IN2012DN02695A - - Google Patents
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- Publication number
- IN2012DN02695A IN2012DN02695A IN2695DEN2012A IN2012DN02695A IN 2012DN02695 A IN2012DN02695 A IN 2012DN02695A IN 2695DEN2012 A IN2695DEN2012 A IN 2695DEN2012A IN 2012DN02695 A IN2012DN02695 A IN 2012DN02695A
- Authority
- IN
- India
- Prior art keywords
- pyrimidin
- hydroxy
- reacting
- butyl
- methyl
- Prior art date
Links
- OAMDXZTUOHORAO-UHFFFAOYSA-N 2-(2-butyl-6-methyl-4-oxo-1h-pyrimidin-5-yl)-n,n-dimethylacetamide Chemical compound CCCCC1=NC(=O)C(CC(=O)N(C)C)=C(C)N1 OAMDXZTUOHORAO-UHFFFAOYSA-N 0.000 abstract 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- RSZXNWVCAXONHY-UHFFFAOYSA-N 2-(2-butyl-6-methyl-4-oxo-1h-pyrimidin-5-yl)acetic acid Chemical compound CCCCC1=NC(=O)C(CC(O)=O)=C(C)N1 RSZXNWVCAXONHY-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- LPXCHPSTROLSJX-UHFFFAOYSA-N pentanimidamide Chemical compound CCCCC(N)=N LPXCHPSTROLSJX-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20100005725 | 2010-01-21 | ||
| KR20100005945A KR101058284B1 (ko) | 2010-01-22 | 2010-01-22 | 2-(2-ｎ-부틸-4-히드록시-6-메틸-피리미딘-5-일)-Ｎ,Ｎ-디메틸아세트아미드의 신규한 제조방법 |
| PCT/KR2011/000401 WO2011090323A2 (en) | 2010-01-21 | 2011-01-20 | Novel preparation method of 2-(2-n-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl)-n,n-dimethylacetamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02695A true IN2012DN02695A (enrdf_load_stackoverflow) | 2015-09-04 |
Family
ID=44307398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2695DEN2012 IN2012DN02695A (enrdf_load_stackoverflow) | 2010-01-21 | 2011-01-20 |
Country Status (3)
| Country | Link |
|---|---|
| CN (2) | CN102666496B (enrdf_load_stackoverflow) |
| IN (1) | IN2012DN02695A (enrdf_load_stackoverflow) |
| WO (1) | WO2011090323A2 (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140096514A (ko) * | 2013-01-28 | 2014-08-06 | 보령제약 주식회사 | 암 예방 또는 치료용 조성물 |
| CN110123771A (zh) | 2013-03-14 | 2019-08-16 | 保宁制药株式会社 | 药物组合药物 |
| CN104478811B (zh) * | 2014-11-14 | 2017-01-25 | 浙江浙邦制药有限公司 | 一种非马沙坦中间体的制备方法 |
| CN107973784B (zh) * | 2017-11-16 | 2021-08-24 | 珠海市海瑞德生物科技有限公司 | 一种非马沙坦的合成方法 |
| CN113121484A (zh) * | 2019-12-31 | 2021-07-16 | 复星弘创(苏州)医药科技有限公司 | 一种制备3-位被酰胺基烷基取代的香豆素类化合物的方法及其产物和相关中间体 |
| CN113336709B (zh) * | 2021-06-25 | 2022-06-03 | 上海立科化学科技有限公司 | 一种n,n-二甲基乙酰胺的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR19990081093A (ko) * | 1998-04-25 | 1999-11-15 | 조생현 | 피리미디논 화합물, 이를 함유하는 약제학적 조성물 및 이의제조방법 |
| DE60132637T2 (de) * | 2001-09-21 | 2009-01-15 | Boryung Pharmaceutical Co., Ltd. | Verfahren zum herstellen von pyrimidionverbindungen und deren pharmazeutisch unbedenklichen salzen |
| KR100521980B1 (ko) * | 2002-10-10 | 2005-10-17 | 보령제약 주식회사 | 피리미디논 화합물 및 이의 염의 삼수화물의 제조 방법 |
-
2011
- 2011-01-20 IN IN2695DEN2012 patent/IN2012DN02695A/en unknown
- 2011-01-20 CN CN201180004629.8A patent/CN102666496B/zh not_active Expired - Fee Related
- 2011-01-20 WO PCT/KR2011/000401 patent/WO2011090323A2/en active Application Filing
- 2011-01-20 CN CN201410817307.0A patent/CN104610164B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN104610164A (zh) | 2015-05-13 |
| CN102666496A (zh) | 2012-09-12 |
| CN102666496B (zh) | 2015-05-20 |
| WO2011090323A2 (en) | 2011-07-28 |
| WO2011090323A3 (en) | 2011-11-10 |
| CN104610164B (zh) | 2018-03-16 |
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