Also Published As

Publication number Publication date
WO2014133459A1 (en) 2014-09-04
US9994611B2 (en) 2018-06-12
EP2961763A1 (en) 2016-01-06
EP2961763A4 (en) 2016-10-12
JP2016509068A (en) 2016-03-24
KR20150123796A (en) 2015-11-04
CN105189530B (en) 2019-06-07
CN105189530A (en) 2015-12-23
US20160009762A1 (en) 2016-01-14

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