IN2014CN02584A - - Google Patents

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Publication number
IN2014CN02584A
IN2014CN02584A IN2584CHN2014A IN2014CN02584A IN 2014CN02584 A IN2014CN02584 A IN 2014CN02584A IN 2584CHN2014 A IN2584CHN2014 A IN 2584CHN2014A IN 2014CN02584 A IN2014CN02584 A IN 2014CN02584A
Authority
IN
India
Prior art keywords
bdo
produce
naturally occurring
organisms
non naturally
Prior art date
Application number
Other languages
English (en)
Inventor
Anthony P Burgard
Mark J Burk
Robin E Osterhout
Priti Pharkya
Jingyi Li
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of IN2014CN02584A publication Critical patent/IN2014CN02584A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/16—Dicarboxylic acids and dihydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN2584CHN2014 2011-09-08 2012-09-07 IN2014CN02584A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161532492P 2011-09-08 2011-09-08
US201161541951P 2011-09-30 2011-09-30
US201161558959P 2011-11-11 2011-11-11
US201261649039P 2012-05-18 2012-05-18
US201261655355P 2012-06-04 2012-06-04
PCT/US2012/054152 WO2013036764A1 (en) 2011-09-08 2012-09-07 Eukaryotic organisms and methods for producing 1,3-butanediol

Publications (1)

Publication Number Publication Date
IN2014CN02584A true IN2014CN02584A (ja) 2015-08-07

Family

ID=47830417

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2584CHN2014 IN2014CN02584A (ja) 2011-09-08 2012-09-07

Country Status (10)

