IN2012DN02454A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02454A
IN2012DN02454A IN2454DEN2012A IN2012DN02454A IN 2012DN02454 A IN2012DN02454 A IN 2012DN02454A IN 2454DEN2012 A IN2454DEN2012 A IN 2454DEN2012A IN 2012DN02454 A IN2012DN02454 A IN 2012DN02454A
Authority
IN
India
Prior art keywords
colistin
ethanol concentration
eluting
purifying
loading
Prior art date
Application number
Other languages
English (en)
Inventor
Torben Koch
Carsten Overballe-Petersen
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Publication of IN2012DN02454A publication Critical patent/IN2012DN02454A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62Polymyxins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN2454DEN2012 2009-10-30 2010-09-29 IN2012DN02454A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25634409P 2009-10-30 2009-10-30
PCT/EP2010/064472 WO2011051070A1 (en) 2009-10-30 2010-09-29 Method for purification of colistin and purified colistin components

Publications (1)

Publication Number Publication Date
IN2012DN02454A true IN2012DN02454A (ja) 2015-08-21

Family

ID=42983681

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2454DEN2012 IN2012DN02454A (ja) 2009-10-30 2010-09-29

Country Status (16)

Country Link
US (1) US9005990B2 (ja)
EP (1) EP2470555B1 (ja)
JP (1) JP5882219B2 (ja)
KR (1) KR20120112437A (ja)
CN (1) CN102596987B (ja)
AU (1) AU2010311759B2 (ja)
CA (1) CA2777112A1 (ja)
DK (1) DK2470555T3 (ja)
ES (1) ES2532408T3 (ja)
HR (1) HRP20150283T1 (ja)
IL (1) IL219348A (ja)
IN (1) IN2012DN02454A (ja)
PL (1) PL2470555T3 (ja)
PT (1) PT2470555E (ja)
SI (1) SI2470555T1 (ja)
WO (1) WO2011051070A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116161962A (zh) * 2023-02-06 2023-05-26 中国科学院上海硅酸盐研究所 一种具有各向异性电学性能的碳化硅压敏陶瓷及其制备方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201522364A (zh) * 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉(cms)之定性方法
CN103993059B (zh) * 2014-05-28 2016-08-17 河北圣雪大成制药有限责任公司 优化多粘芽孢杆菌发酵液中e1和e2组分比例的方法
KR20170032348A (ko) 2014-07-09 2017-03-22 셀리아 파마슈티칼즈 에이피에스 저 치환된 폴리믹신 및 이의 조성물
EP3520777B1 (en) 2014-10-03 2020-09-30 Xellia Pharmaceuticals ApS Inhalation device
SG11201702717XA (en) 2014-10-03 2017-04-27 Xellia Pharmaceuticals Aps Compositions
WO2016166103A1 (en) 2015-04-13 2016-10-20 Xellia Pharmaceuticals Aps Polymyxin derivatives
CN108226315B (zh) * 2016-12-15 2022-04-12 上海医药工业研究院 一种检测多黏菌素e残留量的分析方法
PL239311B1 (pl) * 2018-02-28 2021-11-22 Tarchomińskie Zakłady Farmaceutyczne Polfa Spółka Akcyjna Sposób izolowania czystego składnika siarczanu polimyksyny E
CN115010788B (zh) * 2022-05-10 2024-06-28 倪京满 N-末端脂肪酸修饰的具有抗生物膜活性的低毒广谱抗菌肽类似物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20907A (en) 1858-07-13 Refrigerator
GR6498B (el) 1937-05-11 1937-05-12 Ισιδωρος Τρατσης Συστημα λειτουργιας επι των εξωτερικων παραθυρων δια την προστασιαν εκ της εισοδου των κωνωπων.
JP2001505557A (ja) * 1996-11-15 2001-04-24 パソジェネシス コーポレイション 肺感染を処置するための、純粋な生物学的活性コリスチン、その成分、およびコリスチン処方物
SE0300612D0 (sv) * 2003-03-05 2003-03-05 Amersham Biosciences Ab A method of preparing ligands for hydrophobic interaction chromatography
US7413658B2 (en) * 2003-11-21 2008-08-19 Akzo Nobel N.V. Separation method
WO2005116629A1 (ja) * 2004-05-26 2005-12-08 Ajinomoto Co., Inc. アミノ官能性化合物の分析方法及び装置
WO2007071767A1 (en) * 2005-12-23 2007-06-28 Novo Nordisk Health Care Ag Purification of vitamin k-dependent polypeptides using preparative reverse phase chromatography (rpc)
CN101525377B (zh) 2008-03-07 2013-04-03 上海医药工业研究院 一种多黏菌素e甲磺酸钠的分离纯化方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116161962A (zh) * 2023-02-06 2023-05-26 中国科学院上海硅酸盐研究所 一种具有各向异性电学性能的碳化硅压敏陶瓷及其制备方法

