IN2012DE00661A - - Google Patents
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- Publication number
- IN2012DE00661A IN2012DE00661A IN661DE2012A IN2012DE00661A IN 2012DE00661 A IN2012DE00661 A IN 2012DE00661A IN 661DE2012 A IN661DE2012 A IN 661DE2012A IN 2012DE00661 A IN2012DE00661 A IN 2012DE00661A
- Authority
- IN
- India
- Prior art keywords
- substituted
- hetero
- aminoquinoline
- aryl
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/382,727 US9567316B2 (en) | 2012-03-07 | 2013-02-28 | Aminoquinoline derivatives and uses thereof |
EP21194376.6A EP3971178A1 (fr) | 2012-03-07 | 2013-02-28 | Dérivés d'aminoquinoléine et leurs utilisations |
PT137586780T PT2822936T (pt) | 2012-03-07 | 2013-02-28 | Derivados da aminoquinolina e suas utilizações |
ES13758678T ES2899730T3 (es) | 2012-03-07 | 2013-02-28 | Derivados de la aminoquinolina y sus usos |
PCT/US2013/028329 WO2013134047A2 (fr) | 2012-03-07 | 2013-02-28 | Dérivés d'aminoquinoléine et leurs utilisations |
EP13758678.0A EP2822936B1 (fr) | 2012-03-07 | 2013-02-28 | Dérivés d'aminoquinoléine et leurs utilisations |
IN661DE2012 IN2012DE00661A (fr) | 2012-03-07 | 2013-02-28 | |
US15/404,964 US11026943B2 (en) | 2012-03-07 | 2017-01-12 | Aminoquinoline derivatives and uses thereof |
US17/240,886 US20220008418A1 (en) | 2012-03-07 | 2021-04-26 | Aminoquinoline Derivatives and Uses Thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN661DE2012 IN2012DE00661A (fr) | 2012-03-07 | 2013-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DE00661A true IN2012DE00661A (fr) | 2015-08-21 |
Family
ID=49117483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN661DE2012 IN2012DE00661A (fr) | 2012-03-07 | 2013-02-28 |
Country Status (6)
Country | Link |
---|---|
US (3) | US9567316B2 (fr) |
EP (2) | EP3971178A1 (fr) |
ES (1) | ES2899730T3 (fr) |
IN (1) | IN2012DE00661A (fr) |
PT (1) | PT2822936T (fr) |
WO (1) | WO2013134047A2 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10144932B2 (en) * | 2014-06-06 | 2018-12-04 | Board Of Trustees Of Michigan State University | Nurr1 as a genetic target for treating levodopa-induced dyskinesias in Parkinson's disease |
CN104070943B (zh) * | 2014-07-23 | 2017-10-17 | 万通智控科技股份有限公司 | 一种自编程轮胎压力监测装置及实现方法 |
WO2016111957A1 (fr) * | 2015-01-06 | 2016-07-14 | Albert Einstein College Of Medicine, Inc. | Composés triazole de chloroquinoline, composition et utilisations |
CN107249588A (zh) | 2015-02-16 | 2017-10-13 | 浦项工科大学校产学协力团 | 包含阿莫地喹作为有效成分的代谢性疾病的预防、改善或治疗用组合物 |
US10329258B2 (en) | 2015-04-30 | 2019-06-25 | University Of Washington | CGAS in systemic lupus erythematosus (SLE) |
EP3307072A4 (fr) | 2015-06-15 | 2019-04-03 | Mayo Foundation for Medical Education and Research | Utilisation de cellules souches mésenchymateuses autologues pour traiter l'atrophie multisystémique |
CN105301126B (zh) * | 2015-10-10 | 2021-02-12 | 大道隆达(北京)医药科技发展有限公司 | 一种托匹司他有关物质的分析方法 |
EP3498279A4 (fr) | 2016-08-12 | 2020-04-29 | Novmetapharma Co., Ltd. | Composition pharmaceutique comprenant comme principes actifs de l'amodiaquine et un médicament anti-diabète, destinée à la prévention ou le traitement du diabète |