Country Link
US (2) US20130066035A1 (ja)
EP (1) EP2753699A4 (ja)
KR (1) KR20140058691A (ja)
CN (1) CN103917651A (ja)
BR (1) BR112014005352A2 (ja)
CA (1) CA2848064A1 (ja)
IN (1) IN2014CN02584A (ja)
MX (1) MX2014002787A (ja)
SG (1) SG11201400466TA (ja)
WO (1) WO2013036764A1 (ja)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
US20150252390A1 (en) * 2012-09-24 2015-09-10 Showa Denko Manufacturing method for a butanediol
US20160040172A1 (en) 2013-03-15 2016-02-11 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
CN105209414B (zh) 2013-03-15 2018-04-17 基因组股份公司 用于从发酵肉汤中获得1,4‑丁二醇的方法和系统
US10066245B2 (en) 2013-06-14 2018-09-04 Technical University Of Denmark Microbial production of 3-hydroxypropionic acid
US10704050B2 (en) 2013-10-18 2020-07-07 Biopetrolia Ab Engineering of acetyl-CoA metabolism in yeast
EP3074504A4 (en) * 2013-11-25 2017-05-03 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
SI3077501T1 (sl) 2013-12-03 2022-02-28 Genomatica, Inc. Mikroorganizmi in metode za izboljšanje donosa izdelkov z uporabo sinteze acetil-coa
EP3087174B1 (en) 2013-12-27 2020-05-13 Genomatica, Inc. Methods and organisms with increased carbon flux efficiencies
EP3194604B1 (en) 2014-09-18 2020-02-26 Genomatica, Inc. Non-natural microbial organisms with improved energetic efficiency
US10173947B2 (en) 2014-12-12 2019-01-08 Versalis S.P.A. Process for the production of 1,3-butadiene from 1,3-butanediol
EP3262019B1 (en) 2015-02-23 2024-07-31 Versalis S.p.A. Process for the dehydration of oxygenated compounds
CN108026214B (zh) 2015-05-30 2021-03-02 基因组股份公司 乙烯基异构酶-脱水酶、烯醇脱水酶、芳樟醇脱水酶和/或巴豆醇脱水酶及其制备和使用
CN104988162B (zh) * 2015-06-08 2020-03-17 天津大学 辅因子再生模块在增强次级代谢产物在微生物中合成的应用
CN104988168A (zh) * 2015-06-08 2015-10-21 天津大学 乙酰辅酶a增强模块在增强7-脱氢胆甾醇在微生物中合成的应用
KR101704212B1 (ko) 2015-06-12 2017-02-08 씨제이제일제당 (주) 젖산을 생산하는 미생물 및 이를 이용한 젖산 제조 방법
US20170009263A1 (en) * 2015-07-08 2017-01-12 Invista North America S.A.R.L. Methods and host cells for enhancing production of 1, 3-butanediol
US10626423B2 (en) * 2015-07-21 2020-04-21 The Governing Council Of The University Of Toronto Methods and microorganisms for the production of 1,3-butanediol
WO2017060195A1 (en) * 2015-10-06 2017-04-13 Dsm Ip Assets B.V. Eukaryotic cell with increased production of fermentation product
SG11201803164SA (en) 2015-10-30 2018-05-30 Genomatica Inc Methanol dehydrogenase fusion proteins
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11898172B2 (en) 2017-03-31 2024-02-13 Genomatica, Inc. 3-hydroxybutyryl-CoA dehydrogenase variants and methods of use
WO2018183664A1 (en) 2017-03-31 2018-10-04 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of use
US11608488B2 (en) 2017-07-11 2023-03-21 Adisseo France S.A.S. Enhanced metabolite-producing yeast
WO2019014309A1 (en) * 2017-07-13 2019-01-17 Verdezyne (Abc), Llc BIOLOGICAL METHODS FOR MODIFYING A CELL CARBON FLOW
US11781148B2 (en) 2017-07-13 2023-10-10 Radici Chimica S.P.A. Biological methods for preparing terpenes
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
JP2021528977A (ja) 2018-06-26 2021-10-28 ジェノマティカ， インコーポレイテッド グリセルアルデヒド３−リン酸（ｇ３ｐ）を３−ホスホグリセリン酸（３ｐｇ）に変換する酵素および／またはフルクトース−１，６−ビスホスファターゼを有する組換え微生物（合成または増強されたメチロトロフィーを有するものを含む）
US20210380512A1 (en) 2018-09-21 2021-12-09 Eni S.P.A. Process for bio-1,3-butanediol purification from a fermentation broth
US11634692B2 (en) 2018-09-26 2023-04-25 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
WO2020077059A1 (en) * 2018-10-12 2020-04-16 Yield10 Bioscience, Inc. Genetically engineered plants that express a quinone-utilizing malate dehydrogenase
WO2020090017A1 (ja) * 2018-10-30 2020-05-07 Ｇｒｅｅｎ Ｅａｒｔｈ Ｉｎｓｔｉｔｕｔｅ 株式会社 １，３－プロパンジオールの製造方法
CN110564662B (zh) * 2019-09-30 2022-03-25 南京农业大学 一种整合型高效表达乙醛脱氢酶枯草杆菌的构建方法
CN117701489B (zh) * 2024-02-05 2024-05-10 北京绿色康成生物技术有限公司 一种提高大肠杆菌生产1,3-丁二醇的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE449176T1 (de) * 1995-05-18 2009-12-15 Univ Stellenbosch Nukleinsäure für eine malat permease aus s.pombe kodierend und deren verwendungen
US8956850B2 (en) * 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
WO2008042338A2 (en) * 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
WO2011038364A1 (en) * 2009-09-27 2011-03-31 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
JP2013513384A (ja) * 2009-12-10 2013-04-22 ジェノマティカ・インコーポレイテッド 合成ガスまたは他のガス状の炭素源およびメタノールを１，３−ブタンジオールへ変換するための方法および生物
US8871488B2 (en) * 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases

Also Published As

Publication number Publication date
MX2014002787A (es) 2014-12-08
BR112014005352A2 (pt) 2017-03-28
WO2013036764A1 (en) 2013-03-14
CA2848064A1 (en) 2013-03-14
CN103917651A (zh) 2014-07-09
US20170247709A1 (en) 2017-08-31
EP2753699A1 (en) 2014-07-16
AU2012304428A1 (en) 2013-05-02
KR20140058691A (ko) 2014-05-14
AU2012304428B2 (en) 2016-03-17
EP2753699A4 (en) 2015-08-19
SG11201400466TA (en) 2014-04-28
US20130066035A1 (en) 2013-03-14

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