IN2014CN02584A - - Google Patents

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Publication number
IN2014CN02584A
IN2014CN02584A IN2584CHN2014A IN2014CN02584A IN 2014CN02584 A IN2014CN02584 A IN 2014CN02584A IN 2584CHN2014 A IN2584CHN2014 A IN 2584CHN2014A IN 2014CN02584 A IN2014CN02584 A IN 2014CN02584A
Authority
IN
India
Prior art keywords
bdo
produce
naturally occurring
organisms
non naturally
Prior art date
Application number
Other languages
English (en)
Inventor
Anthony P Burgard
Mark J Burk
Robin E Osterhout
Priti Pharkya
Jingyi Li
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of IN2014CN02584A publication Critical patent/IN2014CN02584A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/16Dicarboxylic acids and dihydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/32Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN2584CHN2014 2011-09-08 2012-09-07 IN2014CN02584A (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161532492P 2011-09-08 2011-09-08
US201161541951P 2011-09-30 2011-09-30
US201161558959P 2011-11-11 2011-11-11
US201261649039P 2012-05-18 2012-05-18
US201261655355P 2012-06-04 2012-06-04
PCT/US2012/054152 WO2013036764A1 (en) 2011-09-08 2012-09-07 Eukaryotic organisms and methods for producing 1,3-butanediol

Publications (1)

Publication Number Publication Date
IN2014CN02584A true IN2014CN02584A (pl) 2015-08-07

Family

ID=47830417

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2584CHN2014 IN2014CN02584A (pl) 2011-09-08 2012-09-07

Country Status (10)

Country Link
US (2) US20130066035A1 (pl)
EP (1) EP2753699A4 (pl)
KR (1) KR20140058691A (pl)
CN (1) CN103917651A (pl)
BR (1) BR112014005352A2 (pl)
CA (1) CA2848064A1 (pl)
IN (1) IN2014CN02584A (pl)
MX (1) MX2014002787A (pl)
SG (1) SG11201400466TA (pl)
WO (1) WO2013036764A1 (pl)

