IL219155A0 - Pharmaceutical formulations of nitrite and uses thereof - Google Patents
Pharmaceutical formulations of nitrite and uses thereofInfo
- Publication number
- IL219155A0 IL219155A0 IL219155A IL21915512A IL219155A0 IL 219155 A0 IL219155 A0 IL 219155A0 IL 219155 A IL219155 A IL 219155A IL 21915512 A IL21915512 A IL 21915512A IL 219155 A0 IL219155 A0 IL 219155A0
- Authority
- IL
- Israel
- Prior art keywords
- nitrite
- pharmaceutical formulations
- formulations
- pharmaceutical
- Prior art date
Links
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25148309P | 2009-10-14 | 2009-10-14 | |
| PCT/US2010/052683 WO2011047161A1 (en) | 2009-10-14 | 2010-10-14 | Pharmaceutical formulations of nitrite and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL219155A0 true IL219155A0 (en) | 2012-06-28 |
Family
ID=43855036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL219155A IL219155A0 (en) | 2009-10-14 | 2012-04-15 | Pharmaceutical formulations of nitrite and uses thereof |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10463689B2 (enExample) |
| EP (1) | EP2488035B1 (enExample) |
| JP (3) | JP5758904B2 (enExample) |
| CN (2) | CN107260756A (enExample) |
| AU (1) | AU2010306755B2 (enExample) |
| CA (1) | CA2777066C (enExample) |
| ES (1) | ES2633618T3 (enExample) |
| IL (1) | IL219155A0 (enExample) |
| IN (1) | IN2012DN03428A (enExample) |
| WO (1) | WO2011047161A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101939014B (zh) | 2007-11-15 | 2016-04-27 | 路易斯安那州大学及农业和机械学院管理委员会 | 亚硝酸盐在慢性缺血中的应用 |
| WO2010147742A2 (en) | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| CA2777066C (en) * | 2009-10-14 | 2020-02-18 | TheraVasc, LLC | Pharmaceutical formulations of nitrite and uses thereof |
| WO2013026000A1 (en) | 2011-08-17 | 2013-02-21 | Board Of Regents, The University Of Texas System | Method of producing physiological and therapeutic levels of nitric oxide through an oral delivery system |
| US8627204B2 (en) * | 2011-10-18 | 2014-01-07 | Microsoft Corporation | Custom optimization of web pages |
| ES2741146T3 (es) | 2013-02-20 | 2020-02-10 | The Board Of Supervisors Of The Louisiana State Univ Mechanical And Agricultural College | Formulaciones farmacéuticas de nitrio y sus usos |
| US20160081962A1 (en) * | 2013-05-10 | 2016-03-24 | Nitromega Corp. | Nutritional or dietary supplements containing fatty acids and nitrite |
| GB201309092D0 (en) | 2013-05-20 | 2013-07-03 | Edixomed Ltd | Transdermal delivery system |
| US20170349438A1 (en) | 2016-06-06 | 2017-12-07 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| CA3052206A1 (en) * | 2017-02-20 | 2018-08-23 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Hydrogen sulfide and/or nitrite in the treatment and prevention of atrial fibrillation |
| US11850271B1 (en) * | 2023-05-16 | 2023-12-26 | King Faisal University | Topical skin cream |
| WO2026006722A1 (en) | 2024-06-28 | 2026-01-02 | The Regents Of The University Of Michigan | Nitric oxide generating medical devices and methods |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914446A (en) * | 1958-06-26 | 1959-11-24 | Upjohn Co | Nitrite stabilized ascorbic acid-cyanocobalamin compositions |
| US4650484A (en) | 1983-02-03 | 1987-03-17 | Alza Corporation | Method for treating ischemic conditions |
| IE64726B1 (en) | 1987-11-20 | 1995-08-23 | Elan Corp Plc | Pharmaceutical formulations for preventing drug tolerance |
| US5122384A (en) | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
