IN2014DN04645A - - Google Patents

Info

Publication number
IN2014DN04645A
IN2014DN04645A IN4645DEN2014A IN2014DN04645A IN 2014DN04645 A IN2014DN04645 A IN 2014DN04645A IN 4645DEN2014 A IN4645DEN2014 A IN 4645DEN2014A IN 2014DN04645 A IN2014DN04645 A IN 2014DN04645A
Authority
IN
India
Prior art keywords
mediator
probe
region
relates
detecting
Prior art date
Application number
Other languages
English (en)
Inventor
Günter Roth
Bernd Faltin
Stetten Felix Von
Simon Wadle
Original Assignee
Albert Ludwigs Universität Freiburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albert Ludwigs Universität Freiburg filed Critical Albert Ludwigs Universität Freiburg
Publication of IN2014DN04645A publication Critical patent/IN2014DN04645A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6823Release of bound markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
IN4645DEN2014 2011-11-10 2012-11-12 IN2014DN04645A (enrdf_load_stackoverflow)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102011055247A DE102011055247A1 (de) 2011-11-10 2011-11-10 Multianalyt-Reportersystem
PCT/EP2012/072402 WO2013079307A1 (de) 2011-11-10 2012-11-12 Bifunktionale oligonukleotidsonde zur universellen echtzeit multianalytdetektion

Publications (1)

Publication Number Publication Date
IN2014DN04645A true IN2014DN04645A (enrdf_load_stackoverflow) 2015-05-08

Family

ID=47324049

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4645DEN2014 IN2014DN04645A (enrdf_load_stackoverflow) 2011-11-10 2012-11-12

Country Status (9)

Country Link
US (1) US11293053B2 (enrdf_load_stackoverflow)
EP (1) EP2776585B8 (enrdf_load_stackoverflow)
JP (1) JP6265905B2 (enrdf_load_stackoverflow)
CN (1) CN103946397B (enrdf_load_stackoverflow)
CA (1) CA2854427A1 (enrdf_load_stackoverflow)
DE (1) DE102011055247A1 (enrdf_load_stackoverflow)
ES (1) ES2698903T3 (enrdf_load_stackoverflow)
IN (1) IN2014DN04645A (enrdf_load_stackoverflow)
WO (1) WO2013079307A1 (enrdf_load_stackoverflow)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012100824A1 (de) 2012-02-01 2013-09-05 Albert-Ludwigs-Universität Freiburg Gemultiplexte Digital PCR
CA2904545A1 (en) * 2012-03-20 2013-09-26 Universite Laval A nucleic acid detection method comprising target specific indexing probes (tsip) comprising a releasable segment to be detected via fluorescence when bound to a capture probe
US20140272959A1 (en) * 2013-03-14 2014-09-18 President And Fellows Of Harvard College Methods of Hybridizing Probes to Genomic DNA
US20140378327A1 (en) * 2013-06-19 2014-12-25 Luminex Corporation Real-time multiplexed hydrolysis probe assay using spectrally identifiable microspheres
EP3034619B1 (de) * 2014-12-16 2018-10-17 microBIOMix GmbH Modifizierte Oligonukleotide und Verfahren zum Einschleusen von Primern oder Kontrollmolekülen oder Sonden in geschlossene PCR-Systeme
WO2016134191A1 (en) * 2015-02-18 2016-08-25 Singular Bio, Inc. Assays for single molecule detection and use thereof
KR101875662B1 (ko) * 2015-12-01 2018-08-02 에스디 바이오센서 주식회사 등온 핵산 증폭을 위한 리포터 염료, 퀀처가 포함되는 등온 기반 이중 기능성 올리고뉴클레오타이드 및 이를 이용한 핵산 증폭과 측정 방법
CN107024583B (zh) * 2016-01-29 2019-03-08 中国科学院苏州纳米技术与纳米仿生研究所 硫黄素t适配体、其筛选方法及应用
US20190376126A1 (en) * 2016-12-23 2019-12-12 Albert-Ludwigs-Universität Freiburg Two-part mediator probe
CN108823287B (zh) 2017-04-28 2019-04-12 厦门大学 一种检测靶核酸序列的方法
GB201713251D0 (en) * 2017-08-18 2017-10-04 Lgc Genomics Ltd Methods and kits for detection of nucleic acid molecules
CN111100935B (zh) * 2018-10-26 2023-03-31 厦门大学 一种细菌耐药基因检测的方法
EP4237584B1 (en) * 2020-10-29 2025-04-23 Biocartis NV Generic cartridge and method for multiplex nucleic acid detection
CN116356075A (zh) * 2021-12-27 2023-06-30 迈克生物股份有限公司 一种用于检测的引物探针、引物探针组及其应用
EP4265735A1 (de) 2022-04-22 2023-10-25 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Pcr-multiplexing durch zielsequenz-unabhängige-reportermoleküle mit unterscheid-baren signalstäken
WO2023203230A1 (de) 2022-04-22 2023-10-26 Hahn-Schickard-Gesellschaft Für Angewandte Forschung E. V. Nukleinsäurenachweis in einer pcr mittels eines zielsequenz-unspezifischem modularer reporterkomplexes
EP4265734A1 (de) 2022-04-22 2023-10-25 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Nukleinsäurenachweis in einer pcr mittels eines zielsequenz-unspezifischem modularer reporterkomplexes
JP2025513429A (ja) 2022-04-22 2025-04-24 ハーン-シカード-ゲゼルシャフト フォー アングワント フォースクング イー.ブイ. 区別可能なシグナルの強さを有する標的配列非依存性レポーター分子によるpcr多重化
EP4372100A1 (en) 2022-11-15 2024-05-22 Stilla Technologies Data analysis method for multiplex digital pcr using color-combination
WO2025026366A1 (en) * 2023-07-31 2025-02-06 Coyote Bioscience Co., Ltd. Compositions and methods for nucleic acid detection
CN117144067A (zh) * 2023-10-31 2023-12-01 中国医学科学院北京协和医院 用于多重化核酸检测的组合物和方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751177A (en) * 1985-06-13 1988-06-14 Amgen Methods and kits for performing nucleic acid hybridization assays
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
US6099803A (en) 1994-07-07 2000-08-08 Nanogen, Inc. Advanced active electronic devices for molecular biological analysis and diagnostics
US5641658A (en) 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
GB9615516D0 (en) * 1996-07-24 1996-09-04 Jsd Tech Ltd Bacillus cereus
WO2000042209A1 (en) 1999-01-15 2000-07-20 Ljl Biosystems, Inc. Methods and apparatus for detecting polynucleotide hybridization
US6238869B1 (en) 1997-12-19 2001-05-29 High Throughput Genomics, Inc. High throughput assay system
US6300070B1 (en) 1999-06-04 2001-10-09 Mosaic Technologies, Inc. Solid phase methods for amplifying multiple nucleic acids
DE60040335D1 (de) * 1999-07-14 2008-11-06 Packard Bioscience Co Derivatisierte nukleinsäuren und deren verwendung
US6380377B1 (en) * 2000-07-14 2002-04-30 Applied Gene Technologies, Inc. Nucleic acid hairpin probes and uses thereof
DE60131903T2 (de) * 2000-10-24 2008-11-27 The Board of Trustees of the Leland S. Stanford Junior University, Palo Alto Direkte multiplex charakterisierung von genomischer dna
CA2473865A1 (en) * 2002-02-06 2003-08-14 Amersham Biosciences Ab Compositions and methods for rolling circle amplification
GB0230238D0 (en) * 2002-12-28 2003-02-05 Fu Guoliang Combined exponential and linear amplification
DE10316159A1 (de) 2003-04-09 2004-10-28 Klapproth, Holger, Dr. 5`-3`-Exonuklease Assay zur Bestimmung der Konzentration von Nukleinsäuren
JP5520449B2 (ja) 2007-03-06 2014-06-11 株式会社ビー・エム・エル 核酸の検出方法
WO2009117327A2 (en) * 2008-03-15 2009-09-24 Hologic, Inc. Compositions and methods for analysis of nucleic acid molecules during amplification reactions
WO2012096430A1 (en) 2011-01-11 2012-07-19 Seegene, Inc. Detection of target nucleic acid sequences by pto cleavage and extension assay

