IN2014DN09045A - - Google Patents
Info
- Publication number
- IN2014DN09045A IN2014DN09045A IN9045DEN2014A IN2014DN09045A IN 2014DN09045 A IN2014DN09045 A IN 2014DN09045A IN 9045DEN2014 A IN9045DEN2014 A IN 9045DEN2014A IN 2014DN09045 A IN2014DN09045 A IN 2014DN09045A
- Authority
- IN
- India
- Prior art keywords
- nifedipine
- diuretic
- optionally
- released
- pharmaceutical dosage
- Prior art date
Links
- GHOSNRCGJFBJIB-UHFFFAOYSA-N Candesartan cilexetil Chemical compound C=12N(CC=3C=CC(=CC=3)C=3C(=CC=CC=3)C3=NNN=N3)C(OCC)=NC2=CC=CC=1C(=O)OC(C)OC(=O)OC1CCCCC1 GHOSNRCGJFBJIB-UHFFFAOYSA-N 0.000 abstract 2
- 229960004349 candesartan cilexetil Drugs 0.000 abstract 2
- 239000002934 diuretic Substances 0.000 abstract 2
- 230000001882 diuretic effect Effects 0.000 abstract 2
- 239000002552 dosage form Substances 0.000 abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 2
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 abstract 2
- 229960001597 nifedipine Drugs 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12167035 | 2012-05-07 | ||
| EP13151946 | 2013-01-18 | ||
| PCT/EP2013/059110 WO2013167453A1 (en) | 2012-05-07 | 2013-05-02 | Process for manufacturing a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN09045A true IN2014DN09045A (en, 2012) | 2015-05-22 |
Family
ID=48289160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN9045DEN2014 IN2014DN09045A (en, 2012) | 2012-05-07 | 2013-05-02 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US9539176B2 (en, 2012) |
| EP (1) | EP2846777B1 (en, 2012) |
| JP (1) | JP6231553B2 (en, 2012) |
| KR (1) | KR20150007297A (en, 2012) |
| CN (1) | CN104507459A (en, 2012) |
| AR (1) | AR090940A1 (en, 2012) |
| AU (1) | AU2013258273A1 (en, 2012) |
| BR (1) | BR112014027618A2 (en, 2012) |
| CA (1) | CA2872542A1 (en, 2012) |
| CL (1) | CL2014002988A1 (en, 2012) |
| CO (1) | CO7190241A2 (en, 2012) |
| CR (1) | CR20140511A (en, 2012) |
| DO (1) | DOP2014000251A (en, 2012) |
| EA (1) | EA201492026A1 (en, 2012) |
| EC (1) | ECSP14025965A (en, 2012) |
| ES (1) | ES2612532T3 (en, 2012) |
| GT (1) | GT201400245A (en, 2012) |
| HK (1) | HK1204292A1 (en, 2012) |
| IL (1) | IL235040A0 (en, 2012) |
| IN (1) | IN2014DN09045A (en, 2012) |
| MX (1) | MX2014013320A (en, 2012) |
| PE (1) | PE20142284A1 (en, 2012) |
| PH (1) | PH12014502469A1 (en, 2012) |
| SG (1) | SG11201406363VA (en, 2012) |
| TW (1) | TW201410266A (en, 2012) |
| UY (1) | UY34786A (en, 2012) |
| WO (1) | WO2013167453A1 (en, 2012) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9244004B2 (en) * | 2013-08-08 | 2016-01-26 | Stichting Sron—Netherlands Institute For Space Research | Method and system for inspection of composite assemblies using terahertz radiation |
| US10071482B2 (en) | 2015-08-19 | 2018-09-11 | Ford Global Technologies, Llc | Robotic vehicle painting instrument including a terahertz radiation device |
| US10365229B2 (en) * | 2015-12-31 | 2019-07-30 | Kaiser Optical Systems, Inc. | Real-time characterization of pharmaceutical tablet coatings using Raman spectroscopy |
| DE102016222667A1 (de) * | 2016-11-17 | 2018-05-17 | Robert Bosch Gmbh | Verfahren zum Betrieb einer Anlage zum Herstellen von pharmazeutischen Produkten |
| US10323932B1 (en) | 2017-12-28 | 2019-06-18 | Ford Motor Company | System for inspecting vehicle bodies |
| JP7263047B2 (ja) | 2019-02-25 | 2023-04-24 | 沢井製薬株式会社 | フィルムコーティング錠剤 |
| CN110411978B (zh) * | 2019-07-26 | 2020-05-22 | 中国农业大学 | 一种物料均匀性检测设备及检测方法 |
| CN115192538B (zh) * | 2022-08-02 | 2023-09-15 | 沈阳信康药物研究有限公司 | 一种压制包衣型硝苯地平缓释片及其制备方法 |
Family Cites Families (45)
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|---|---|---|---|---|
| DE1670827C3 (de) | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4426019A (en) | 1981-10-15 | 1984-01-17 | The Coca-Cola Company | Membrane seal and knife combination for a post-mix beverage dispensing system |