| US5278192A (en) | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
| US6709681B2 (en) | 1995-02-17 | 2004-03-23 | Aberdeen University | Acidified nitrite as an antimicrobial agent |
| US20110196039A9 (en) * | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
| US5648101A (en) | 1994-11-14 | 1997-07-15 | Tawashi; Rashad | Drug delivery of nitric oxide |
| US5770645A (en) | 1996-08-02 | 1998-06-23 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| US5994444A (en) * | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
| US7371415B1 (en) | 1998-04-03 | 2008-05-13 | The Daily Wellness Company | Method and composition for improving sexual fitness |
| US7015876B1 (en) * | 1998-06-03 | 2006-03-21 | Lear Corporation | Heads-up display with improved contrast |
| EP1105146A1 (en) | 1998-07-14 | 2001-06-13 | Paracelsian, Inc. | Method for identifying and confirming consistent bio-functionality of natural compositions |
| AU764469B2 (en) | 1999-01-29 | 2003-08-21 | Disphar International B.V. | Pharmaceutical compositions |
| GB9905425D0 (en) | 1999-03-09 | 1999-05-05 | Queen Mary & Westfield College | Pharmaceutical composition |
| US6314956B1 (en) | 1999-09-08 | 2001-11-13 | Duke University | Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders |
| GB0119011D0 (en) * | 2001-08-03 | 2001-09-26 | Univ Aberdeen | Treatment of nail infections |
| EP1492509A1 (en) | 2001-12-18 | 2005-01-05 | ALZA Corporation | Dosage form providing time-varying patterns of drug delivery |
| EP1336602A1 (en) | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| EP1495026A4 (en) * | 2002-03-20 | 2008-07-09 | Univ Queensland | METHOD AND COMPOSITIONS CONTAINING STAIN OXIDE DISPENSERS AND OPIOLD ANALGETICS |
| CA2379211A1 (fr) | 2002-03-28 | 2003-09-28 | Institut De Cardiologie De Montreal | Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase) |
| JP5564157B2 (ja) | 2003-07-09 | 2014-07-30 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 心臓血管状態の処置のための亜硝酸塩の使用方法 |
| EP1670459A4 (en) | 2003-08-20 | 2009-03-25 | Nitromed Inc | NITROSED AND NITROSYLATED CARDIOVASCULAR COMPOUNDS, COMPOSITIONS AND APPLICATION METHODS |
| WO2005023189A2 (en) | 2003-09-03 | 2005-03-17 | Pharmacia Corporation | Method of cox-2 selective inhibitor and nitric oxide-donating agent |
| US7362274B1 (en) | 2004-07-09 | 2008-04-22 | Huan-Cheng Lien | Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna |
| US20060083824A1 (en) | 2004-10-20 | 2006-04-20 | Pbm Products Llc | Nutritional supplements for glucose intolerant individuals |
| EP1846058B1 (en) * | 2005-02-11 | 2009-07-15 | NOLabs AB | Device method, and use for treatment of neuropathy involving nitric oxide |
| BRPI0610180A2 (pt) | 2005-05-24 | 2012-09-25 | Wellgen Inc | métodos para prevenir, para tratar, e para tratar ou controlar uma condição associada à inflamação |
| NZ594596A (en) * | 2006-02-10 | 2011-10-28 | Mannatech Inc | All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization |
| GB0607402D0 (en) | 2006-04-12 | 2006-05-24 | Barts & London Nhs Trust | Therapeutic composition and use |
| WO2007149520A2 (en) | 2006-06-21 | 2007-12-27 | Albert Einstein College Of Medicine Of Yeshiva University | Compositions for sustained release of nitric oxide, methods of preparing same and uses thereof |
| JP2010519336A (ja) | 2007-02-26 | 2010-06-03 | ルンドベルク,ヨン | 亜硝酸塩及び硝酸塩及びこれらを含む組成物の新規使用 |
| PL2124638T3 (pl) | 2007-02-26 | 2017-07-31 | Heartbeet Ltd. | Kompozycja zwiększająca wydolność i jej zastosowanie |
