IN2012DN02073A - - Google Patents

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Publication number
IN2012DN02073A
IN2012DN02073A IN2073DEN2012A IN2012DN02073A IN 2012DN02073 A IN2012DN02073 A IN 2012DN02073A IN 2073DEN2012 A IN2073DEN2012 A IN 2073DEN2012A IN 2012DN02073 A IN2012DN02073 A IN 2012DN02073A
Authority
IN
India
Prior art keywords
hcg
including recombinant
preparations including
preparations
recombinant hcg
Prior art date
Application number
Other languages
English (en)
Inventor
Ian Cottingham
Daniel Plaksin
Richard Boyd White
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of IN2012DN02073A publication Critical patent/IN2012DN02073A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/99Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN2073DEN2012 2009-10-05 2010-10-04 IN2012DN02073A (show.php)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09252360 2009-10-05
PCT/GB2010/001854 WO2011042688A1 (en) 2009-10-05 2010-10-04 Pharmaceutical preparation comprising recombinant hcg

Publications (1)

Publication Number Publication Date
IN2012DN02073A true IN2012DN02073A (show.php) 2015-08-21

Family

ID=41471027

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2073DEN2012 IN2012DN02073A (show.php) 2009-10-05 2010-10-04

Country Status (25)

Country Link
US (5) US8975226B2 (show.php)
EP (2) EP2486051B1 (show.php)
JP (6) JP6176924B2 (show.php)
KR (7) KR20170133531A (show.php)
CN (1) CN107050434B (show.php)
AR (2) AR079876A1 (show.php)
AU (1) AU2010304922B2 (show.php)
BR (1) BR112012007990A2 (show.php)
CA (1) CA2776790A1 (show.php)
DK (1) DK2486051T3 (show.php)
ES (2) ES2798258T3 (show.php)
HR (1) HRP20200941T1 (show.php)
HU (1) HUE050793T2 (show.php)
IL (3) IL218548A (show.php)
IN (1) IN2012DN02073A (show.php)
JO (1) JOP20200039A1 (show.php)
LT (1) LT2486051T (show.php)
MX (1) MX2012003951A (show.php)
PL (1) PL2486051T3 (show.php)
PT (1) PT2486051T (show.php)
RS (1) RS60413B1 (show.php)
RU (2) RU2588650C2 (show.php)
SI (1) SI2486051T1 (show.php)
TW (2) TWI532495B (show.php)
WO (1) WO2011042688A1 (show.php)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI488640B (zh) 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
ES2693273T3 (es) * 2011-03-31 2018-12-10 Ferring B.V. Preparación farmacéutica
WO2012168680A1 (en) * 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
AU2012340501A1 (en) * 2011-12-19 2013-07-11 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
US10144923B2 (en) 2012-12-10 2018-12-04 Seikagaku Corporation Recombinant Factor C and method for producing the same, and method for measuring endotoxin
JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Cmp依存性シアリダーゼ活性
HUE051879T2 (hu) * 2015-04-24 2021-03-29 Ferring Bv Eljárás gonadotrofin elõállítására
WO2016207353A1 (en) 2015-06-26 2016-12-29 Ferring B.V. Methods of purification and/or viral inactivation
HUE071268T2 (hu) * 2018-04-30 2025-08-28 Ferring Bv Készítmény szabályozott petefészek-stimuláláshoz
KR20220137651A (ko) * 2020-02-05 2022-10-12 노파르티스 아게 Il-15 이종이량체를 발현하는 cho 세포
CN116199742B (zh) * 2022-07-06 2025-01-24 华兰基因工程有限公司 一种重组人绒毛膜促性腺激素Fc融合蛋白制备方法

