IN2012DN00862A - - Google Patents

Download PDF

Info

Publication number
IN2012DN00862A
IN2012DN00862A IN862DEN2012A IN2012DN00862A IN 2012DN00862 A IN2012DN00862 A IN 2012DN00862A IN 862DEN2012 A IN862DEN2012 A IN 862DEN2012A IN 2012DN00862 A IN2012DN00862 A IN 2012DN00862A
Authority
IN
India
Prior art keywords
ring
present
provides
lactone
novel
Prior art date
Application number
Other languages
English (en)
Inventor
Megan Alene Foley
Timothy F Jamison
Oljan Repic
Original Assignee
Novartis Ag
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Massachusetts Inst Technology filed Critical Novartis Ag
Publication of IN2012DN00862A publication Critical patent/IN2012DN00862A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/14Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN862DEN2012 2009-08-11 2010-08-11 IN2012DN00862A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23288609P 2009-08-11 2009-08-11
US23288009P 2009-08-11 2009-08-11
PCT/US2010/045121 WO2011019789A1 (en) 2009-08-11 2010-08-11 The ring opening of lactones and lactams

Publications (1)

Publication Number Publication Date
IN2012DN00862A true IN2012DN00862A (ru) 2015-07-10

Family

ID=42813428

Family Applications (1)

Application Number Title Priority Date Filing Date
IN862DEN2012 IN2012DN00862A (ru) 2009-08-11 2010-08-11

Country Status (12)

Country Link
US (1) US8779198B2 (ru)
EP (1) EP2464623B1 (ru)
JP (1) JP5746696B2 (ru)
KR (1) KR101755052B1 (ru)
CN (1) CN102686556A (ru)
AU (1) AU2010282623B2 (ru)
BR (1) BR112012003255B1 (ru)
CA (1) CA2769186C (ru)
IN (1) IN2012DN00862A (ru)
MX (3) MX344328B (ru)
RU (1) RU2550691C2 (ru)
WO (1) WO2011019789A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2551260A1 (en) 2011-07-28 2013-01-30 Chemo Ibérica, S.A. Chemical process for opening ring compounds
CN102351734B (zh) * 2011-09-05 2014-02-26 浙江普洛医药科技有限公司 一种阿利克仑的制备方法
US8703976B2 (en) 2011-10-02 2014-04-22 Milan Soukup Manufacturing process for 8-aryloctanoic acids such as Aliskiren
CN108940117B (zh) * 2018-08-03 2020-07-24 郑州轻工业学院 一种含羟基联接基团的非离子糖基型双子表面活性剂及其制备方法
CN110452231B (zh) * 2019-08-16 2023-03-28 上海应用技术大学 一种色氨酸类化合物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4729985A (en) * 1985-08-09 1988-03-08 Pfizer Inc. Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
EP0236734A3 (de) 1986-02-07 1988-05-11 Ciba-Geigy Ag Durch schwefelhaltigen Gruppen substituierte 5-Amino-4-hydroxyvalerylderivate
MY119161A (en) 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US20060154926A1 (en) * 2002-06-11 2006-07-13 Elan Pharmaceuticals, Inc. Methods of treating alzheimer's disease using aryl alkanoic acid amides
EP1689702B1 (en) * 2003-11-26 2013-01-30 Novartis AG Organic compounds
GB0419361D0 (en) * 2004-08-31 2004-10-06 Novartis Ag Organic compounds
GB0511686D0 (en) * 2005-06-08 2005-07-13 Novartis Ag Organic compounds
GB0521083D0 (en) * 2005-10-17 2005-11-23 Novartis Ag Organic compounds
GB0605780D0 (en) * 2006-03-22 2006-05-03 Syngenta Ltd Formulations
CN101679213A (zh) * 2007-04-03 2010-03-24 诺瓦提斯公司 新方法

Also Published As

Publication number Publication date
AU2010282623B2 (en) 2013-12-12
BR112012003255B1 (pt) 2018-10-23
CA2769186A1 (en) 2011-02-17
MX2012001850A (es) 2012-03-07
RU2550691C2 (ru) 2015-05-10
KR20120054628A (ko) 2012-05-30
MX347956B (es) 2017-05-16
US8779198B2 (en) 2014-07-15
JP2013501797A (ja) 2013-01-17
AU2010282623A1 (en) 2012-02-23
CN102686556A (zh) 2012-09-19
EP2464623B1 (en) 2020-11-04
BR112012003255A8 (pt) 2016-05-17
CA2769186C (en) 2016-10-04
MX344328B (es) 2016-12-13
US20120165555A1 (en) 2012-06-28
RU2012108932A (ru) 2013-09-20
KR101755052B1 (ko) 2017-07-06
WO2011019789A1 (en) 2011-02-17
JP5746696B2 (ja) 2015-07-08
EP2464623A1 (en) 2012-06-20
BR112012003255A2 (pt) 2016-03-01

Similar Documents

Publication Publication Date Title
UA110199C2 (en) Solid rifaximin dispersion
TW200608973A (en) Rapamycin polymorph Ⅱ and uses thereof
UA97502C2 (ru) Кристаллическая твердая основа разагилина
MX342643B (es) Formas de dosificacion farmaceutica que comprenden poli (e-caprolactona).
WO2008151170A3 (en) Process for the synthesis of ramelteon and its intermediates
MY162411A (en) Crystalline forms of a macrolide, and uses therefor
WO2009135646A3 (en) Stable pharmaceutical compositions and their processes for preparation suitable for industrial scale
MY140739A (en) 2, 6-quinolinyl derivatives, processes for preparing them and their uses
WO2011019986A3 (en) Processes for preparing pemetrexed
MX2009013354A (es) Compuestos de triarilo y composiciones que los contienen.
MX2011008621A (es) Proceso para la purificacion de lipopeptidos.
IN2012DN02793A (ru)
IN2012DN00862A (ru)
TW200702331A (en) Process for preparing alkylanilides
WO2009137714A3 (en) Forms of lapatinib ditosylate and processes for preparation thereof
GB201303865D0 (en) Pharmaceutical composition and method of inhibiting of production or amplifyingelimination of P24 protein
MX339461B (es) Polipeptidos y composiciones inmunizantes que contienen polipeptidos grampositivos y metodos de uso.
WO2010119450A3 (en) An improved process for the preparation of desmopressin or its pharmaceutically acceptable salts
MX2009013921A (es) Material refractario sin forma, un proceso para producir un material refractario sin forma, humedo como la tierra, y al uso del material refractario sin forma.
WO2010059916A3 (en) Preparation of docetaxel
PL2091478T3 (pl) Opakowanie prezerwatyw
MX2010003056A (es) Polimorfos de valomaciclovir.
ZA200903193B (en) Novel Morphine derivatives
JO2857B1 (en) Vinyl pipers with modified activity of tumor-resistant TNF
MX2009006748A (es) Proceso para la preparacion y aislamiento de los estereoisomeros individuales de fenilciclopentan-carboxilatos 3-sustituidos de 1-amino.