| WO2008153762A2 (en) | 2007-05-25 | 2008-12-18 | N30 Pharmaceuticals, Llc | S-nitrosothiol formulations and storage systems |
| WO2009021058A2 (en) * | 2007-08-06 | 2009-02-12 | Trinity Labortories, Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
| CN101939014B (zh) | 2007-11-15 | 2016-04-27 | 路易斯安那州大学及农业和机械学院管理委员会 | 亚硝酸盐在慢性缺血中的应用 |
| US20090196930A1 (en) | 2007-12-27 | 2009-08-06 | Aires Pharmaceuticals, Inc. | Aerosolized nitrite and nitric oxide -donating compounds and uses thereof |
| WO2010036236A1 (en) | 2008-09-23 | 2010-04-01 | Baker Hughes Incorporated | Anchor assembly |
| US8568793B2 (en) * | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| WO2010147742A2 (en) | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| US20130209584A1 (en) | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| CA2777066C (en) * | 2009-10-14 | 2020-02-18 | TheraVasc, LLC | Pharmaceutical formulations of nitrite and uses thereof |
| WO2012135623A1 (en) | 2011-03-31 | 2012-10-04 | Theravasc Inc. | Use of nitrites for the treatment of cerebral amyloid angiopathy, age associated dementia, and cognitive decline |
| WO2012142413A2 (en) | 2011-04-14 | 2012-10-18 | Theravasc Inc. | Nitrite compositions and uses thereof |
| US9294956B2 (en) | 2011-12-29 | 2016-03-22 | Qualcomm Incorporated | Application-server-assisted preemptive multicast bearer establishment for real-time low-latency applications |
-
2010
- 2010-10-14 CA CA2777066A patent/CA2777066C/en active Active
- 2010-10-14 CN CN201710462544.3A patent/CN107260756A/zh active Pending
- 2010-10-14 IN IN3428DEN2012 patent/IN2012DN03428A/en unknown
- 2010-10-14 AU AU2010306755A patent/AU2010306755B2/en not_active Ceased
- 2010-10-14 ES ES10824097.9T patent/ES2633618T3/es active Active
- 2010-10-14 WO PCT/US2010/052683 patent/WO2011047161A1/en not_active Ceased
- 2010-10-14 JP JP2012534359A patent/JP5758904B2/ja not_active Expired - Fee Related
- 2010-10-14 US US12/904,791 patent/US10463689B2/en active Active
- 2010-10-14 CN CN2010800568984A patent/CN102686111A/zh active Pending
- 2010-10-14 EP EP10824097.9A patent/EP2488035B1/en active Active
-
2012
- 2012-04-15 IL IL219155A patent/IL219155A0/en unknown
-
2015
- 2015-06-04 JP JP2015113882A patent/JP6125567B2/ja not_active Expired - Fee Related
- 2015-09-08 US US14/847,966 patent/US10307441B2/en active Active
-
2017
- 2017-04-05 JP JP2017074888A patent/JP2017141275A/ja active Pending
-
2019
- 2019-10-11 US US16/599,710 patent/US20200085861A1/en not_active Abandoned
-
2020
- 2020-06-11 US US16/898,460 patent/US20200297756A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015180674A (ja) | 2015-10-15 |
| EP2488035A4 (en) | 2013-07-31 |
| US10463689B2 (en) | 2019-11-05 |
| AU2010306755A1 (en) | 2012-05-03 |
| ES2633618T3 (es) | 2017-09-22 |
| IN2012DN03428A (enExample) | 2015-10-23 |
| US20200297756A1 (en) | 2020-09-24 |
| JP6125567B2 (ja) | 2017-05-10 |
| JP2013508289A (ja) | 2013-03-07 |
| CN107260756A (zh) | 2017-10-20 |
| US20160067279A1 (en) | 2016-03-10 |
| CA2777066C (en) | 2020-02-18 |
| WO2011047161A1 (en) | 2011-04-21 |
| CN102686111A (zh) | 2012-09-19 |
| CA2777066A1 (en) | 2011-04-21 |
| US10307441B2 (en) | 2019-06-04 |
| JP5758904B2 (ja) | 2015-08-05 |
| US20110086069A1 (en) | 2011-04-14 |
| US20200085861A1 (en) | 2020-03-19 |
| EP2488035A1 (en) | 2012-08-22 |
| EP2488035B1 (en) | 2017-04-26 |
| JP2017141275A (ja) | 2017-08-17 |
| AU2010306755B2 (en) | 2015-12-24 |
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