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IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
UA61053C2 (en) * 1995-03-21 2003-11-17 Applied Research Systems Stable liquid pharmaceutical compositions, method for its production and delivery form
IL122732A0 (en) * 1997-01-15 1998-08-16 Akzo Nobel Nv Liquid gonadotropin-containing formulation its preparation and a device containing same
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US6500627B1 (en) * 1998-02-03 2002-12-31 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by HCG assay
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UA87433C2 (ru) * 2001-10-22 2009-07-27 Еплайд Рісьорч Системз Ерс Холдінг Н.В. Гонадотропины для стимулирования фолликулогенеза
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KR100809945B1 (ko) * 2006-02-01 2008-03-05 대한민국 인체장내정상세균총 특이반응 dna칩 및 이를 이용한인체장내정상세균총의 변화에 의한 인체 위해성의 평가방법
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TWI488640B (zh) * 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
ES2693273T3 (es) * 2011-03-31 2018-12-10 Ferring B.V. Preparación farmacéutica
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض

Also Published As

Publication number Publication date
US20130023476A1 (en) 2013-01-24
EP3611185B1 (en) 2025-04-30
IL250733B (en) 2019-07-31
US20200247863A1 (en) 2020-08-06
US20140249082A1 (en) 2014-09-04
MX2012003951A (es) 2012-05-29
JP6310440B2 (ja) 2018-04-11
KR20190028823A (ko) 2019-03-19
US12234272B2 (en) 2025-02-25
US20220340634A1 (en) 2022-10-27
RS60413B1 (sr) 2020-07-31
JP7292153B2 (ja) 2023-06-16
JOP20200039A1 (ar) 2022-10-30
IL218548A0 (en) 2012-05-31
JP7196244B2 (ja) 2022-12-26
AU2010304922B2 (en) 2014-11-06
KR101987982B1 (ko) 2019-06-11
KR101804479B1 (ko) 2017-12-05
JP2016074680A (ja) 2016-05-12
WO2011042688A1 (en) 2011-04-14
TW201632198A (zh) 2016-09-16
JP6176924B2 (ja) 2017-08-09
CN107050434B (zh) 2021-07-27
HRP20200941T1 (hr) 2020-09-18
CN102549011A (zh) 2012-07-04
TW201113030A (en) 2011-04-16
AU2010304922A1 (en) 2012-03-29
US20180030107A1 (en) 2018-02-01
KR102489143B1 (ko) 2023-01-13
JP2023075144A (ja) 2023-05-30
JP2018076296A (ja) 2018-05-17
HUE050793T2 (hu) 2021-01-28
LT2486051T (lt) 2020-07-10
ES2798258T3 (es) 2020-12-10
AR079876A1 (es) 2012-02-29
EP2486051A1 (en) 2012-08-15
JP6580104B2 (ja) 2019-09-25
KR20120094909A (ko) 2012-08-27
TWI604850B (zh) 2017-11-11
KR20210014767A (ko) 2021-02-09
RU2016118236A3 (show.php) 2019-09-18
IL267556A (en) 2019-08-29
SI2486051T1 (sl) 2020-08-31
TWI532495B (zh) 2016-05-11
US8975226B2 (en) 2015-03-10
KR20190067256A (ko) 2019-06-14
KR20230012104A (ko) 2023-01-25
CA2776790A1 (en) 2011-04-14
DK2486051T3 (da) 2020-06-22
EP3611185A1 (en) 2020-02-19
JP2020000246A (ja) 2020-01-09
KR20170133531A (ko) 2017-12-05
PL2486051T3 (pl) 2020-09-07
US11292824B2 (en) 2022-04-05
JP2013506708A (ja) 2013-02-28
RU2012112907A (ru) 2013-11-10
RU2588650C2 (ru) 2016-07-10
RU2016118236A (ru) 2018-10-29
ES3036152T3 (en) 2025-09-15
US9676835B2 (en) 2017-06-13
BR112012007990A2 (pt) 2017-07-25
JP2021176867A (ja) 2021-11-11
IL218548A (en) 2017-03-30
KR102213154B1 (ko) 2021-02-05
US10526390B2 (en) 2020-01-07
PT2486051T (pt) 2020-06-17
KR20210141771A (ko) 2021-11-23
IL250733A0 (en) 2017-04-30
EP2486051B1 (en) 2020-03-25
RU2724528C2 (ru) 2020-06-23
CN107050434A (zh) 2017-08-18
AR125991A2 (es) 2023-08-30

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