IN2014DN07531A - - Google Patents

Info

Publication number
IN2014DN07531A
IN2014DN07531A IN7531DEN2014A IN2014DN07531A IN 2014DN07531 A IN2014DN07531 A IN 2014DN07531A IN 7531DEN2014 A IN7531DEN2014 A IN 7531DEN2014A IN 2014DN07531 A IN2014DN07531 A IN 2014DN07531A
Authority
IN
India
Prior art keywords
biological sample
composite image
generating
providing
image
Prior art date
Application number
Other languages
English (en)
Inventor
Antti E Seppo
Fiona Ginty
Kevin B Kenny
David Lavan Henderson
Michael J Gerdes
Moreno Adriana I Larriera
Xiaofeng Liu
Alex D Corwin
Stephen E Zingelewicz
Thomas Ha
Rjun Natalie
Ainura Kyshtoobayeve
Hewgley Denise A Hollman
Ying Li
Original Assignee
Clarient Diagnostic Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clarient Diagnostic Services Inc filed Critical Clarient Diagnostic Services Inc
Publication of IN2014DN07531A publication Critical patent/IN2014DN07531A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
IN7531DEN2014 2012-03-30 2013-03-21 IN2014DN07531A (en, 2012)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261618132P 2012-03-30 2012-03-30
PCT/US2013/033249 WO2013148448A1 (en) 2012-03-30 2013-03-21 Immunoflu0rescence and fluorescent-based nucleic acid analysis on a single sample

Publications (1)

Publication Number Publication Date
IN2014DN07531A true IN2014DN07531A (en, 2012) 2015-04-24

Family

ID=48050953

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7531DEN2014 IN2014DN07531A (en, 2012) 2012-03-30 2013-03-21

Country Status (12)

