IN2012DN02454A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02454A
IN2012DN02454A IN2454DEN2012A IN2012DN02454A IN 2012DN02454 A IN2012DN02454 A IN 2012DN02454A IN 2454DEN2012 A IN2454DEN2012 A IN 2454DEN2012A IN 2012DN02454 A IN2012DN02454 A IN 2012DN02454A
Authority
IN
India
Prior art keywords
colistin
ethanol concentration
eluting
purifying
loading
Prior art date
Application number
Other languages
English (en)
Inventor
Torben Koch
Carsten Overballe-Petersen
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Publication of IN2012DN02454A publication Critical patent/IN2012DN02454A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN2454DEN2012 2009-10-30 2010-09-29 IN2012DN02454A (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25634409P 2009-10-30 2009-10-30
PCT/EP2010/064472 WO2011051070A1 (en) 2009-10-30 2010-09-29 Method for purification of colistin and purified colistin components

Publications (1)

Publication Number Publication Date
IN2012DN02454A true IN2012DN02454A (sl) 2015-08-21

Family

ID=42983681

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2454DEN2012 IN2012DN02454A (sl) 2009-10-30 2010-09-29

Country Status (16)

Country Link
US (1) US9005990B2 (sl)
EP (1) EP2470555B1 (sl)
JP (1) JP5882219B2 (sl)
KR (1) KR20120112437A (sl)
CN (1) CN102596987B (sl)
AU (1) AU2010311759B2 (sl)
CA (1) CA2777112A1 (sl)
DK (1) DK2470555T3 (sl)
ES (1) ES2532408T3 (sl)
HR (1) HRP20150283T1 (sl)
IL (1) IL219348A (sl)
IN (1) IN2012DN02454A (sl)
PL (1) PL2470555T3 (sl)
PT (1) PT2470555E (sl)
SI (1) SI2470555T1 (sl)
WO (1) WO2011051070A1 (sl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116161962A (zh) * 2023-02-06 2023-05-26 中国科学院上海硅酸盐研究所 一种具有各向异性电学性能的碳化硅压敏陶瓷及其制备方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201522364A (zh) * 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉（ｃｍｓ）之定性方法
CN103993059B (zh) * 2014-05-28 2016-08-17 河北圣雪大成制药有限责任公司 优化多粘芽孢杆菌发酵液中e1和e2组分比例的方法
CA2949328C (en) 2014-07-09 2023-01-31 Xellia Pharmaceuticals Aps Low substituted polymyxins and compositions thereof
PL3200762T3 (pl) 2014-10-03 2019-08-30 Xellia Pharmaceuticals Aps Urządzenie do inhalacji
EP3200827B1 (en) 2014-10-03 2020-08-12 Xellia Pharmaceuticals ApS Compositions
WO2016166103A1 (en) 2015-04-13 2016-10-20 Xellia Pharmaceuticals Aps Polymyxin derivatives
CN108226315B (zh) * 2016-12-15 2022-04-12 上海医药工业研究院 一种检测多黏菌素e残留量的分析方法
PL239311B1 (pl) * 2018-02-28 2021-11-22 Tarchomińskie Zakłady Farmaceutyczne Polfa Spółka Akcyjna Sposób izolowania czystego składnika siarczanu polimyksyny E

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20907A (en) 1858-07-13 Refrigerator
GR6498B (el) 1937-05-11 1937-05-12 Ισιδωρος Τρατσης Συστημα λειτουργιας επι των εξωτερικων παραθυρων δια την προστασιαν εκ της εισοδου των κωνωπων.
WO1998020836A2 (en) * 1996-11-15 1998-05-22 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
SE0300612D0 (sv) * 2003-03-05 2003-03-05 Amersham Biosciences Ab A method of preparing ligands for hydrophobic interaction chromatography
US7413658B2 (en) * 2003-11-21 2008-08-19 Akzo Nobel N.V. Separation method
JP5030586B2 (ja) * 2004-05-26 2012-09-19 味の素株式会社 アミノ官能性化合物の分析方法及び装置
WO2007071767A1 (en) * 2005-12-23 2007-06-28 Novo Nordisk Health Care Ag Purification of vitamin k-dependent polypeptides using preparative reverse phase chromatography (rpc)
CN101525377B (zh) * 2008-03-07 2013-04-03 上海医药工业研究院 一种多黏菌素e甲磺酸钠的分离纯化方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116161962A (zh) * 2023-02-06 2023-05-26 中国科学院上海硅酸盐研究所 一种具有各向异性电学性能的碳化硅压敏陶瓷及其制备方法

