IN2012DN02396A - - Google Patents
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- Publication number
- IN2012DN02396A IN2012DN02396A IN2396DEN2012A IN2012DN02396A IN 2012DN02396 A IN2012DN02396 A IN 2012DN02396A IN 2396DEN2012 A IN2396DEN2012 A IN 2396DEN2012A IN 2012DN02396 A IN2012DN02396 A IN 2012DN02396A
- Authority
- IN
- India
- Prior art keywords
- isobutanol
- cells
- isolation
- observed
- developed
- Prior art date
Links
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 abstract 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000003855 L-lactate dehydrogenase Human genes 0.000 abstract 1
- 108700023483 L-lactate dehydrogenases Proteins 0.000 abstract 1
- 108010084631 acetolactate decarboxylase Proteins 0.000 abstract 1
- 230000006696 biosynthetic metabolic pathway Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000012407 engineering method Methods 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01054—Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01005—Acetolactate decarboxylase (4.1.1.5)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24671709P | 2009-09-29 | 2009-09-29 | |
| PCT/US2010/050705 WO2011041402A1 (en) | 2009-09-29 | 2010-09-29 | Improved flux to acetolactate-derived products in lactic acid bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02396A true IN2012DN02396A (show.php) | 2015-08-21 |
Family
ID=43093547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2396DEN2012 IN2012DN02396A (show.php) | 2009-09-29 | 2010-09-29 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9169499B2 (show.php) |
| EP (1) | EP2483400A1 (show.php) |
| JP (1) | JP2013505739A (show.php) |
| CN (1) | CN102712912A (show.php) |
| AU (1) | AU2010300722A1 (show.php) |
| BR (1) | BR112012006941A2 (show.php) |
| CA (1) | CA2776151A1 (show.php) |
| IN (1) | IN2012DN02396A (show.php) |
| WO (1) | WO2011041402A1 (show.php) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| MX2009008416A (es) | 2007-02-09 | 2010-01-25 | Univ California | Produccion de biocombustible mediante microorganismos recombinantes. |
| JP5582576B2 (ja) | 2007-04-18 | 2014-09-03 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| KR20110063576A (ko) | 2008-09-29 | 2011-06-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 효모에서 증가된 이종성 Ｆｅ-Ｓ 효소 활성 |
| WO2011041426A1 (en) * | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Improved yeast production host cells |
| CA2784903A1 (en) | 2009-12-29 | 2011-07-28 | Butamax(Tm) Advanced Biofuels Llc | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| WO2011082248A1 (en) | 2009-12-29 | 2011-07-07 | Butamax(Tm) Advanced Biofuels Llc | Expression of hexose kinase in recombinant host cells |
| MX348605B (es) | 2010-02-17 | 2017-06-21 | Butamax(Tm) Advanced Biofuels Llc | Mejoramiento de la actividad de proteinas que requieren centros fe-s. |
| NZ722791A (en) | 2010-09-07 | 2018-12-21 | Butamax Tm Advanced Biofuels | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| KR20140092759A (ko) | 2011-03-24 | 2014-07-24 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 숙주 세포 및 아이소부탄올의 제조 방법 |
| US8889383B2 (en) | 2011-04-29 | 2014-11-18 | Danisco Us Inc. | Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, HMG-CoA synthase and HMG-CoA reductase enzymatic activities |
| MX2014000966A (es) | 2011-07-28 | 2014-07-09 | Butamax Advanced Biofuels Llc | Enzimas cetoisovalerato descarboxilasa y metodos de uso de las mismas. |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| CN102559736B (zh) * | 2012-02-24 | 2014-01-08 | 常茂生物化学工程股份有限公司 | 提高富马酸产量的基因工程菌株及构建方法及其应用 |
| KR20140146616A (ko) | 2012-03-23 | 2014-12-26 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 부타놀로겐용 배지의 아세테이트 보충물 |
| NZ701099A (en) | 2012-05-11 | 2017-04-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| CN102816787B (zh) * | 2012-06-20 | 2015-05-06 | 江南大学 | 利用重组大肠杆菌高效表达Staphyloccocus aureus α-乙酰乳酸脱羧酶 |
| WO2014025604A2 (en) * | 2012-08-07 | 2014-02-13 | Gevo, Inc. | Microorganisms for improved production of fuels, chemicals, and amino acids |
| BR112015003701A2 (pt) | 2012-08-22 | 2017-12-12 | Butamax Advanced Biofuels Llc | células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição |
| CN102876704A (zh) * | 2012-09-20 | 2013-01-16 | 江南大学 | 利用重组枯草芽孢杆菌高效表达Staphyloccocus aureus α-乙酰乳酸脱羧酶 |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| CN105102616A (zh) | 2012-09-26 | 2015-11-25 | 布特马斯先进生物燃料有限责任公司 | 具有酮醇酸还原异构酶活性的多肽 |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
| US9441250B2 (en) | 2013-03-14 | 2016-09-13 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
| US20150122558A1 (en) | 2013-09-09 | 2015-05-07 | Columbia Trailer Co., Inc. | Lifting jack assembly with rotatable hydraulic cylinder for steering and method of operation |
| WO2015076393A1 (ja) * | 2013-11-22 | 2015-05-28 | 旭硝子株式会社 | 形質転換体およびその製造方法、ならびに乳酸の製造方法 |