AU2019288490A1 (en) * | 2018-06-21 | 2020-12-03 | Nevada Research & Innovation Corporation | Disease modifying methods for treating neurodegenerative diseases using nootropic agents |
CN109620971A (zh) * | 2018-12-14 | 2019-04-16 | 昆明医科大学第附属医院 | 一种筛选防治帕金森病药物的方法 |
BR112022003025A2 (pt) * | 2019-08-22 | 2022-05-10 | Biohaven Therapeutics Ltd | Moléculas que se ligam a tdp-43 para o tratamento de esclerose lateral amiotrófica e distúrbios relacionados |
WO2021087077A1 (fr) * | 2019-10-29 | 2021-05-06 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Inhibiteurs à petites molécules d'autophagie et d'histone désacétylase et leurs utilisations |
CA3175047A1 (fr) * | 2020-07-07 | 2022-01-13 | The Mclean Hospital Corporation | Composes et methodes de traitement de maladies neurodegeneratives |
WO2022178338A2 (fr) * | 2021-02-20 | 2022-08-25 | Biohaven Therapeutics Ltd. | Petites molécules qui se lient à la tdp-43 pour le traitement de la sla et de troubles apparentés |
WO2023159062A2 (fr) * | 2022-02-15 | 2023-08-24 | University Of Central Florida Research Foundation, Inc. | Medicaments anaboliques stimulant la production de collagene de type ii à partir de chondrocytes ou de leurs progeniteurs |
WO2024049718A2 (fr) * | 2022-08-31 | 2024-03-07 | Immunocure Inc. | Dérivés de quinoléine pipérazine, composition pharmaceutique et leurs utilisations |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE626239A (fr) | 1961-12-29 | 1900-01-01 | ||
US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4044126A (en) | 1972-04-20 | 1977-08-23 | Allen & Hanburys Limited | Steroidal aerosol compositions and process for the preparation thereof |
GB1429184A (en) | 1972-04-20 | 1976-03-24 | Allen & Hanburys Ltd | Physically anti-inflammatory steroids for use in aerosols |
USRE28819E (en) | 1972-12-08 | 1976-05-18 | Syntex (U.S.A.) Inc. | Dialkylated glycol compositions and medicament preparations containing same |
US4410545A (en) | 1981-02-13 | 1983-10-18 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
US4328245A (en) | 1981-02-13 | 1982-05-04 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
US4358603A (en) | 1981-04-16 | 1982-11-09 | Syntex (U.S.A.) Inc. | Acetal stabilized prostaglandin compositions |
US4409239A (en) | 1982-01-21 | 1983-10-11 | Syntex (U.S.A.) Inc. | Propylene glycol diester solutions of PGE-type compounds |
US4487761A (en) | 1982-04-05 | 1984-12-11 | Merck & Co., Inc. | Dopamine β-hydroxylase inhibitors |
US4992459A (en) | 1983-04-12 | 1991-02-12 | Smithkline Beecham Corporation | Dopamine-β-hydroxylase inhibitors |
US4906668A (en) | 1984-08-23 | 1990-03-06 | Georgia Tech Research Corporation | Aminoalkyl phenyl selenides for the treatment of hypertension and nervous system dysfunctions |
US4634711A (en) | 1985-08-02 | 1987-01-06 | Smithkline Beckman Corporation | Pyridylalkyl imidazole-2-thiols |
US4719223A (en) | 1985-10-31 | 1988-01-12 | Smithkline Beckman Corporation | Imidazolethiol dopamine-beta-hydroxylase inhibitors |
US4743613A (en) | 1986-04-08 | 1988-05-10 | Smithkline Beckman Corporation | Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity |
US4810800A (en) | 1986-05-06 | 1989-03-07 | Merrell Dow Pharmaceuticals Inc. | Novel imidazole dopamine beta hydroxylase inhibitors |
