IN2014DN06132A - - Google Patents
Info
- Publication number
- IN2014DN06132A IN2014DN06132A IN6132DEN2014A IN2014DN06132A IN 2014DN06132 A IN2014DN06132 A IN 2014DN06132A IN 6132DEN2014 A IN6132DEN2014 A IN 6132DEN2014A IN 2014DN06132 A IN2014DN06132 A IN 2014DN06132A
- Authority
- IN
- India
- Prior art keywords
- formula
- pharmaceutical composition
- administering
- subject
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261586450P | 2012-01-13 | 2012-01-13 | |
US201261622627P | 2012-04-11 | 2012-04-11 | |
PCT/US2013/021245 WO2013106717A1 (en) | 2012-01-13 | 2013-01-11 | Anesthetic compounds and related methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN06132A true IN2014DN06132A (pt) | 2015-08-14 |
Family
ID=48781947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN6132DEN2014 IN2014DN06132A (pt) | 2012-01-13 | 2013-01-11 |
Country Status (23)
Country | Link |
---|---|
US (4) | US9156825B2 (pt) |
EP (2) | EP2802325B1 (pt) |
JP (1) | JP6196986B2 (pt) |
CN (2) | CN107382812A (pt) |
AU (1) | AU2013207811B2 (pt) |
BR (1) | BR112014017230A2 (pt) |
CA (1) | CA2861071C (pt) |
CY (1) | CY1118842T1 (pt) |
DK (1) | DK2802325T3 (pt) |
EA (1) | EA027976B1 (pt) |
ES (1) | ES2617536T3 (pt) |
HR (1) | HRP20170330T1 (pt) |
HU (1) | HUE030892T2 (pt) |
IN (1) | IN2014DN06132A (pt) |
LT (1) | LT2802325T (pt) |
NZ (1) | NZ627274A (pt) |
PL (1) | PL2802325T3 (pt) |
PT (1) | PT2802325T (pt) |
RS (1) | RS56025B1 (pt) |
SG (1) | SG11201403980VA (pt) |
SI (1) | SI2802325T1 (pt) |
WO (1) | WO2013106717A1 (pt) |
ZA (1) | ZA201405248B (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE058909T2 (hu) * | 2015-10-10 | 2022-09-28 | Jiangsu Nhwaluokang Pharmceutical Res And Development Co Ltd | Etomidátszármazék és köztitermék, eljárás elõállítására és alkalmazása |
CN105663042A (zh) * | 2016-02-03 | 2016-06-15 | 北京蓝丹医药科技有限公司 | 一种稳定的麻醉药物脂肪乳及其制备方法 |
CN107382870A (zh) * | 2016-05-17 | 2017-11-24 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN107445898A (zh) * | 2016-05-30 | 2017-12-08 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN107522662A (zh) * | 2016-06-16 | 2017-12-29 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN107641105A (zh) * | 2016-07-22 | 2018-01-30 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN106432163A (zh) * | 2016-09-29 | 2017-02-22 | 山东东方农药科技实业有限公司 | 一种螺环内酯类化合物、其合成方法以及其用途 |
CN107652239B (zh) * | 2017-02-24 | 2020-08-04 | 四川大学华西医院 | N-取代咪唑羧酸酯类化合物、制备方法及用途 |
CN109776512A (zh) * | 2018-01-30 | 2019-05-21 | 成都安诺晨创医药科技有限公司 | 一种n-取代咪唑甲酸酯类衍生物及其用途 |
CN109053410A (zh) * | 2018-08-06 | 2018-12-21 | 兰博尔开封科技有限公司 | 一种合成1-羟基环己基甲酸的新工艺及应用 |
CN112512591B (zh) | 2018-09-26 | 2024-08-16 | 江苏恒瑞医药股份有限公司 | 依喜替康类似物的配体-药物偶联物及其制备方法和应用 |
EP3854816A4 (en) | 2018-09-30 | 2022-09-07 | Jiangsu Hengrui Medicine Co., Ltd. | EXATECAN ANTI-B7H3-ANALOG ANTIBODY CONJUGATE AND ASSOCIATED MEDICAL USE |
CN109761906B (zh) * | 2019-03-02 | 2023-08-11 | 成都麻沸散医药科技有限公司 | 一种取代咪唑甲酸酯类衍生物及其用途 |
CN110003188B (zh) * | 2019-03-27 | 2022-08-26 | 成都麻沸散医药科技有限公司 | 取代吡咯甲酸酯类衍生物及其用途 |
EP4032892A4 (en) | 2019-09-18 | 2023-10-18 | Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. | CAMPTOTHECIN DERIVATIVE AND CONJUGATE THEREOF |
CN110669017B (zh) * | 2019-10-11 | 2023-08-04 | 成都麻沸散医药科技有限公司 | 多取代三唑甲酸酯类衍生物及其用途 |
CN112174890B (zh) * | 2020-10-09 | 2022-05-27 | 成都麻沸散医药科技有限公司 | 酮取代杂环化合物及其麻醉作用 |
WO2021068943A1 (zh) * | 2019-10-11 | 2021-04-15 | 成都麻沸散医药科技有限公司 | 一种取代氮杂环化合物及其麻醉作用 |
TW202128227A (zh) | 2019-12-12 | 2021-08-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗密蛋白抗體藥物偶聯物及其醫藥用途 |
EP4079761A4 (en) | 2019-12-16 | 2024-02-07 | Jiangsu Hengrui Medicine Co., Ltd. | ANTI-CEA ANTIBODIES EXATECAN ANALOG CONJUGATE AND ITS PHARMACEUTICAL USE |
AU2021210074A1 (en) | 2020-01-22 | 2022-07-28 | Jiangsu Hengrui Medicine Co., Ltd. | Anti-TROP-2 antibody-exatecan analog conjugate and medical use thereof |
CA3168654A1 (en) | 2020-01-22 | 2021-07-29 | Shanghai Senhui Medicine Co., Ltd. | Drug conjugate of eribulin derivative, preparation method therefor and application thereof in medicine |
AU2021243080A1 (en) | 2020-03-25 | 2022-09-22 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Preparation method for antibody medicament conjugate |
