IN2012DN03428A - - Google Patents

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Publication number
IN2012DN03428A
IN2012DN03428A IN3428DEN2012A IN2012DN03428A IN 2012DN03428 A IN2012DN03428 A IN 2012DN03428A IN 3428DEN2012 A IN3428DEN2012 A IN 3428DEN2012A IN 2012DN03428 A IN2012DN03428 A IN 2012DN03428A
Authority
IN
India
Prior art keywords
pharmaceutical compositions
nitrites
compositions
prodrugs
formulated
Prior art date
Application number
Other languages
English (en)
Inventor
Christopher Kevil
Anthony Giordano
Douglas R Flanagan
Panayiotis P Constantinides
Original Assignee
Theravasc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravasc Inc filed Critical Theravasc Inc
Publication of IN2012DN03428A publication Critical patent/IN2012DN03428A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IN3428DEN2012 2009-10-14 2010-10-14 IN2012DN03428A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25148309P 2009-10-14 2009-10-14
PCT/US2010/052683 WO2011047161A1 (en) 2009-10-14 2010-10-14 Pharmaceutical formulations of nitrite and uses thereof

Publications (1)

Publication Number Publication Date
IN2012DN03428A true IN2012DN03428A (enExample) 2015-10-23

Family

ID=43855036

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3428DEN2012 IN2012DN03428A (enExample) 2009-10-14 2010-10-14

Country Status (10)

Country Link
US (4) US10463689B2 (enExample)
EP (1) EP2488035B1 (enExample)
JP (3) JP5758904B2 (enExample)
CN (2) CN107260756A (enExample)
AU (1) AU2010306755B2 (enExample)
CA (1) CA2777066C (enExample)
ES (1) ES2633618T3 (enExample)
IL (1) IL219155A0 (enExample)
IN (1) IN2012DN03428A (enExample)
WO (1) WO2011047161A1 (enExample)

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* Cited by examiner, † Cited by third party
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US9649334B2 (en) 2007-11-15 2017-05-16 The Uab Research Foundation Use of nitrite salts in chronic ischemia
US20120237617A1 (en) 2009-06-18 2012-09-20 Theravasc Inc. Use of nitrite salts in treating tissue damage
WO2011047161A1 (en) * 2009-10-14 2011-04-21 TheraVasc, LLC Pharmaceutical formulations of nitrite and uses thereof
BR112014003414B1 (pt) 2011-08-17 2021-09-21 Board Of Regents, The University Of Texas System Composição e sistema de entrega oral para aumento de níveis fisiológicos e terapêuticos de óxido nítrico
US8627204B2 (en) * 2011-10-18 2014-01-07 Microsoft Corporation Custom optimization of web pages
JP2016509030A (ja) 2013-02-20 2016-03-24 セラバスク インコーポレーテッド ニトライトの医薬製剤及びそれらの使用
EP2994165A4 (en) * 2013-05-10 2017-01-04 Nitromega Corp. Nutritional or dietary supplements containing fatty acids and nitrite
GB201309092D0 (en) * 2013-05-20 2013-07-03 Edixomed Ltd Transdermal delivery system
US20170349438A1 (en) 2016-06-06 2017-12-07 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
JP2020508308A (ja) * 2017-02-20 2020-03-19 ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュアル アンド メカニカル カレッジ 心房細動の治療及び予防における硫化水素及び/又は亜硝酸塩
US11850271B1 (en) * 2023-05-16 2023-12-26 King Faisal University Topical skin cream

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US4650484A (en) 1983-02-03 1987-03-17 Alza Corporation Method for treating ischemic conditions
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US6709681B2 (en) 1995-02-17 2004-03-23 Aberdeen University Acidified nitrite as an antimicrobial agent
US20110196039A9 (en) * 1994-10-05 2011-08-11 Kaesemeyer Wayne H Controlled release arginine formulations
US5648101A (en) 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
US5770645A (en) 1996-08-02 1998-06-23 Duke University Medical Center Polymers for delivering nitric oxide in vivo
US5994444A (en) * 1997-10-16 1999-11-30 Medtronic, Inc. Polymeric material that releases nitric oxide
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Also Published As

Publication number Publication date
US20200085861A1 (en) 2020-03-19
JP6125567B2 (ja) 2017-05-10
US20200297756A1 (en) 2020-09-24
US20160067279A1 (en) 2016-03-10
EP2488035A1 (en) 2012-08-22
ES2633618T3 (es) 2017-09-22
JP2013508289A (ja) 2013-03-07
JP2017141275A (ja) 2017-08-17
EP2488035B1 (en) 2017-04-26
US20110086069A1 (en) 2011-04-14
CN102686111A (zh) 2012-09-19
AU2010306755B2 (en) 2015-12-24
WO2011047161A1 (en) 2011-04-21
CA2777066C (en) 2020-02-18
IL219155A0 (en) 2012-06-28
US10307441B2 (en) 2019-06-04
CA2777066A1 (en) 2011-04-21
CN107260756A (zh) 2017-10-20
JP2015180674A (ja) 2015-10-15
JP5758904B2 (ja) 2015-08-05
US10463689B2 (en) 2019-11-05
AU2010306755A1 (en) 2012-05-03
EP2488035A4 (en) 2013-07-31

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