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US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
CN104870645A (zh) * 2012-09-24 2015-08-26 昭和电工株式会社 丁二醇的制造方法
US20160040172A1 (en) 2013-03-15 2016-02-11 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
WO2014152665A1 (en) 2013-03-15 2014-09-25 Genomatica, Inc. Process and systems for obtaining 1,4-butanediol from fermentation broths
EP3008178A1 (en) 2013-06-14 2016-04-20 Technical University of Denmark Microbial production of 3-hydroxypropionic acid
WO2015057154A2 (en) 2013-10-18 2015-04-23 Biopetrolia Ab ENGINEERING OF ACETYL-CoA METABOLISM IN YEAST
WO2015077752A1 (en) * 2013-11-25 2015-05-28 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
SI3077501T1 (sl) 2013-12-03 2022-02-28 Genomatica, Inc. Mikroorganizmi in metode za izboljšanje donosa izdelkov z uporabo sinteze acetil-coa
EP3744830B1 (en) 2013-12-27 2023-11-22 Genomatica, Inc. Methods and organisms with increased carbon flux efficiencies
US20170298363A1 (en) 2014-09-18 2017-10-19 Genomatica, Inc Non-natural microbial organisms with improved energetic efficiency
US10173947B2 (en) 2014-12-12 2019-01-08 Versalis S.P.A. Process for the production of 1,3-butadiene from 1,3-butanediol
EP3262019A1 (en) 2015-02-23 2018-01-03 Versalis S.p.A. Process for the dehydration of oxygenated compounds
CN108026214B (zh) 2015-05-30 2021-03-02 基因组股份公司 乙烯基异构酶-脱水酶、烯醇脱水酶、芳樟醇脱水酶和/或巴豆醇脱水酶及其制备和使用
CN104988168A (zh) * 2015-06-08 2015-10-21 天津大学 乙酰辅酶a增强模块在增强7-脱氢胆甾醇在微生物中合成的应用
CN104988162B (zh) * 2015-06-08 2020-03-17 天津大学 辅因子再生模块在增强次级代谢产物在微生物中合成的应用
KR101704212B1 (ko) 2015-06-12 2017-02-08 씨제이제일제당 (주) 젖산을 생산하는 미생물 및 이를 이용한 젖산 제조 방법
WO2017006183A1 (en) * 2015-07-08 2017-01-12 Conradie Alex Van Eck Methods and host cells for enhancing production of 1,3-butanediol
EP3325608B1 (en) * 2015-07-21 2021-11-24 The Governing Council of the University of Toronto Methods and microorganisms for the production of 1,3-butanediol
PL3359655T3 (pl) * 2015-10-06 2020-05-18 Dsm Ip Assets B.V. Komórka eukariotyczna ze zwiększonym wytwarzaniem produktu fermentacji
CN115322261A (zh) 2015-10-30 2022-11-11 基因组股份公司 甲醇脱氢酶融合蛋白
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2018183640A1 (en) 2017-03-31 2018-10-04 Genomatica, Inc. 3-hydroxybutyryl-coa dehydrogenase variants and methods of use
BR112019020461A2 (pt) 2017-03-31 2020-06-09 Genomatica Inc variantes de aldeído desidrogenase e métodos de uso
US11608488B2 (en) 2017-07-11 2023-03-21 Adisseo France S.A.S. Enhanced metabolite-producing yeast
CA3069697A1 (en) * 2017-07-13 2019-01-17 Radici Chimica S.P.A. Biological methods for modifying cellular carbon flux
MY201926A (en) 2017-07-13 2024-03-24 Radici Chimica S P A Biological methods for preparing terpenes
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
WO2020006058A2 (en) 2018-06-26 2020-01-02 Genomatica, Inc. Engineered microorganisms with g3p---> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy
AU2019344574B2 (en) 2018-09-21 2024-01-25 Versalis S.P.A. Process for bio-1,3-butanediol purification from a fermentation broth
US11634692B2 (en) 2018-09-26 2023-04-25 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
US20210332377A1 (en) * 2018-10-12 2021-10-28 Yield10 Bioscience, Inc. Genetically engineered plants that express a quinone-utilizing malate dehydrogenase
CN111386345B (zh) * 2018-10-30 2023-05-16 绿色地球研究所株式会社 1,3-丙二醇的制造方法
CN110564662B (zh) * 2019-09-30 2022-03-25 南京农业大学 一种整合型高效表达乙醛脱氢酶枯草杆菌的构建方法
CN117701489B (zh) * 2024-02-05 2024-05-10 北京绿色康成生物技术有限公司 一种提高大肠杆菌生产1,3-丁二醇的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA963971B (en) * 1995-05-18 1996-11-25 Univ Stellenbosch A method and nucleotide sequence for transforming microorganisms
EP2078092A2 (en) * 2006-09-28 2009-07-15 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
BRPI0909989A2 (pt) * 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
AU2010298004B2 (en) * 2009-09-27 2016-02-25 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
JP2013513384A (ja) * 2009-12-10 2013-04-22 ジェノマティカ・インコーポレイテッド 合成ガスまたは他のガス状の炭素源およびメタノールを1,3−ブタンジオールへ変換するための方法および生物
US8871488B2 (en) * 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases

Also Published As

Publication number Publication date
EP2753699A1 (en) 2014-07-16
WO2013036764A1 (en) 2013-03-14
EP2753699A4 (en) 2015-08-19
US20130066035A1 (en) 2013-03-14
CN103917651A (zh) 2014-07-09
SG11201400466TA (en) 2014-04-28
US20170247709A1 (en) 2017-08-31
AU2012304428A1 (en) 2013-05-02
KR20140058691A (ko) 2014-05-14
MX2014002787A (es) 2014-12-08
CA2848064A1 (en) 2013-03-14
AU2012304428B2 (en) 2016-03-17
BR112014005352A2 (pt) 2017-03-28

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