IN2012DN02064A - - Google Patents

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Publication number
IN2012DN02064A
IN2012DN02064A IN2064DEN2012A IN2012DN02064A IN 2012DN02064 A IN2012DN02064 A IN 2012DN02064A IN 2064DEN2012 A IN2064DEN2012 A IN 2064DEN2012A IN 2012DN02064 A IN2012DN02064 A IN 2012DN02064A
Authority
IN
India
Prior art keywords
representing
cr2r3
crl
linker
bio
Prior art date
Application number
Other languages
English (en)
Inventor
Laurence Moine
Laurent Bedouet
Alexandre Laurent
Denis Labarre
Michel Wassef
Van Nga Nguyen
Original Assignee
Occlugel
Centre Nat Rech Scient
Univ Paris Sud 11
Assist Publ Hopitaux De Paris
Univ Paris Diderot Paris 7
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Occlugel, Centre Nat Rech Scient, Univ Paris Sud 11, Assist Publ Hopitaux De Paris, Univ Paris Diderot Paris 7 filed Critical Occlugel
Publication of IN2012DN02064A publication Critical patent/IN2012DN02064A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/061—Polyesters; Polycarbonates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F299/00—Macromolecular compounds obtained by interreacting polymers involving only carbon-to-carbon unsaturated bond reactions, in the absence of non-macromolecular monomers
    • C08F299/02—Macromolecular compounds obtained by interreacting polymers involving only carbon-to-carbon unsaturated bond reactions, in the absence of non-macromolecular monomers from unsaturated polycondensates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L55/00—Compositions of homopolymers or copolymers, obtained by polymerisation reactions only involving carbon-to-carbon unsaturated bonds, not provided for in groups C08L23/00 - C08L53/00
    • C08L55/005—Homopolymers or copolymers obtained by polymerisation of macromolecular compounds terminated by a carbon-to-carbon double bond
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Graft Or Block Polymers (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
IN2064DEN2012 2009-09-10 2010-09-09 IN2012DN02064A (enrdf_load_stackoverflow)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09305830A EP2295480A1 (en) 2009-09-10 2009-09-10 Implantable bio-resorbable polymer
PCT/EP2010/063227 WO2011029867A1 (en) 2009-09-10 2010-09-09 Implantable bio-resorbable polymer
US24118310P 2010-09-10 2010-09-10

Publications (1)

Publication Number Publication Date
IN2012DN02064A true IN2012DN02064A (enrdf_load_stackoverflow) 2015-08-21

Family

ID=41531626

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2064DEN2012 IN2012DN02064A (enrdf_load_stackoverflow) 2009-09-10 2010-09-09

Country Status (13)