Also Published As

Publication number Publication date
HRP20150283T1 (hr) 2015-04-10
JP2013509365A (ja) 2013-03-14
PL2470555T3 (pl) 2015-05-29
WO2011051070A1 (en) 2011-05-05
AU2010311759A1 (en) 2012-04-19
KR20120112437A (ko) 2012-10-11
CN102596987A (zh) 2012-07-18
EP2470555B1 (en) 2014-12-24
ES2532408T3 (es) 2015-03-26
SI2470555T1 (sl) 2015-04-30
PT2470555E (pt) 2015-03-23
US20120208981A1 (en) 2012-08-16
IL219348A0 (en) 2012-06-28
EP2470555A1 (en) 2012-07-04
AU2010311759B2 (en) 2015-09-24
US9005990B2 (en) 2015-04-14
JP5882219B2 (ja) 2016-03-09
DK2470555T3 (en) 2015-04-07
CN102596987B (zh) 2014-06-25
CA2777112A1 (en) 2011-05-05
IL219348A (en) 2016-11-30

Similar Documents

Publication Publication Date Title
IN2012DN02454A (sl)
EP2448048A4 (en) Gas diffusion electrode and production method for same; membrane electrode assembly and production method for same
ZA201104944B (en) Two-stage process for biomass pretreatment
HK1159632A1 (en) Novel phenylimidazole derivatives as pde10a enzyme inhibitors pde10a
WO2010020766A3 (en) Interleukin fusion polypeptides
HUE047178T2 (hu) Gázdiffúziós elektród, továbbá eljárás annak gyártására
MX2012002565A (es) Purificacion de proteina mejorada a traves de una elucion de proteina a modificada.
WO2009024726A3 (fr) Procede de purification ou de detection d'une proteine cible
SG157326A1 (en) Method for aging alcoholic liquids
HUP0402444A2 (en) Process for enhancing the biogas production of thermophyl anaerobic fermenter
MY172018A (en) Strains and method for the production of methionine
EP2346522A4 (en) PROCESS FOR MODULATING PROTEIN HOMEOSTASIS, METABOLISM SYNDROME, HEAVY METAL POISONING AND NRF2 TRANSCRIPTION FACTORS
ZA200808568B (en) Process for increasing the oxidation stability of biodiesel
RS57450B1 (sr) Postupak za proizvodnju kvasca sa visokim sadržajem glutaminske kiseline
EA201101597A1 (ru) Системы и способы для сокращения выбросов ртути
EP2270145A4 (en) NEW HYALURONIC ACID BINDING PROTEIN AND METHOD FOR MEASURING HYALURONIC ACID THEREFOR
EP2447344A4 (en) DIESEL COMPOSITION AND METHOD FOR IMPROVING THE OXIDATION STABILITY OF BIODIESEL
EP2330186A4 (en) METHOD OF SYNTHESIZING A HIGH PROTEIN AMINO ACID PROTEIN BY SIMULTANEOUS EXPRESSION WITH SPECIFIC AMINO ACID TRANSFER RNA (ARNT)
WO2013074816A3 (en) Novel inhibitors of nox1
ZA201004697B (en) Evaporator of vinasse concentration for distilleries in general
UA34487U (en) Aquananomagnesium
CY1116136T1 (el) Μεθοδος καθαρισμου κολιστινης και κεκαθαρμενες ενωσεις κολιστινης
CL2013003596A1 (es) Metodo para la purificacion de anticuerpos a partir de una mezcla de proteínas producidas en un biorreactor que comprende una cromatografia de intercambio iónico; unidad operativa que puede usarse con el metodo antes indicado.
WO2012051323A3 (en) Cryptophane derivatives and methods of use thereof
EA201291308A1 (ru) Способ производства спирта