IN2014CN04920A - - Google Patents

Download PDF

Info

Publication number
IN2014CN04920A
IN2014CN04920A IN4920CHN2014A IN2014CN04920A IN 2014CN04920 A IN2014CN04920 A IN 2014CN04920A IN 4920CHN2014 A IN4920CHN2014 A IN 4920CHN2014A IN 2014CN04920 A IN2014CN04920 A IN 2014CN04920A
Authority
IN
India
Prior art keywords
cells
adult
producing
reprogrammed
differentiated
Prior art date
Application number
Other languages
English (en)
Inventor
Scott Noggle
Kevin Eggan
Stephen Chang
Susan L Solomon
Original Assignee
New York Stem Cell Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Stem Cell Foundation filed Critical New York Stem Cell Foundation
Publication of IN2014CN04920A publication Critical patent/IN2014CN04920A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/04Flat or tray type, drawers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1307Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
IN4920CHN2014 2011-12-01 2012-11-30 IN2014CN04920A (he)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161565818P 2011-12-01 2011-12-01
US201161580007P 2011-12-23 2011-12-23
US201261700792P 2012-09-13 2012-09-13
PCT/US2012/067417 WO2013082509A1 (en) 2011-12-01 2012-11-30 Automated system for producing induced pluripotent stem cells or differentiated cells

Publications (1)

Publication Number Publication Date
IN2014CN04920A true IN2014CN04920A (he) 2015-09-18

Family

ID=48536128

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4920CHN2014 IN2014CN04920A (he) 2011-12-01 2012-11-30

Country Status (14)

Country Link
US (3) US10273459B2 (he)
EP (2) EP3653698A1 (he)
JP (1) JP6257520B2 (he)
KR (5) KR102039202B1 (he)
CN (2) CN104080906A (he)
AU (3) AU2012345676B2 (he)
BR (2) BR122020005735B1 (he)
CA (2) CA3118842C (he)
DK (1) DK2785829T3 (he)
ES (1) ES2773863T3 (he)
IL (3) IL299477A (he)
IN (1) IN2014CN04920A (he)
WO (1) WO2013082509A1 (he)
ZA (2) ZA201403945B (he)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102039202B1 (ko) 2011-12-01 2019-10-31 뉴욕 스템 셀 파운데이션, 인코포레이티드 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템
US10428309B2 (en) 2011-12-01 2019-10-01 New York Stem Cell Foundation, Inc. Systems and methods for producing stem cells and differentiated cells
US20160130561A1 (en) * 2013-06-13 2016-05-12 The New York Stem Cell Foundation Inc. Pluripotent stem cells derived from non-cryoprotected frozen tissue and methods for making and using the same
EP3013941B1 (en) * 2013-06-27 2018-10-31 New York Stem Cell Foundation, Inc. Improved systems and methods for producing stem cells and differentiated cells
WO2015023658A2 (en) * 2013-08-12 2015-02-19 Invivosciences Inc. Automated cell culture system and method
WO2016105578A1 (en) * 2014-12-26 2016-06-30 The New York Stem Cell Foundation Improved systems and methods for producing stem cells, differentiated cells, and genetically edited cells
WO2016118824A1 (en) 2015-01-22 2016-07-28 Regenerative Medical Solutions, Inc. Markers for differentiation of stem cells into differentiated cell populations
CN114717183A (zh) 2015-08-31 2022-07-08 爱平世股份有限公司 多能干细胞制造系统和生产诱导多能干细胞的方法
CN105567642B (zh) * 2016-02-01 2019-07-12 中国科学院生物物理研究所 一种着色性干皮病人多能干细胞的制备方法
US11149250B2 (en) 2016-03-03 2021-10-19 New York Stem Cell Foundation, Inc. Microglia derived from pluripotent stem cells and methods of making and using the same
JP2019521715A (ja) * 2016-07-21 2019-08-08 セリアドCelyad 細胞を自動的に独立並列してバッチ処理するための方法および装置
US11259520B2 (en) * 2016-08-04 2022-03-01 Fanuc Corporation Stem cell manufacturing system, stem cell information management system, cell transport apparatus, and stem cell frozen storage apparatus
US10373109B2 (en) 2016-08-04 2019-08-06 Fanuc Corporation System and method for iPS cell bank using media
US10354218B2 (en) 2016-08-04 2019-07-16 Fanuc Corporation System and method for iPS cell bank using internet technology
JP2020500023A (ja) * 2016-11-18 2020-01-09 ニュー ヨーク ステム セル ファウンデーション,インコーポレイテッド マイクロ流体システムおよびその使用の方法
EP4039792A1 (en) * 2017-01-20 2022-08-10 FUJIFILM Corporation Cell culture apparatus and cell culture method
EP3587556A4 (en) * 2017-02-24 2021-04-14 Koji Tanabe CELL TREATMENT DEVICE, SUSPENSION CULTURE VESSEL AND STEM CELL INDUCTION METHOD
JP6530876B2 (ja) * 2017-02-27 2019-06-12 剛士 田邊 細胞処理システム及び細胞処理装置
US20190382706A1 (en) * 2017-02-27 2019-12-19 Koji Tanabe Somatic cell production system
EP3848459A1 (en) * 2017-06-30 2021-07-14 Inscripta, Inc. Automated cell processing methods, modules, instruments and systems
GB2564437B (en) * 2017-07-10 2020-11-04 Univ Brunel Method of testing a gene therapy vector using induced pluripotent stem cells
AU2018324180A1 (en) 2017-09-01 2020-03-19 Lonza Cologne Gmbh End-to-end cell therapy automation
CN111372650A (zh) * 2017-09-30 2020-07-03 因思科瑞普特公司 流通式电穿孔仪器
EP3808834A4 (en) * 2018-06-13 2021-08-11 FUJIFILM Corporation INFORMATION PROCESSING DEVICE, DERIVATION METHOD AND DERIVATION PROGRAM
JP7090337B2 (ja) * 2019-03-20 2022-06-24 アイ ピース,インコーポレイテッド 細胞処理システム及び細胞処理装置
JP6530577B1 (ja) * 2019-03-20 2019-06-12 剛士 田邊 細胞処理システム及び細胞処理装置
JP6530874B1 (ja) * 2019-03-20 2019-06-12 剛士 田邊 細胞処理システム及び細胞処理装置
EP4038177A4 (en) * 2019-10-04 2024-01-24 New York Stem Cell Found Inc IMAGING SYSTEM AND METHOD OF USE THEREOF
US20230167412A1 (en) * 2019-11-28 2023-06-01 The University Of Hong Kong Mesenchymal stromal cells as a reprogramming source for ipsc induction
EP4355853A1 (en) * 2021-06-17 2024-04-24 Genentech, Inc. Automated cell culture system
WO2024020572A1 (en) 2022-07-22 2024-01-25 New York Stem Cell Foundation, Inc. Methods and compositions for the treatment of ptsd