Country Link
US (1) US9320804B2 (enrdf_load_stackoverflow)
EP (2) EP2295480A1 (enrdf_load_stackoverflow)
JP (1) JP5792729B2 (enrdf_load_stackoverflow)
KR (1) KR101585588B1 (enrdf_load_stackoverflow)
CN (1) CN102597030B (enrdf_load_stackoverflow)
AU (1) AU2010294246B2 (enrdf_load_stackoverflow)
BR (1) BR112012005280B8 (enrdf_load_stackoverflow)
CA (1) CA2773499C (enrdf_load_stackoverflow)
ES (1) ES2472426T3 (enrdf_load_stackoverflow)
IN (1) IN2012DN02064A (enrdf_load_stackoverflow)
SG (1) SG179057A1 (enrdf_load_stackoverflow)
WO (1) WO2011029867A1 (enrdf_load_stackoverflow)
ZA (1) ZA201201752B (enrdf_load_stackoverflow)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8921429B2 (en) * 2010-11-23 2014-12-30 Howard University Biodegradable stealth polymeric particles fabricated using the macromonomer approach by free radical dispersion polymerization
AU2012224524B2 (en) 2011-03-09 2016-03-31 Assistance Publique - Hopitaux De Paris Implantable swellable bio-resorbable polymer
EP2683753B1 (en) 2011-03-09 2016-08-03 Occlugel Implantable bio-resorbable polymer charged with fragile macromolecules
CN102304200B (zh) * 2011-05-27 2013-08-21 中国海洋石油总公司 一种交联聚合物微球及其制备方法
CN103709386B (zh) * 2012-10-09 2016-03-30 上海微创医疗器械（集团）有限公司 改性聚乳酸可降解支架及其制备方法
CN103113533B (zh) * 2013-02-01 2015-08-05 中国科学院长春应用化学研究所 聚乳酸共聚物及其制备方法、改性聚乳酸
CN105814120B (zh) * 2013-09-19 2019-07-05 泰尔茂株式会社 聚合物颗粒
BR112016005768B1 (pt) 2013-09-19 2021-09-21 Microvention, Inc Películas de polímero
AU2014346486B2 (en) 2013-11-08 2016-12-08 Terumo Corporation Polymer particles
CN105214145A (zh) * 2014-06-23 2016-01-06 李茂全 聚乳酸微球在出血性疾病中的应用
FR3024732B1 (fr) * 2014-08-08 2016-08-12 Snf Sas Polymere hydroxyalkyle hydrosoluble obtenu par procede de polymerisation en suspension inverse ou emulsion inverse
CN104558419B (zh) * 2014-09-27 2017-07-11 温州大学 一种环境敏感型环糊精衍生物水凝胶的制备方法
US9907880B2 (en) 2015-03-26 2018-03-06 Microvention, Inc. Particles
US12115289B2 (en) 2016-02-05 2024-10-15 The General Hospital Corporation Drug eluting polymer composed of biodegradable polymers applied to surface of medical device
US10376469B2 (en) 2016-02-17 2019-08-13 Biosphere Medical, Inc. Microspheres containing therapeutic agents and related methods of use
JP7130561B2 (ja) * 2016-06-23 2022-09-05 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト ナノゲルによるポリマーネットワーク構造の制御
EP3518994B1 (en) 2016-09-28 2024-02-07 Terumo Corporation Polymer particles
CN106543992A (zh) * 2016-09-30 2017-03-29 成都西油华巍科技有限公司 一种钻井液用聚合物微球封堵剂及其制备方法
WO2019035975A1 (en) * 2017-08-16 2019-02-21 Biosphere Medical, Inc. MICROSPHERES CONTAINING THERAPEUTIC AGENTS AND ASSOCIATED METHODS OF USE
CN111150879B (zh) * 2019-12-31 2022-06-17 华中科技大学鄂州工业技术研究院 一种促凝血和x光显影栓塞剂及其制备方法和应用
WO2022047544A1 (en) * 2020-09-04 2022-03-10 IP Cornerstone Pty Ltd Minimally invasive treatment of osteoarthritis and other conditions
CN112934198B (zh) * 2021-01-29 2022-07-08 浙江理工大学 一种环糊精多孔吸附材料及其制备方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0131112D0 (en) 2001-12-31 2002-02-13 Univ London Pharmacy Block copolymers
WO2005079856A1 (en) * 2004-02-23 2005-09-01 The University Of British Columbia Drug delivery compositions comprising hydrophobic polymers and amphipathic molecules
JP2005330246A (ja) * 2004-05-21 2005-12-02 Toray Ind Inc 膨潤性ヒドロゲルマトリックスを含む医薬組成物
WO2006045183A1 (en) * 2004-10-25 2006-05-04 The University Of British Columbia Polymer barrier compositions for surgical wounds
EP1904932A4 (en) * 2005-06-17 2013-02-27 Univ North Carolina METHODS, SYSTEMS AND MATERIALS FOR THE MANUFACTURE OF NANOPARTICLES
FI20060077A7 (fi) * 2006-01-26 2007-07-27 Jvs Polymers Oy Biohajoavien polymeerien käyttö
WO2009132206A1 (en) * 2008-04-25 2009-10-29 Liquidia Technologies, Inc. Compositions and methods for intracellular delivery and release of cargo
CN101265311A (zh) * 2008-05-07 2008-09-17 天津大学 Pvp-peg-pla壳层交联的纳米胶束的制备方法

Also Published As

Publication number Publication date
KR20120099006A (ko) 2012-09-06
SG179057A1 (en) 2012-04-27
JP2013504538A (ja) 2013-02-07
AU2010294246A1 (en) 2012-04-05
JP5792729B2 (ja) 2015-10-14
BR112012005280B1 (pt) 2021-10-05
US9320804B2 (en) 2016-04-26
WO2011029867A1 (en) 2011-03-17
EP2475695B1 (en) 2014-04-02
EP2295480A1 (en) 2011-03-16
US20120230937A1 (en) 2012-09-13
KR101585588B1 (ko) 2016-01-14
BR112012005280A2 (pt) 2020-10-27
CA2773499A1 (en) 2011-03-17
CN102597030B (zh) 2013-11-06
ES2472426T3 (es) 2014-07-01
AU2010294246B2 (en) 2014-12-04
EP2475695A1 (en) 2012-07-18
CN102597030A (zh) 2012-07-18
BR112012005280B8 (pt) 2021-10-26
CA2773499C (en) 2017-12-05
ZA201201752B (en) 2012-11-28

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