US5189052A (en) | 1986-05-06 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | Thione dopamine beta hydroxylase inhibitors |
US4761415A (en) | 1986-08-28 | 1988-08-02 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4749717A (en) | 1987-01-08 | 1988-06-07 | Smithkline Beckman Corporation | Dopamine-beta-hydroxylase inhibitors |
US4859779A (en) | 1987-03-24 | 1989-08-22 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4762850A (en) | 1987-03-24 | 1988-08-09 | Smithkline Beckman Corporation | Dopamine-beta-hydroxylase inhibitors |
US4835154A (en) | 1987-06-01 | 1989-05-30 | Smithkline Beckman Corporation | 1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors |
US4798843A (en) | 1987-07-09 | 1989-01-17 | Smithkline Beckman Corporation | 2-mercaproimidazole dopamine-β-hydroxylase inhibitors |
US4839371A (en) | 1987-09-17 | 1989-06-13 | Smithkline Beckman Corporation | 3-aralkyl-2-mercaptoyridines as dopamine-β-hydroxylase inhibitors |
US4882348A (en) | 1987-12-29 | 1989-11-21 | Smithkline Beckman Corporation | 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors |
US4935438A (en) | 1987-12-29 | 1990-06-19 | Smithkline Beckman Corporation | Dopamine-β-hydroxylase inhibitors |
US4876266A (en) | 1987-12-31 | 1989-10-24 | Smithkline Beckman Corporation | 1-aralkyl-2-mercaptoimidazolines as DBH inhibitors |
US5994392A (en) | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
US4935449A (en) | 1988-08-04 | 1990-06-19 | Merrell Dow Pharmaceuticals Inc. | N-2,3-butadienyl tri- and tetraaminoalkane derivatives |
US4963568A (en) | 1989-05-31 | 1990-10-16 | Abbott Laboratories | Dopamine agonists |
US5100912A (en) | 1990-05-14 | 1992-03-31 | Syntex (U.S.A.) Inc. | Bis(benzylpyrrolidine) derivatives as dopamine agonists |
US5108899A (en) | 1989-10-31 | 1992-04-28 | Exoxemis, Inc. | Chemiluminescence assay of in vivo inflammation |
US6559186B1 (en) | 1990-02-26 | 2003-05-06 | Arc 1, Inc. | Compositions and methods of treatment of sympathetically maintained pain |
CN1046723C (zh) | 1993-04-06 | 1999-11-24 | 艾博特公司 | 四环化合物、含有它们的药物组合物及其用途 |
US5550139A (en) | 1994-01-03 | 1996-08-27 | The Wichita State University | Serine protease inhibitors |
US5925567A (en) | 1995-05-19 | 1999-07-20 | T. Breeders, Inc. | Selective expansion of target cell populations |
EP0934249B1 (fr) | 1996-10-18 | 2002-03-27 | Wisconsin Alumni Research Foundation | Polyamines de conformation restreinte et leur utilisation en tant qu'agents antineoplasiques |
US5889061A (en) | 1997-10-15 | 1999-03-30 | Wisconsin Alumni Research Foundation | Conformationally restricted polyamines |
US7410798B2 (en) | 2001-01-10 | 2008-08-12 | Geron Corporation | Culture system for rapid expansion of human embryonic stem cells |
EA004656B1 (ru) | 1999-04-01 | 2004-06-24 | Пфайзер Продактс Инк. | Аминопиримидины в качестве ингибиторов сорбитолдегидрогеназы |
CA2368801A1 (fr) | 1999-04-30 | 2000-11-09 | Slil Biomedical Corporation | Nouveaux conjugues d'analogue de polyamine et conjugues de quinone, utilises pour le traitement de cancers et de maladies de la prostate |