| US10280438B2 (en) | 2014-08-11 | 2019-05-07 | Butamax Advanced Biofuels Llc | Method for the production of yeast |
| EP3309247A4 (en) * | 2015-06-12 | 2019-01-09 | Cj Cheiljedang Corporation | MICROORGANISM HAVING IMPROVED LACTIC ACID PRODUCTION AND METHOD FOR PRODUCING LACTIC ACID USING THE SAME |
| WO2017060455A1 (en) * | 2015-10-09 | 2017-04-13 | Danmarks Tekniske Universitet | High-level production of diacetyl in a metabolically engineered lactic acid bacterium |
| KR20190104342A (ko) | 2016-12-14 | 2019-09-09 | 바게닝겐 유니버시테이트 | 열안정성 cas9 뉴클레아제 |
| CN108570438B (zh) * | 2017-03-08 | 2020-06-30 | 中国科学院上海高等研究院 | 提升克雷伯氏肺炎杆菌生产α-酮异戊酸的方法及改造菌 |
| CN108486176B (zh) * | 2018-05-18 | 2021-08-03 | 天津科技大学 | 一种产乳酸乙酯的酿酒酵母及其构建方法与应用 |
| IT201800007846A1 (it) * | 2018-08-03 | 2020-02-03 | Università Degli Studi Di Milano - Bicocca | Procedimento per la biosintesi cellulare di acido poli d-lattico e di acido poli l-lattico |
| US20220152126A1 (en) * | 2019-02-01 | 2022-05-19 | Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement | Lactococcus lactis strains for the prevention and/or the treatment of visceral pain |
| CN111893083A (zh) * | 2019-05-05 | 2020-11-06 | 中国科学院上海高等研究院 | 改造的克雷伯氏属细菌及其生产2,3-二羟基异戊酸的应用 |
| CN114457122B (zh) * | 2020-05-13 | 2023-06-20 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组微生物及构建方法、应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US6645754B1 (en) * | 1996-08-22 | 2003-11-11 | Chr. Hansen A/S | Metabolically engineered lactic acid bacteria and their use |
| FR2777905B1 (fr) | 1998-04-23 | 2002-07-19 | Agronomique Inst Nat Rech | Bacteries surproductrices d'alpha-acetolactate, et procede d'obtention |
| DE19855312A1 (de) | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
| WO2004105518A1 (en) | 2003-05-22 | 2004-12-09 | Hilltop Ranch, Inc. | Apparatus and process for almond pasteurization |
| TWI348262B (en) | 2005-02-10 | 2011-09-01 | Bruno Ferrario | A circuit and method for adaptive frequency compensation for dc-to-dc converter |
| BRPI0612944B1 (pt) | 2005-04-12 | 2017-11-28 | E.I.Du Pont De Nemours And Company | Method of production of target substance |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| UA96928C2 (ru) | 2005-10-26 | 2011-12-26 | Э.И. Дю Пон Де Немур Энд Компани | Ферментативное продуцирование спиртов с четырьмя атомами углерода |
| US8956850B2 (en) | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
| JP5582576B2 (ja) | 2007-04-18 | 2014-09-03 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 |
| US8130756B2 (en) | 2007-07-13 | 2012-03-06 | Hewlett-Packard Development Company, L.P. | Tunnel configuration associated with packet checking in a network |
| ES2575413T3 (es) | 2007-12-20 | 2016-06-28 | Butamax (Tm) Advanced Biofuels Llc | Cetol-ácido reductoisomerasa que utiliza NADH |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8828695B2 (en) | 2008-06-04 | 2014-09-09 | Butamax Advanced Biofuels Llc | Method for producing butanol using two-phase extractive fermentation |
| EP2331683A1 (en) | 2008-09-29 | 2011-06-15 | Butamax Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| BRPI0913547A2 (pt) | 2008-09-29 | 2020-08-18 | Butamax Advanced Biofuels Llc | célula bacteriana ácido-lática recombinante, método para a produção de 2-butanol e método para a produção de 2-butanona |
| US20100081182A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
| BRPI0914521A2 (pt) | 2008-10-27 | 2016-07-26 | Butamax Advanced Biofuels Llc | célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol |
| US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| ES2773130T3 (es) | 2014-06-18 | 2020-07-09 | Fotona D O O | Cabeza de tratamiento láser y sistema láser |
| US10078608B2 (en) | 2016-09-16 | 2018-09-18 | Intel Corporation | USB-C multiple connector support for host and device mode configurations |
-
2010
- 2010-09-29 CA CA2776151A patent/CA2776151A1/en not_active Abandoned
- 2010-09-29 CN CN2010800539407A patent/CN102712912A/zh active Pending
- 2010-09-29 WO PCT/US2010/050705 patent/WO2011041402A1/en not_active Ceased
- 2010-09-29 BR BR112012006941A patent/BR112012006941A2/pt not_active IP Right Cessation
- 2010-09-29 US US12/893,065 patent/US9169499B2/en active Active
- 2010-09-29 EP EP10760890A patent/EP2483400A1/en not_active Withdrawn
- 2010-09-29 AU AU2010300722A patent/AU2010300722A1/en not_active Abandoned
- 2010-09-29 JP JP2012532272A patent/JP2013505739A/ja active Pending
- 2010-09-29 IN IN2396DEN2012 patent/IN2012DN02396A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2776151A1 (en) | 2011-04-07 |
| AU2010300722A1 (en) | 2012-04-12 |
| JP2013505739A (ja) | 2013-02-21 |
| EP2483400A1 (en) | 2012-08-08 |
| WO2011041402A1 (en) | 2011-04-07 |
| CN102712912A (zh) | 2012-10-03 |
| US20110136192A1 (en) | 2011-06-09 |
| US9169499B2 (en) | 2015-10-27 |
| BR112012006941A2 (pt) | 2015-09-08 |
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