| US4576604A (en) | 1983-03-04 | 1986-03-18 | Alza Corporation | Osmotic system with instant drug availability |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| NZ206600A (en) | 1983-05-11 | 1987-01-23 | Alza Corp | Osmotic drug delivery device |
| US5082668A (en) | 1983-05-11 | 1992-01-21 | Alza Corporation | Controlled-release system with constant pushing source |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
| US4948592A (en) | 1986-05-09 | 1990-08-14 | Alza Corporation | Pulsed drug delivery |
| DE3720757A1 (de) | 1987-06-24 | 1989-01-05 | Bayer Ag | Dhp-manteltablette |
| US4931285A (en) | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
| EP0386440B1 (de) | 1989-02-11 | 1992-08-05 | Bayer Ag | Arzneimittel mit kontrollierter Wirkstoffabgabe |
| US5196444A (en) | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| US5656650A (en) | 1990-12-14 | 1997-08-12 | Smithkline Beecham Corp. | Angiotensin II receptor blocking compositions |
| ATE177634T1 (de) | 1990-12-14 | 1999-04-15 | Smithkline Beecham Corp | Angiotensin-ii-rezeptor blockierende zusammensetzungen |
| US5160744A (en) | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
| US5178867A (en) | 1991-08-19 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug in short-time period |
| US5543154A (en) | 1991-12-27 | 1996-08-06 | Merck & Co., Inc. | Controlled release nifedipine delivery device |
| CA2125251C (en) | 1993-06-07 | 2005-04-26 | Yoshiyuki Inada | A pharmaceutical composition for angiotensin ii-mediated diseases |
| DE19747261A1 (de) | 1997-10-25 | 1999-04-29 | Bayer Ag | Osmotisches Arzneimittelfreisetzungssystem |
| EP1191924A4 (en) | 1999-04-06 | 2005-02-09 | Pharmaquest Ltd | PHARMACEUTICAL DOSAGE FORM FOR INTERMITTENT ADMINISTRATION OF (D-THREO) -METHYLPHENIDATE AND A SECOND STIMULANT OF THE CENTRAL NERVOUS SYSTEM |
| US20040115134A1 (en) | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
| US20040219208A1 (en) | 2001-08-03 | 2004-11-04 | Ryu Kawamura | Sustained-release medicines |
| US7413751B2 (en) | 2001-10-25 | 2008-08-19 | Depomed, Inc. | Methods of treatment using a gastric retained losartan dosage |
| US20030161882A1 (en) | 2002-02-01 | 2003-08-28 | Waterman Kenneth C. | Osmotic delivery system |
| AU2003227472A1 (en) | 2002-03-27 | 2003-10-08 | Bayer Aktiengesellschaft | Downsized core tablet containing nifedipine |
| EG24716A (en) | 2002-05-17 | 2010-06-07 | Novartis Ag | Combination of organic compounds |
| US8029822B2 (en) | 2003-05-22 | 2011-10-04 | Osmotica Kereskedelmi és Seolgáltató KFT | Rupturing controlled release device having a preformed passageway |
| AU2003249492A1 (en) | 2003-07-24 | 2005-02-14 | Eswaran Krishnan Iyer | Oral compositions for treatment of diseases |
| WO2005070398A2 (en) | 2004-01-23 | 2005-08-04 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents |
| EP1711168A2 (en) | 2004-01-23 | 2006-10-18 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of candesartan cilexetil |
| WO2005084648A1 (en) | 2004-02-27 | 2005-09-15 | Ranbaxy Laboratories Limited | Pharmaceutical compositions comprising candesartan cilexetil |
| TW200534879A (en) | 2004-03-25 | 2005-11-01 | Bristol Myers Squibb Co | Coated tablet formulation and method |
| TWI415635B (zh) | 2004-05-28 | 2013-11-21 | 必治妥施貴寶公司 | 加衣錠片調製物及製備彼之方法 |
| DE102004062475A1 (de) | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| CA2599415C (en) | 2005-05-10 | 2011-07-19 | Teva Pharmaceutical Industries Ltd. | Stable micronized candesartan cilexetil and methods for preparing thereof |
| DE102005031577A1 (de) | 2005-07-06 | 2007-01-11 | Bayer Healthcare Ag | Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten |
| US8574199B2 (en) | 2006-07-03 | 2013-11-05 | Novo Nordisk A/S | Coupling for injection devices |
| KR100888131B1 (ko) | 2006-10-10 | 2009-03-11 | 한올제약주식회사 | 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제 |
| WO2008045006A1 (en) | 2006-10-11 | 2008-04-17 | Fako Ilaclari A. S. | Formulations of candesartan |
| WO2008065097A2 (en) | 2006-11-28 | 2008-06-05 | Laboratorios Liconsa, S.A. | Stabilized solid pharmaceutical composition of candesartan cilexetil |
| CA2703365A1 (en) | 2007-10-25 | 2009-04-30 | Yuka Yamanouchi | Nifedipine-containing press coated tablet and method of preparing the same |
| DE102008059206A1 (de) * | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
| WO2012031124A2 (en) | 2010-09-03 | 2012-03-08 | Bristol-Myers Squibb Company | Drug formulations using water soluble antioxidants |
-
2013
- 2013-05-02 JP JP2015510742A patent/JP6231553B2/ja not_active Expired - Fee Related
- 2013-05-02 AU AU2013258273A patent/AU2013258273A1/en not_active Abandoned
- 2013-05-02 SG SG11201406363VA patent/SG11201406363VA/en unknown
- 2013-05-02 EP EP13720375.8A patent/EP2846777B1/en not_active Not-in-force
- 2013-05-02 HK HK15104963.8A patent/HK1204292A1/xx unknown
- 2013-05-02 PE PE2014001923A patent/PE20142284A1/es not_active Application Discontinuation
- 2013-05-02 ES ES13720375.8T patent/ES2612532T3/es active Active
- 2013-05-02 WO PCT/EP2013/059110 patent/WO2013167453A1/en active Application Filing
- 2013-05-02 BR BR112014027618A patent/BR112014027618A2/pt not_active IP Right Cessation
- 2013-05-02 CA CA2872542A patent/CA2872542A1/en not_active Abandoned
- 2013-05-02 CN CN201380024042.2A patent/CN104507459A/zh active Pending
- 2013-05-02 KR KR1020147030966A patent/KR20150007297A/ko not_active Withdrawn
- 2013-05-02 EA EA201492026A patent/EA201492026A1/ru unknown
- 2013-05-02 MX MX2014013320A patent/MX2014013320A/es unknown
- 2013-05-02 IN IN9045DEN2014 patent/IN2014DN09045A/en unknown
- 2013-05-03 AR ARP130101527A patent/AR090940A1/es unknown
- 2013-05-06 TW TW102116014A patent/TW201410266A/zh unknown
- 2013-05-06 UY UY0001034786A patent/UY34786A/es not_active Application Discontinuation
- 2013-05-07 US US13/889,100 patent/US9539176B2/en not_active Expired - Fee Related
-
2014
- 2014-10-07 IL IL235040A patent/IL235040A0/en unknown
- 2014-11-04 CL CL2014002988A patent/CL2014002988A1/es unknown
- 2014-11-05 PH PH12014502469A patent/PH12014502469A1/en unknown
- 2014-11-06 EC ECIEPI201425965A patent/ECSP14025965A/es unknown
- 2014-11-06 DO DO2014000251A patent/DOP2014000251A/es unknown
- 2014-11-06 GT GT201400245A patent/GT201400245A/es unknown
- 2014-11-06 CO CO14245829A patent/CO7190241A2/es unknown
- 2014-11-07 CR CR20140511A patent/CR20140511A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20130309302A1 (en) | 2013-11-21 |
| US9539176B2 (en) | 2017-01-10 |
| EP2846777B1 (en) | 2016-10-26 |
| HK1204292A1 (en) | 2015-11-13 |
| MX2014013320A (es) | 2015-08-10 |
| JP2015515999A (ja) | 2015-06-04 |
| TW201410266A (zh) | 2014-03-16 |
| IL235040A0 (en) | 2014-12-31 |
| UY34786A (es) | 2013-11-29 |
| CO7190241A2 (es) | 2015-02-19 |
| AR090940A1 (es) | 2014-12-17 |
| BR112014027618A2 (pt) | 2017-06-27 |
| WO2013167453A1 (en) | 2013-11-14 |
| ECSP14025965A (es) | 2015-12-31 |
| AU2013258273A1 (en) | 2014-11-13 |
| CN104507459A (zh) | 2015-04-08 |
| EP2846777A1 (en) | 2015-03-18 |
| PE20142284A1 (es) | 2014-12-17 |
| CL2014002988A1 (es) | 2015-03-13 |
| CA2872542A1 (en) | 2013-11-14 |
| EA201492026A1 (ru) | 2015-09-30 |
| PH12014502469A1 (en) | 2014-12-22 |
| DOP2014000251A (es) | 2014-12-31 |
| SG11201406363VA (en) | 2014-11-27 |
| JP6231553B2 (ja) | 2017-11-15 |
| KR20150007297A (ko) | 2015-01-20 |
| ES2612532T3 (es) | 2017-05-17 |
| GT201400245A (es) | 2015-08-25 |
| CR20140511A (es) | 2014-12-02 |
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