CA2371625C (fr) | 1999-04-30 | 2012-04-17 | Slil Biomedical Corporation | Analogues de polyamine a conformation restreinte utilises pour traiter des maladies |
US7455983B2 (en) | 2000-01-11 | 2008-11-25 | Geron Corporation | Medium for growing human embryonic stem cells |
CA2417064A1 (fr) | 2000-08-02 | 2002-02-07 | Slil Biomedical Corporation | Composes de polyamine cyclique pour la cancerotherapie |
WO2003012040A2 (fr) | 2001-07-27 | 2003-02-13 | Baylor College Of Medecine | Gene nurr1 mutant implique dans la maladie de parkinson |
US6818772B2 (en) * | 2002-02-22 | 2004-11-16 | Abbott Laboratories | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor |
WO2003070244A1 (fr) | 2002-02-22 | 2003-08-28 | Abbott Laboratories | Antagoniste des effets d'une hormone de concentration de melanine et son utilisation |
RU2005102004A (ru) * | 2002-06-27 | 2005-10-20 | Шеринг Акциенгезельшафт (De) | Замещенные хинолины как антагонисты рецептора ccr5 |
US7899888B2 (en) * | 2002-06-28 | 2011-03-01 | Oracle America, Inc. | Runtime versioning of information processing systems |
US7125904B2 (en) | 2002-10-11 | 2006-10-24 | Portela & C.A., S.A. | Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation |
US7323462B2 (en) | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
EP1635763B1 (fr) | 2003-06-09 | 2012-08-08 | Alnylam Pharmaceuticals Inc. | Procede de traitement de maladie neurodegenerative |
JP2009527478A (ja) * | 2006-02-16 | 2009-07-30 | ザ マクレーン ホスピタル コーポレーション | パーキンソン病の治療のための方法と組成物 |
WO2008036374A2 (fr) * | 2006-09-21 | 2008-03-27 | Medistem Laboratories, Inc. | Allogreffes de cellules souches chez des receveurs non conditionnes |
US20110045100A1 (en) | 2008-03-05 | 2011-02-24 | Georgetown University | Antimalarial Quinolines and Methods of Use Thereof |
US8628962B2 (en) | 2008-11-18 | 2014-01-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Differentiation of stem cells into dopaminergic cells |
US8658648B2 (en) * | 2008-12-05 | 2014-02-25 | Designmedix, Inc. | Modified chloroquines with single ring moiety or fused ring moiety |
-
2013
- 2013-02-28 IN IN661DE2012 patent/IN2012DE00661A/en unknown
- 2013-02-28 WO PCT/US2013/028329 patent/WO2013134047A2/fr active Application Filing
- 2013-02-28 EP EP21194376.6A patent/EP3971178A1/fr active Pending
- 2013-02-28 EP EP13758678.0A patent/EP2822936B1/fr active Active
- 2013-02-28 US US14/382,727 patent/US9567316B2/en active Active
- 2013-02-28 ES ES13758678T patent/ES2899730T3/es active Active
- 2013-02-28 PT PT137586780T patent/PT2822936T/pt unknown
-
2017
- 2017-01-12 US US15/404,964 patent/US11026943B2/en active Active
-
2021
- 2021-04-26 US US17/240,886 patent/US20220008418A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
PT2822936T (pt) | 2021-12-02 |
US20220008418A1 (en) | 2022-01-13 |
WO2013134047A2 (fr) | 2013-09-12 |
US20170209441A1 (en) | 2017-07-27 |
EP3971178A1 (fr) | 2022-03-23 |
US11026943B2 (en) | 2021-06-08 |
EP2822936B1 (fr) | 2021-09-08 |
ES2899730T3 (es) | 2022-03-14 |
WO2013134047A3 (fr) | 2013-10-31 |
US9567316B2 (en) | 2017-02-14 |
EP2822936A2 (fr) | 2015-01-14 |
US20150023930A1 (en) | 2015-01-22 |
EP2822936A4 (fr) | 2016-04-20 |
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