IN2013CH04757A - - Google Patents
Info
- Publication number
- IN2013CH04757A IN2013CH04757A IN4757CH2013A IN2013CH04757A IN 2013CH04757 A IN2013CH04757 A IN 2013CH04757A IN 4757CH2013 A IN4757CH2013 A IN 4757CH2013A IN 2013CH04757 A IN2013CH04757 A IN 2013CH04757A
- Authority
- IN
- India
- Prior art keywords
- methyl
- difluorophenyl
- triazol
- tetrahydrofuran
- formula
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 abstract 1
- -1 methyl-4-methyl benzene sulfonate compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN4757CH2013 IN2013CH04757A (enrdf_load_html_response) | 2013-10-22 | 2014-10-21 | |
| US15/031,536 US20160237066A1 (en) | 2013-10-22 | 2014-10-21 | Improved process for the preparation of ((3s,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl-4-methylbenzenesulfonate |
| PCT/IN2014/000673 WO2015059716A2 (en) | 2013-10-22 | 2014-10-21 | Improved process for the preparation of ((3s,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl-4-methylbenzenesulfonate |
| EP14855720.0A EP3060559A4 (en) | 2013-10-22 | 2014-10-21 | Improved process for the preparation of ((3s,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl-4-methylbenzenesulfonate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN4757CH2013 IN2013CH04757A (enrdf_load_html_response) | 2013-10-22 | 2014-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013CH04757A true IN2013CH04757A (enrdf_load_html_response) | 2015-04-24 |
Family
ID=52993715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4757CH2013 IN2013CH04757A (enrdf_load_html_response) | 2013-10-22 | 2014-10-21 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160237066A1 (enrdf_load_html_response) |
| EP (1) | EP3060559A4 (enrdf_load_html_response) |
| IN (1) | IN2013CH04757A (enrdf_load_html_response) |
| WO (1) | WO2015059716A2 (enrdf_load_html_response) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106317032A (zh) * | 2015-06-15 | 2017-01-11 | 重庆圣华曦药业股份有限公司 | 一种制备高纯度的泊沙康唑的方法 |
| US10457668B2 (en) | 2015-09-23 | 2019-10-29 | Biocon Limited | Crystalline forms of posaconazole intermediate and process for the preparation of amorphous posaconazole |
| CN105440022B (zh) * | 2015-12-31 | 2017-11-03 | 重庆威鹏药业有限公司 | 泊沙康唑主环的制备方法 |
| CN105606736A (zh) * | 2016-01-27 | 2016-05-25 | 重庆华邦制药有限公司 | 分离测定泊沙康唑中间体z1及其有关物质的方法 |
| DK3424911T3 (da) * | 2016-03-04 | 2021-10-11 | Zhejiang Ausun Pharmaceutical Co Ltd | Posaconazol, sammensætning, intermediat, fremstillingsfremgangsmåde derfor og anvendelser deraf |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| CN106397417A (zh) * | 2016-08-30 | 2017-02-15 | 甘肃皓天化学科技有限公司 | 用于制备泊沙康唑的中间体的制备方法 |
| WO2019077627A1 (en) * | 2017-10-16 | 2019-04-25 | Metrochem Api Pvt Ltd. | PROCESS FOR PRODUCING POSACONAZOLE |
| US20220001295A1 (en) * | 2018-11-19 | 2022-01-06 | PREM ANAND MUKUND Honavar | An improved process to increase the performance on filtrate extention |
| CN109187824A (zh) * | 2018-11-30 | 2019-01-11 | 无锡福祈制药有限公司 | 一种泊沙康唑的高效液相色谱分析方法 |
| CN112898279A (zh) * | 2019-11-19 | 2021-06-04 | 爱之源生物科技有限公司 | 一种高纯度的泊沙康唑的精制方法 |
| CN111675702A (zh) * | 2020-04-23 | 2020-09-18 | 陕西博森生物制药股份集团有限公司 | 一种泊沙康唑的制备方法 |
| CN113666915B (zh) * | 2021-08-27 | 2022-08-16 | 江苏海洋大学 | 一种泊沙康唑中间体的制备方法 |
| CN117510380B (zh) * | 2024-01-08 | 2024-04-05 | 寿光诺盟化工有限公司 | 一种苯磺酸酯的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5403937A (en) * | 1993-04-30 | 1995-04-04 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
| WO2009141837A2 (en) * | 2008-05-21 | 2009-11-26 | Ind-Swift Laboratories Limited | Process for preparing posaconazole and intermediates thereof |
| RU2585760C2 (ru) * | 2010-05-19 | 2016-06-10 | Сандоз Аг | Способ получения хиральных триазолонов |
| CN108329303A (zh) * | 2011-06-16 | 2018-07-27 | 桑多斯股份公司 | 制备手性化合物的方法 |
| US9102664B2 (en) * | 2011-09-19 | 2015-08-11 | Msn Laboratories Private Limited | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof |
-
2014
- 2014-10-21 WO PCT/IN2014/000673 patent/WO2015059716A2/en active Application Filing
- 2014-10-21 US US15/031,536 patent/US20160237066A1/en not_active Abandoned
- 2014-10-21 EP EP14855720.0A patent/EP3060559A4/en not_active Withdrawn
- 2014-10-21 IN IN4757CH2013 patent/IN2013CH04757A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015059716A3 (en) | 2015-07-02 |
| EP3060559A4 (en) | 2017-05-24 |
| US20160237066A1 (en) | 2016-08-18 |
| EP3060559A2 (en) | 2016-08-31 |
| WO2015059716A2 (en) | 2015-04-30 |
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