IN2014DN07923A - - Google Patents

Info

Publication number
IN2014DN07923A
IN2014DN07923A IN7923DEN2014A IN2014DN07923A IN 2014DN07923 A IN2014DN07923 A IN 2014DN07923A IN 7923DEN2014 A IN7923DEN2014 A IN 7923DEN2014A IN 2014DN07923 A IN2014DN07923 A IN 2014DN07923A
Authority
IN
India
Prior art keywords
present
optically active
bicyclic compound
active bicyclic
enzyme
Prior art date
Application number
Other languages
English (en)
Inventor
Yoshitaka Nakamura
Yukito Furuya
Kousei Shimada
Yoshiyuki Onishi
Original Assignee
Daiichi Sankyo Companyltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Companyltd filed Critical Daiichi Sankyo Companyltd
Publication of IN2014DN07923A publication Critical patent/IN2014DN07923A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/12Formation of amino and carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06Preparation of nitro compounds
    • C07C201/12Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/32Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • C07C45/85Separation; Purification; Stabilisation; Use of additives by treatment giving rise to a chemical modification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/20All rings being cycloaliphatic the ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN7923DEN2014 2012-04-10 2013-04-08 IN2014DN07923A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012089481 2012-04-10
PCT/JP2013/060597 WO2013154066A1 (ja) 2012-04-10 2013-04-08 酵素を用いる二環性化合物の光学分割方法

Publications (1)

Publication Number Publication Date
IN2014DN07923A true IN2014DN07923A (ko) 2015-05-01

Family

ID=49327629

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7923DEN2014 IN2014DN07923A (ko) 2012-04-10 2013-04-08

Country Status (14)

Country Link
US (1) US9394235B2 (ko)
EP (1) EP2837689B1 (ko)
JP (1) JP6023794B2 (ko)
KR (1) KR101976891B1 (ko)
CN (1) CN104245951B (ko)
BR (1) BR112014025158B1 (ko)
CA (1) CA2869994C (ko)
ES (1) ES2624314T3 (ko)
HK (1) HK1205192A1 (ko)
HU (1) HUE033397T2 (ko)
IL (1) IL235002B (ko)
IN (1) IN2014DN07923A (ko)
TW (1) TWI639702B (ko)
WO (1) WO2013154066A1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI635071B (zh) 2013-07-08 2018-09-11 第一三共股份有限公司 光學活性二環γ-胺基酸衍生物及其製造方法
CN107667097B (zh) * 2015-05-27 2021-02-12 诺瓦色生物公司 3-乙基双环[3.2.0]庚-3-烯-6-酮的对映体的分离
CN116903468B (zh) * 2023-07-14 2024-01-26 山东新时代药业有限公司 一种米洛巴林中间体的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60169434A (ja) * 1984-02-14 1985-09-02 Ube Ind Ltd 光学活性なビシクロケトン類の製法
CN1303059C (zh) 1997-10-27 2007-03-07 沃尼尔·朗伯公司 作为药物的环状氨基酸及其衍生物
HN2000000224A (es) 1999-10-20 2001-04-11 Warner Lambert Co Aminoacidos biciclicos como agentes farmaceuticos
TNSN03094A1 (fr) 2001-04-19 2005-12-23 Warner Lambert Co Amino-acides condenses bicycliques ou tricycliques
AU2003248907B2 (en) 2002-07-11 2007-04-26 Merck & Co., Inc. Treatment of neuropathic pain with 6H-pyrrolo[3,4-d]pyridazine compounds
NZ584699A (en) * 2007-09-28 2011-04-29 Daiichi Sankyo Co Ltd Bicyclic gamma-amino acid derivative
WO2010084798A1 (ja) * 2009-01-21 2010-07-29 第一三共株式会社 3環性化合物
JP5557292B2 (ja) 2009-03-26 2014-07-23 第一三共株式会社 二環性γ−アミノ酸誘導体の製造方法
WO2012169474A1 (ja) 2011-06-08 2012-12-13 第一三共株式会社 イミニウム塩を経由する二環性化合物の製造方法
EP2719677B1 (en) * 2011-06-08 2017-09-06 Daiichi Sankyo Company, Limited Method for producing bicyclic compound via claisen rearrangement

Also Published As

Publication number Publication date
IL235002B (en) 2018-04-30
CN104245951B (zh) 2018-08-24
KR20150004804A (ko) 2015-01-13
JPWO2013154066A1 (ja) 2015-12-17
CA2869994C (en) 2017-05-30
BR112014025158A2 (pt) 2017-07-18
JP6023794B2 (ja) 2016-11-09
BR112014025158B1 (pt) 2021-09-21
KR101976891B1 (ko) 2019-05-09
EP2837689B1 (en) 2017-02-15
EP2837689A4 (en) 2015-09-09
EP2837689A1 (en) 2015-02-18
TWI639702B (zh) 2018-11-01
US9394235B2 (en) 2016-07-19
TW201346036A (zh) 2013-11-16
WO2013154066A1 (ja) 2013-10-17
US20150038738A1 (en) 2015-02-05
HK1205192A1 (en) 2015-12-11
HUE033397T2 (en) 2017-12-28
ES2624314T3 (es) 2017-07-13
CN104245951A (zh) 2014-12-24
CA2869994A1 (en) 2013-10-17

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