Also Published As

Publication number Publication date
EP2470555A1 (en) 2012-07-04
IL219348A (en) 2016-11-30
HRP20150283T1 (hr) 2015-04-10
PT2470555E (pt) 2015-03-23
AU2010311759B2 (en) 2015-09-24
DK2470555T3 (en) 2015-04-07
JP2013509365A (ja) 2013-03-14
US20120208981A1 (en) 2012-08-16
SI2470555T1 (sl) 2015-04-30
EP2470555B1 (en) 2014-12-24
CN102596987A (zh) 2012-07-18
AU2010311759A1 (en) 2012-04-19
JP5882219B2 (ja) 2016-03-09
ES2532408T3 (es) 2015-03-26
KR20120112437A (ko) 2012-10-11
CN102596987B (zh) 2014-06-25
PL2470555T3 (pl) 2015-05-29
IL219348A0 (en) 2012-06-28
US9005990B2 (en) 2015-04-14
WO2011051070A1 (en) 2011-05-05
CA2777112A1 (en) 2011-05-05

Similar Documents

Publication Publication Date Title
IN2012DN02454A (ja)
EP2336347A4 (en) L-amino acid-producing microorganism and method for producing L-amino acid
EP2448048A4 (en) Gas diffusion electrode and production method for same; membrane electrode assembly and production method for same
ZA201104944B (en) Two-stage process for biomass pretreatment
ZA201100109B (en) Novel phenylimidazole derivatives as pde10a enzyme inhibitors
WO2010020766A3 (en) Interleukin fusion polypeptides
HUE047178T2 (hu) Gázdiffúziós elektród, továbbá eljárás annak gyártására
MX2012002565A (es) Purificacion de proteina mejorada a traves de una elucion de proteina a modificada.
MY172018A (en) Strains and method for the production of methionine
WO2009024726A3 (fr) Procede de purification ou de detection d'une proteine cible
SG157326A1 (en) Method for aging alcoholic liquids
HUP0402444A2 (en) Process for enhancing the biogas production of thermophyl anaerobic fermenter
EP2346522A4 (en) PROCESS FOR MODULATING PROTEIN HOMEOSTASIS, METABOLISM SYNDROME, HEAVY METAL POISONING AND NRF2 TRANSCRIPTION FACTORS
ZA200808568B (en) Process for increasing the oxidation stability of biodiesel
PL3385369T3 (pl) Sposób wytwarzania drożdży o wysokiej zawartości kwasu glutaminowego
EP2276776A4 (en) METHOD AND AFFINITY COLUMN FOR PURIFYING PROTEINS
EA201101597A1 (ru) Системы и способы для сокращения выбросов ртути
IN2014DN10038A (ja)
EP2447344A4 (en) DIESEL COMPOSITION AND METHOD FOR IMPROVING THE OXIDATION STABILITY OF BIODIESEL
WO2013074816A3 (en) Novel inhibitors of nox1
EP2177592A4 (en) ODORANT GAS SUBSTANCE AND PROCESS FOR PRODUCING CITY GAS COMPRISING SAID ODOR SUBSTANCE
ZA201004697B (en) Evaporator of vinasse concentration for distilleries in general
UA34487U (en) Aquananomagnesium
CY1116136T1 (el) Μεθοδος καθαρισμου κολιστινης και κεκαθαρμενες ενωσεις κολιστινης
CL2013003596A1 (es) Metodo para la purificacion de anticuerpos a partir de una mezcla de proteínas producidas en un biorreactor que comprende una cromatografia de intercambio iónico; unidad operativa que puede usarse con el metodo antes indicado.