MX2022011808A (es) | 2020-03-25 | 2022-12-06 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Conjugado de anticuerpo anti-psma-analogo de exatecan y uso medico del mismo. |
EP4129345A4 (en) | 2020-03-25 | 2023-11-29 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | PHARMACEUTICAL COMPOSITION COMPRISING AN ANTIBODY-DRUG CONJUGATE AND USE THEREOF |
MX2024000893A (es) | 2021-07-22 | 2024-02-06 | Shanghai Senhui Medicine Co Ltd | Farmaco conjugado de un derivado de eribulina. |
WO2023116861A1 (zh) | 2021-12-23 | 2023-06-29 | 江苏恒瑞医药股份有限公司 | 抗dll3抗体、其抗体-药物偶联物及其医药用途 |
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US3354173A (en) | 1964-04-16 | 1967-11-21 | Janssen Pharmaceutica Nv | Imidazole carboxylates |
US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
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GR64915B (en) | 1978-09-14 | 1980-06-09 | Janssen Pharmaceutica Nv | Improved etomidate-containing compositions |
EP0277384A3 (en) | 1986-12-24 | 1990-05-23 | Janssen Pharmaceutica N.V. | 1h-imidazole-5-carboxylic acid derivatives |
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ZA90554B (en) | 1989-01-31 | 1990-10-31 | Merrell Pharma Inc | Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions |
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JPH06345728A (ja) | 1993-06-11 | 1994-12-20 | Nissan Chem Ind Ltd | N−置換アゾール誘導体の製造方法 |
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US20080206138A1 (en) | 2003-08-06 | 2008-08-28 | Ilse Zolle | Radiolabelled Phenylethyl Imidazole Carboxylic Acid Ester Derivatives |
US7189859B2 (en) | 2003-08-06 | 2007-03-13 | Ilse Zolle | Radiolabelled phenylethyl imidazole carboxylic acid ester derivatives |
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US8071785B2 (en) | 2006-06-09 | 2011-12-06 | Ge Healthcare Limited | Synthesis and evaluation of 18F-labelled-alkyl-1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate as a tracer for the quantification of β-11-hydroxylase enzyme in the adrenal glands |
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2013
- 2013-01-11 DK DK13735638.2T patent/DK2802325T3/en active
- 2013-01-11 PL PL13735638T patent/PL2802325T3/pl unknown
- 2013-01-11 SG SG11201403980VA patent/SG11201403980VA/en unknown
- 2013-01-11 IN IN6132DEN2014 patent/IN2014DN06132A/en unknown
- 2013-01-11 CN CN201710140475.4A patent/CN107382812A/zh active Pending
- 2013-01-11 EP EP13735638.2A patent/EP2802325B1/en active Active
- 2013-01-11 ES ES13735638.2T patent/ES2617536T3/es active Active
- 2013-01-11 NZ NZ627274A patent/NZ627274A/en not_active IP Right Cessation
- 2013-01-11 AU AU2013207811A patent/AU2013207811B2/en active Active
- 2013-01-11 BR BR112014017230-7A patent/BR112014017230A2/pt not_active IP Right Cessation
- 2013-01-11 JP JP2014552332A patent/JP6196986B2/ja active Active
- 2013-01-11 HU HUE13735638A patent/HUE030892T2/hu unknown
- 2013-01-11 WO PCT/US2013/021245 patent/WO2013106717A1/en active Application Filing
- 2013-01-11 CA CA2861071A patent/CA2861071C/en active Active
- 2013-01-11 CN CN201380014062.1A patent/CN104168899B/zh active Active
- 2013-01-11 US US14/371,651 patent/US9156825B2/en active Active
- 2013-01-11 LT LTEP13735638.2T patent/LT2802325T/lt unknown
- 2013-01-11 RS RS20170208A patent/RS56025B1/sr unknown
- 2013-01-11 PT PT137356382T patent/PT2802325T/pt unknown
- 2013-01-11 SI SI201330552A patent/SI2802325T1/sl unknown
- 2013-01-11 EA EA201491362A patent/EA027976B1/ru not_active IP Right Cessation
- 2013-01-11 EP EP16198942.1A patent/EP3184512B1/en active Active
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2014
- 2014-07-17 ZA ZA2014/05248A patent/ZA201405248B/en unknown
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2015
- 2015-07-24 US US14/808,413 patent/US9522136B2/en active Active
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2016
- 2016-11-10 US US15/348,790 patent/US9820971B2/en active Active
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2017
- 2017-02-24 CY CY20171100255T patent/CY1118842T1/el unknown
- 2017-02-27 HR HRP20170330TT patent/HRP20170330T1/hr unknown
- 2017-10-19 US US15/788,351 patent/US10154991B2/en active Active
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