JP5758904B2 - ニトライトの医薬製剤及びそれらの使用 - Google Patents

ニトライトの医薬製剤及びそれらの使用 Download PDF

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Publication number
JP5758904B2
JP5758904B2 JP2012534359A JP2012534359A JP5758904B2 JP 5758904 B2 JP5758904 B2 JP 5758904B2 JP 2012534359 A JP2012534359 A JP 2012534359A JP 2012534359 A JP2012534359 A JP 2012534359A JP 5758904 B2 JP5758904 B2 JP 5758904B2
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nitrite
pharmaceutical composition
composition according
pharmaceutically acceptable
formulation
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Japanese (ja)
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JP2013508289A5 (enExample
JP2013508289A (ja
Inventor
ケビル，クリストファー
ジョルダーノ，アンソニー
フラナガン，ダグラス，アール．
コンスタンティニデス，パナイオティス，ピー．
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セラバスク インコーポレーテッド
セラバスク インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012534359A 2009-10-14 2010-10-14 ニトライトの医薬製剤及びそれらの使用 Expired - Fee Related JP5758904B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25148309P 2009-10-14 2009-10-14
US61/251,483 2009-10-14
PCT/US2010/052683 WO2011047161A1 (en) 2009-10-14 2010-10-14 Pharmaceutical formulations of nitrite and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015113882A Division JP6125567B2 (ja) 2009-10-14 2015-06-04 ニトライトの医薬製剤及びそれらの使用

Publications (3)

Publication Number Publication Date
JP2013508289A JP2013508289A (ja) 2013-03-07
JP2013508289A5 JP2013508289A5 (enExample) 2013-10-31
JP5758904B2 true JP5758904B2 (ja) 2015-08-05

Family

ID=43855036

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012534359A Expired - Fee Related JP5758904B2 (ja) 2009-10-14 2010-10-14 ニトライトの医薬製剤及びそれらの使用
JP2015113882A Expired - Fee Related JP6125567B2 (ja) 2009-10-14 2015-06-04 ニトライトの医薬製剤及びそれらの使用
JP2017074888A Pending JP2017141275A (ja) 2009-10-14 2017-04-05 ニトライトの医薬製剤及びそれらの使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015113882A Expired - Fee Related JP6125567B2 (ja) 2009-10-14 2015-06-04 ニトライトの医薬製剤及びそれらの使用
JP2017074888A Pending JP2017141275A (ja) 2009-10-14 2017-04-05 ニトライトの医薬製剤及びそれらの使用

Country Status (10)

Country Link
US (4) US10463689B2 (enExample)
EP (1) EP2488035B1 (enExample)
JP (3) JP5758904B2 (enExample)
CN (2) CN107260756A (enExample)
AU (1) AU2010306755B2 (enExample)
CA (1) CA2777066C (enExample)
ES (1) ES2633618T3 (enExample)
IL (1) IL219155A0 (enExample)
IN (1) IN2012DN03428A (enExample)
WO (1) WO2011047161A1 (enExample)

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BR112014003414B1 (pt) * 2011-08-17 2021-09-21 Board Of Regents, The University Of Texas System Composição e sistema de entrega oral para aumento de níveis fisiológicos e terapêuticos de óxido nítrico
US8627204B2 (en) * 2011-10-18 2014-01-07 Microsoft Corporation Custom optimization of web pages
CN105358160A (zh) 2013-02-20 2016-02-24 瑟阿瓦斯克公司 亚硝酸盐的药物制剂及其用途
WO2014183108A1 (en) * 2013-05-10 2014-11-13 Nitromega Corp. Nutritional or dietary supplements containing fatty acids and nitrite
GB201309092D0 (en) * 2013-05-20 2013-07-03 Edixomed Ltd Transdermal delivery system
WO2017214157A1 (en) 2016-06-06 2017-12-14 Theravasc Inc. Pharmaceutical formulations of nitrite uses thereof
IL268804B2 (en) 2017-02-20 2023-04-01 Univ Louisiana State Hydrogen sulfide and/or nitrite for the treatment and prevention of atrial fibrillation
US11850271B1 (en) * 2023-05-16 2023-12-26 King Faisal University Topical skin cream
WO2026006722A1 (en) 2024-06-28 2026-01-02 The Regents Of The University Of Michigan Nitric oxide generating medical devices and methods

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US5278192A (en) * 1992-07-02 1994-01-11 The Research Foundation Of State University Of New York Method of vasodilator therapy for treating a patient with a condition
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US20110196039A9 (en) * 1994-10-05 2011-08-11 Kaesemeyer Wayne H Controlled release arginine formulations
US5648101A (en) * 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
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CA2379211A1 (fr) * 2002-03-28 2003-09-28 Institut De Cardiologie De Montreal Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase)
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Also Published As

Publication number Publication date
AU2010306755B2 (en) 2015-12-24
IN2012DN03428A (enExample) 2015-10-23
CN102686111A (zh) 2012-09-19
CA2777066A1 (en) 2011-04-21
US10463689B2 (en) 2019-11-05
JP2017141275A (ja) 2017-08-17
US20200085861A1 (en) 2020-03-19
CN107260756A (zh) 2017-10-20
JP6125567B2 (ja) 2017-05-10
JP2015180674A (ja) 2015-10-15
US10307441B2 (en) 2019-06-04
US20110086069A1 (en) 2011-04-14
IL219155A0 (en) 2012-06-28
AU2010306755A1 (en) 2012-05-03
US20200297756A1 (en) 2020-09-24
EP2488035A4 (en) 2013-07-31
US20160067279A1 (en) 2016-03-10
JP2013508289A (ja) 2013-03-07
ES2633618T3 (es) 2017-09-22
EP2488035A1 (en) 2012-08-22
CA2777066C (en) 2020-02-18
WO2011047161A1 (en) 2011-04-21
EP2488035B1 (en) 2017-04-26

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