Also Published As

Publication number Publication date
ES2698903T3 (es) 2019-02-06
JP6265905B2 (ja) 2018-01-24
EP2776585B1 (de) 2018-08-22
CA2854427A1 (en) 2013-06-06
WO2013079307A1 (de) 2013-06-06
EP2776585A1 (de) 2014-09-17
US11293053B2 (en) 2022-04-05
JP2014533107A (ja) 2014-12-11
EP2776585B8 (de) 2019-04-10
CN103946397B (zh) 2021-03-16
CN103946397A (zh) 2014-07-23
DE102011055247A1 (de) 2013-05-16
US20140315747A1 (en) 2014-10-23

Similar Documents

Publication Publication Date Title
IN2014DN04645A (enrdf_load_stackoverflow)
MX364410B (es) Metodo para detectar nucleosomas que contienen nucleotidos.
FR2979736B1 (fr) Procede de detection de messages sia
NZ776663A (en) Detection of chromosome interactions
ZA201403260B (en) Method for detecting nucleosome adducts
EP3425063C0 (en) PROCEDURE FOR DETECTING ANALYTES
IL228857B (en) Method and system for target detection
EP2676122A4 (en) AMPEROMETRIC SENSOR SYSTEM
EP2680744A4 (en) SENSOR SYSTEM FOR PATIENT BEDS
DE102012208877A8 (de) System zur Erfassung bewegter Objekte
IL227865A0 (en) Quantitative, highly multiplexed detection of nucleic acids
GB201200658D0 (en) Methods,compositions,and kits for determining the presence/absence of a variant nucleic acid sequence
IL230610A0 (en) Methods for detecting nucleotide change
EP2577300A4 (en) MULTIFUNCTIONAL PARTICLE SCANNING
SG11201400635UA (en) Method for detecting target nucleic acid
EP2771208A4 (en) SYSTEM FOR DISPLAYING HAZARD
EP2714971A4 (en) METHOD FOR DETERMINING, IDENTIFYING AND INSULATING CELL-PENETRATING PEPTIDES
EP2726628A4 (en) METHOD FOR DETECTING GENEUS GENES
ITRM20120383A1 (it) Metodo e kit per la rivelazione di anticorpi.
GB201120965D0 (en) System and method for detection of analytes
ZA201301307B (en) Method for testing reheating crack sensitivity of dissimilar steel
BR112014007556A2 (pt) método de determinação de sinais estacionários para o diagnóstico de um sistema eletromecânico
CL2014001406A1 (es) Un metodo de deteccion homogeneo para un proceso de pcr usando fret que detecta la presencia o ausencia de un snp de haahasll-a122(at)t dentro del gen haahasll.
EP3054283A4 (en) Method for detecting target substance
EP2757377A4 (en) METHOD FOR DETECTION OF PANCREATIC DISEASE MARKER