IN2014DN08199A - - Google Patents

Info

Publication number
IN2014DN08199A
IN2014DN08199A IN8199DEN2014A IN2014DN08199A IN 2014DN08199 A IN2014DN08199 A IN 2014DN08199A IN 8199DEN2014 A IN8199DEN2014 A IN 8199DEN2014A IN 2014DN08199 A IN2014DN08199 A IN 2014DN08199A
Authority
IN
India
Prior art keywords
cxcl13
subject
effective amount
inhibits
activity
Prior art date
Application number
Other languages
English (en)
Inventor
Ernest S Smith
Maurice Zauderer
Original Assignee
Vaccinex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaccinex Inc filed Critical Vaccinex Inc
Publication of IN2014DN08199A publication Critical patent/IN2014DN08199A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IN8199DEN2014 2012-03-02 2013-03-01 IN2014DN08199A (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261606049P 2012-03-02 2012-03-02
PCT/US2013/028602 WO2013130959A1 (en) 2012-03-02 2013-03-01 Methods for the treatment of b cell-mediated inflammatory diseases

Publications (1)

Publication Number Publication Date
IN2014DN08199A true IN2014DN08199A (pl) 2015-05-01

Family

ID=47844534

Family Applications (1)

Application Number Title Priority Date Filing Date
IN8199DEN2014 IN2014DN08199A (pl) 2012-03-02 2013-03-01

Country Status (10)

Country Link
US (1) US9890213B2 (pl)
EP (1) EP2820045B1 (pl)
JP (1) JP6193275B2 (pl)
KR (1) KR102090969B1 (pl)
CN (1) CN104520323B (pl)
AU (1) AU2013225812B2 (pl)
CA (1) CA2865928C (pl)
IN (1) IN2014DN08199A (pl)
NZ (1) NZ629828A (pl)
WO (1) WO2013130959A1 (pl)

Families Citing this family (11)

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MX2011011718A (es) 2009-05-08 2012-01-27 Vaccinex Inc Anticuerpos anti-cd100 y metodos para su uso.
SG188285A1 (en) 2010-09-02 2013-04-30 Vaccinex Inc Anti-cxcl13 antibodies and methods of using the same
DK2766093T3 (en) 2011-10-11 2018-06-06 Vaccinex Inc USE OF SEMAPHORIN-4D BINDING MOLECULES FOR MODULATING THE PERMEABILITY OF THE BLOOD-BRAIN BARRIER
US9708601B2 (en) 2012-04-26 2017-07-18 Vaccinex, Inc. Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
JP6363623B2 (ja) 2013-01-31 2018-07-25 ヴァクシネックス, インコーポレイテッド 免疫グロブリンaのレベルを増大するための方法
DK3013350T3 (da) 2013-06-25 2020-04-14 Vaccinex Inc Anvendelse af semaphorin-4D-hæmmende molekyler i kombination med en immunmodulerende terapi for at hæmme tumorvækst og metastaser
SG11201808554TA (en) 2016-04-22 2018-11-29 Vaccinex Inc Integral membrane protein display on poxvirus extracellular enveloped virions
SG11201900595YA (en) 2016-08-02 2019-02-27 Vaccinex Inc Improved methods for producing polynucleotide libraries in vaccinia virus/eukaryotic cells
PL3328887T3 (pl) * 2016-09-19 2021-12-27 I-Mab Biopharma (Hangzhou) Co., Ltd. Przeciwciała anty-gm-csf i ich zastosowania
KR20210016557A (ko) * 2018-05-31 2021-02-16 글리콤 에이/에스 자가면역 질환 치료를 위한 hmo 혼합물
KR20200106056A (ko) * 2018-09-18 2020-09-10 아이-맵 바이오파마 유에스 리미티드 자가면역 질환 및 암을 치료하기 위한 항-cxcl13 항체

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Also Published As

Publication number Publication date
KR102090969B1 (ko) 2020-03-19
CN104520323B (zh) 2018-05-04
AU2013225812B2 (en) 2017-11-30
KR20140138830A (ko) 2014-12-04
CA2865928A1 (en) 2013-09-06
NZ629828A (en) 2017-05-26
EP2820045B1 (en) 2018-08-22
CN104520323A (zh) 2015-04-15
US20150125467A1 (en) 2015-05-07
AU2013225812A1 (en) 2014-09-25
EP2820045A1 (en) 2015-01-07
US9890213B2 (en) 2018-02-13
CA2865928C (en) 2021-02-16
JP2015509960A (ja) 2015-04-02
WO2013130959A1 (en) 2013-09-06
JP6193275B2 (ja) 2017-09-06

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