Country Link
US (2) US20150065371A1 (en, 2012)
EP (1) EP2831591B1 (en, 2012)
JP (1) JP6225163B2 (en, 2012)
KR (1) KR20140142715A (en, 2012)
CN (1) CN104520713A (en, 2012)
AU (1) AU2013240127B2 (en, 2012)
CA (1) CA2867508C (en, 2012)
IN (1) IN2014DN07531A (en, 2012)
NZ (1) NZ630091A (en, 2012)
RU (1) RU2014137129A (en, 2012)
SG (1) SG11201406105UA (en, 2012)
WO (1) WO2013148448A1 (en, 2012)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
EP4148118A1 (en) 2012-08-24 2023-03-15 Yale University System, device and method for high-throughput multi-plexed detection
US10088658B2 (en) 2013-03-18 2018-10-02 General Electric Company Referencing in multi-acquisition slide imaging
DK3111221T4 (da) 2014-02-24 2022-04-19 Ventana Med Syst Inc Fremgangsmåder, kit og systemer til scoring af immunresponsen mod cancer ved samtidig påvisning af CD3, CD8, CD20 og FOXP3
CN104980558B (zh) * 2014-04-01 2019-01-01 中国移动通信集团公司 一种信息处理的方法、装置、手机宠物客户端及移动终端
US20150286887A1 (en) * 2014-04-07 2015-10-08 Massachusetts Institute Of Technology Use of Microparticle Additives to Simultaneously Enable Artifact-Free Image Registration, Auto-Focusing, and Chromatic Aberration Correction in Microscopy
JP2017526011A (ja) * 2014-08-18 2017-09-07 ビューズアイキュウ インコーポレイテッド 広視野顕微鏡スキャンにおける埋め込み画像のためのシステムおよび方法
CN107407638B (zh) 2014-12-03 2021-01-12 伊索普莱西斯公司 细胞分泌特征的分析和筛选
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
US10706536B2 (en) * 2015-07-20 2020-07-07 Min Xu Photon structure and chemometrics pathologic system
US10748283B2 (en) 2015-12-24 2020-08-18 Konica Minolta, Inc. Image processing device and program
CN107419001A (zh) * 2016-05-23 2017-12-01 益善生物技术股份有限公司 Brca1、pten基因异常检测试剂盒及检测方法
JP6231709B1 (ja) * 2016-05-31 2017-11-15 シスメックス株式会社 蛍光画像分析装置および分析方法
JP6755975B2 (ja) * 2016-06-10 2020-09-16 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 明視野像シミュレーションのためのシステム
CN106290878A (zh) * 2016-09-10 2017-01-04 天津大学 基于量子点的胰腺癌肿瘤标志物ca242免疫层析试纸条的制备方法
EP3510398A1 (en) 2016-09-12 2019-07-17 Isoplexis Corporation System and methods for multiplexed analysis of cellular and other immunotherapeutics
ES2961743T3 (es) * 2016-09-26 2024-03-13 Becton Dickinson Co Medición de la expresión de proteínas utilizando reactivos con secuencias de oligonucleótidos con código de barras
CN110199196B (zh) 2016-11-11 2022-09-30 伊索普莱克西斯公司 用于单细胞的同时基因组,转录本和蛋白质组分析的组合物和方法
WO2018098372A1 (en) 2016-11-22 2018-05-31 IsoPlexis Corporation Systems, devices and methods for cell capture and methods of manufacture thereof
JP7116175B2 (ja) * 2018-08-22 2022-08-09 オリンパス株式会社 画像処理装置、撮像システム、画像処理装置の作動方法、及び画像処理装置の作動プログラム
US10921223B2 (en) * 2018-10-12 2021-02-16 Shenzhen Prs Limited Process record slide for staining and method of using the same
CN110498858B (zh) * 2019-07-26 2024-01-23 深圳市达科为生物工程有限公司 一种动态检测单细胞外泌蛋白分泌情况的方法
US11630067B2 (en) * 2019-12-17 2023-04-18 Applied Materials, Inc. System for acquisition and processing of multiplexed fluorescence in-situ hybridization images
WO2021226311A1 (en) * 2020-05-07 2021-11-11 Advanced Cell Diagnostics, Inc. Methods for simultaneously detecting target nucleic acids and proteins and a kit thereof
CN116075724A (zh) * 2020-07-20 2023-05-05 阿科亚生物科学股份有限公司 处理和成像组织样品
CN116113983A (zh) * 2020-08-13 2023-05-12 文塔纳医疗系统公司 多重免疫荧光染色组织的数字图像中坏死区域的自动化识别
AU2021345283B2 (en) * 2020-09-18 2024-12-19 10X Genomics, Inc. Sample handling apparatus and image registration methods
CN112415198B (zh) * 2020-11-20 2022-11-11 四川大学华西医院 Gp1bb检测试剂在制备肺癌筛查试剂盒中的用途
CN113310963B (zh) * 2021-05-31 2023-12-01 四川大学华西医院 一种改进的中性粒细胞NETs免疫荧光检测方法
IL312540A (en) 2021-11-16 2024-07-01 Sotio Biotech Inc Treatment of myxoid/round cell liposarcoma patients
WO2023147133A1 (en) * 2022-01-28 2023-08-03 University Of Southern California Liquid biopsy analytes to define cancer stages
EP4469788A1 (en) * 2022-01-28 2024-12-04 The University Of Southern California Identifying non-disease patients using a disease related assay and analysis in the liquid biopsy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6404906B2 (en) 1997-03-03 2002-06-11 Bacus Research Laboratories,Inc. Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
US7629125B2 (en) * 2006-11-16 2009-12-08 General Electric Company Sequential analysis of biological samples
US20110189670A1 (en) * 2008-07-07 2011-08-04 Ruth L Katz Circulating Tumor and Tumor Stem Cell Detection Using Genomic Specific Probes
US8269827B2 (en) * 2009-09-29 2012-09-18 General Electric Company System and methods for mapping fluorescent images into a bright field color space

Also Published As

Publication number Publication date
CA2867508C (en) 2021-05-18
RU2014137129A (ru) 2016-05-27
EP2831591A1 (en) 2015-02-04
KR20140142715A (ko) 2014-12-12
AU2013240127A1 (en) 2014-10-02
CA2867508A1 (en) 2013-10-03
US20150065371A1 (en) 2015-03-05
WO2013148448A1 (en) 2013-10-03
EP2831591B1 (en) 2019-05-08
AU2013240127B2 (en) 2018-07-12
CN104520713A (zh) 2015-04-15
JP6225163B2 (ja) 2017-11-01
US20250102507A1 (en) 2025-03-27
SG11201406105UA (en) 2014-10-30
NZ630091A (en) 2016-03-31
JP2015514212A (ja) 2015-05-18

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