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5994619A (en) 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
JP2001512689A (ja) 1997-08-11 2001-08-28 カイロン コーポレイション T細胞を遺伝子改変するための方法
US8026096B1 (en) 1998-10-08 2011-09-27 Protein Sciences Corporation In vivo active erythropoietin produced in insect cells
US20110171185A1 (en) * 1999-06-30 2011-07-14 Klimanskaya Irina V Genetically intact induced pluripotent cells or transdifferentiated cells and methods for the production thereof
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6959438B2 (en) 2000-12-06 2005-10-25 Microsoft Corporation Interface and related methods for dynamically generating a filter graph in a development system
AU2003218572B2 (en) * 2002-04-08 2009-08-20 Octane Biotech, Inc. Automated tissue engineering system
EP1445320A1 (en) 2003-02-05 2004-08-11 ARTEMIS Pharmaceuticals GmbH Automated gene-targeting using non-toxic detectable markers
JP2007529515A (ja) * 2004-03-19 2007-10-25 サイトリ セラピューティクス インコーポレイテッド 再生細胞を収容する細胞担体及び細胞担体封じ込め装置
US20070238175A1 (en) 2006-04-06 2007-10-11 Chi Alfred L Standardization of processes for culturing primary cells
GB0704406D0 (en) 2007-03-07 2007-04-18 Stem Cell Sciences Uk Ltd Automated culture of stem cells
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
DK3293256T3 (da) 2007-06-29 2019-08-12 Fujifilm Cellular Dynamics Inc Automatiseret fremgangsmåde og apparatur til dyrkning af embryonale stamceller
WO2009023246A2 (en) * 2007-08-14 2009-02-19 Wake Forest University Health Sciences Pluripotent adult stem cells
US10047346B2 (en) 2008-08-08 2018-08-14 Mayo Foundation For Medical Education And Research Method of treating heart tissue using induced pluripotent stem cells
US9045737B2 (en) * 2008-12-13 2015-06-02 Dnamicroarray, Inc. Artificial three-dimensional microenvironment niche culture
CA2747398C (en) * 2008-12-17 2023-06-20 The Scripps Research Institute Generation and maintenance of stem cells
EP2398897B1 (en) * 2009-02-20 2017-06-28 Cellular Dynamics International, Inc. Methods and compositions for the differentiation of stem cells
KR101720961B1 (ko) 2009-02-27 2017-03-29 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 다능성 세포의 분화
CN101580816B (zh) 2009-04-23 2012-02-29 中国科学院广州生物医药与健康研究院 诱导多能性干细胞快速高效产生的新型无血清培养基以及使用其的方法
US20110020814A1 (en) * 2009-06-05 2011-01-27 Ipierian, Inc. Methods and compositions for selection of stem cells
CN102459575A (zh) * 2009-06-05 2012-05-16 细胞动力国际有限公司 重编程t细胞和造血细胞的方法
US20120252697A1 (en) 2009-09-01 2012-10-04 Mcmaster University Transformed human pluripotent stem cells and associated methods
WO2011037301A1 (ko) * 2009-09-22 2011-03-31 서울대학교병원 성체세포로부터 만능줄기세포를 유도하는 방법 및 그 방법에 의해 제조된 만능줄기세포
WO2011130624A2 (en) 2010-04-16 2011-10-20 Immune Disease Institute, Inc. Sustained polypeptide expression from synthetic, modified rnas and uses thereof
US20110306516A1 (en) 2010-06-15 2011-12-15 The New York Stem Cell Foundation Methods for producing induced pluripotent stem cells
KR20140063501A (ko) 2010-12-22 2014-05-27 페이트 세러퓨틱스, 인코포레이티드 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼
EP2481795A1 (en) 2011-01-28 2012-08-01 Universität für Bodenkultur Wien Method of generating induced pluripotent stem cells and differentiated cells
KR102039202B1 (ko) * 2011-12-01 2019-10-31 뉴욕 스템 셀 파운데이션, 인코포레이티드 유도 다능성 줄기 세포 또는 분화된 세포를 제조하기 위한 자동화 시스템

Also Published As

Publication number Publication date
KR102039202B1 (ko) 2019-10-31
CN104080906A (zh) 2014-10-01
IL232869B (he) 2022-02-01
KR20190124326A (ko) 2019-11-04
KR102439238B1 (ko) 2022-08-31
WO2013082509A1 (en) 2013-06-06
IL289822B2 (he) 2023-06-01
BR112014013152B1 (pt) 2021-08-31
AU2021212081B2 (en) 2024-02-29
US20210332330A1 (en) 2021-10-28
IL299477A (he) 2023-02-01
JP6257520B2 (ja) 2018-01-10
CN110724636A (zh) 2020-01-24
BR112014013152A2 (pt) 2017-06-13
IL232869A0 (he) 2014-07-31
DK2785829T3 (da) 2020-01-27
KR102631374B1 (ko) 2024-01-29
EP2785829A1 (en) 2014-10-08
US10273459B2 (en) 2019-04-30
CA2857295A1 (en) 2013-06-06
US11732242B2 (en) 2023-08-22
BR122020005735B1 (pt) 2021-12-28
AU2012345676B2 (en) 2018-10-04
CA3118842C (en) 2023-12-12
ZA201403945B (en) 2018-08-29
ZA201803502B (en) 2022-12-21
AU2018286561A1 (en) 2019-01-24
KR20220141823A (ko) 2022-10-20
IL289822A (he) 2022-03-01
CA3118842A1 (en) 2013-06-06
AU2012345676A1 (en) 2014-06-19
US20130345094A1 (en) 2013-12-26
AU2021212081A1 (en) 2021-08-26
KR20140101393A (ko) 2014-08-19
KR20210096700A (ko) 2021-08-05
EP2785829A4 (en) 2015-04-29
EP3653698A1 (en) 2020-05-20
ES2773863T3 (es) 2020-07-15
EP2785829B1 (en) 2019-10-16
KR20240019378A (ko) 2024-02-14
US20190352613A1 (en) 2019-11-21
CA2857295C (en) 2021-06-29
US10968435B2 (en) 2021-04-06
JP2015502747A (ja) 2015-01-29

Similar Documents

Publication Publication Date Title
IN2014CN04920A (he)
MX2019007742A (es) Metodos para aislar microvesiculas.
TW201612312A (en) Meristematic plant cells and method of isolating them
IN2014DN09302A (he)
EP2966163A4 (en) CULTURE SYSTEM FOR PLURIPOTENT STEM CELLS AND METHOD FOR SUB-CULTURE OF PLURIPOTENT STEM CELLS
EP3453753A4 (en) METHOD OF SUB-CULTURE OF PLURIPOTENT STEM CELLS
EP3064575A4 (en) Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into hepatocyte
EP3064574A4 (en) Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into chondrocyte
EP3064573A4 (en) Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into neuron
EP3202896A4 (en) Method for culturing pluripotent stem cells
IL249170A0 (he) שיטה ליצירת תאי גזע פלוריפוטנטים מושרים מתאי גזע מזנכימליים בשימוש פרקציית phlorotannin
IL281751A (he) שיטות לגרימת התמיינות בתאי גזע מזנכימאלים
EP3070159A4 (en) METHOD AND PLANT FOR CURING PLURIPOTENT STEM CELLS
IN2014DN10614A (he)
EP3202911A4 (en) Method for determining undifferentiated state of pluripotent stem cells by culture medium analysis
MX2016014008A (es) Metodo para diferenciacion de celulas madre pluripotentes en cardiomiocitos.
EP2984101A4 (en) Kits and methods for isolating protein from biological and environmental samples
PH12015502113A1 (en) Early detection and elimination of non germ-line events in the soybean transformation process
EP3156481A4 (en) Method for manufacturing induced pluripotent stem cells from adipose-derived mesenchymal stem cells and induced pluripotent stem cells manufactured by same method
WO2015175534A3 (en) Compositions and methods employing stem cell-derived cardiomyocytes
EP3064571A4 (en) Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into osteoblast
EP3064570A4 (en) Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into adipocyte
EP3824912A4 (en) PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE
EP3770249A4 (en) METHOD OF THREE-DIMENSIONAL CULTIVATION OF PLURIPOTENT STEM CELLS
EP3508569A4 (en) METHOD FOR OBTAINING MICROGLY FROM PLURIPOTENT STEM CELLS