IN2012DE00289A - - Google Patents
Info
- Publication number
- IN2012DE00289A IN2012DE00289A IN289DE2012A IN2012DE00289A IN 2012DE00289 A IN2012DE00289 A IN 2012DE00289A IN 289DE2012 A IN289DE2012 A IN 289DE2012A IN 2012DE00289 A IN2012DE00289 A IN 2012DE00289A
- Authority
- IN
- India
- Prior art keywords
- ivabradine
- synthesis
- formula
- pharmaceutically acceptable
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
- C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D233/16—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1100446A FR2971507B1 (fr) | 2011-02-14 | 2011-02-14 | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DE00289A true IN2012DE00289A (ru) | 2015-04-10 |
Family
ID=43901397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN289DE2012 IN2012DE00289A (ru) | 2011-02-14 | 2012-02-02 |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US8476426B2 (ru) |
| EP (1) | EP2487158B1 (ru) |
| JP (1) | JP5475813B2 (ru) |
| KR (1) | KR101372389B1 (ru) |
| CN (1) | CN102633720B (ru) |
| AR (1) | AR085344A1 (ru) |
| AU (1) | AU2012200439B2 (ru) |
| BR (1) | BR102012003254A2 (ru) |
| CA (1) | CA2767893C (ru) |
| CL (1) | CL2012000270A1 (ru) |
| CY (1) | CY1113983T1 (ru) |
| DK (1) | DK2487158T3 (ru) |
| EA (1) | EA020735B1 (ru) |
| ES (1) | ES2408213T3 (ru) |
| FR (1) | FR2971507B1 (ru) |
| GE (1) | GEP20135970B (ru) |
| HR (1) | HRP20130368T1 (ru) |
| IN (1) | IN2012DE00289A (ru) |
| JO (1) | JO2930B1 (ru) |
| MA (1) | MA34990B1 (ru) |
| ME (1) | ME01479B (ru) |
| MX (1) | MX337997B (ru) |
| MY (1) | MY171954A (ru) |
| NZ (1) | NZ598138A (ru) |
| PE (1) | PE20121741A1 (ru) |
| PL (1) | PL2487158T3 (ru) |
| PT (1) | PT2487158E (ru) |
| RS (1) | RS52699B (ru) |
| SA (1) | SA112330272B1 (ru) |
| SG (1) | SG183607A1 (ru) |
| SI (1) | SI2487158T1 (ru) |
| TW (1) | TWI430993B (ru) |
| UA (1) | UA110326C2 (ru) |
| UY (1) | UY33893A (ru) |
| WO (1) | WO2012110716A1 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102827019B (zh) * | 2012-09-12 | 2014-12-10 | 江苏宇田生物医药科技有限公司 | 一组新的苯并环丁烷化合物及其在化学合成中的应用 |
| CN103848789B (zh) * | 2012-11-29 | 2016-05-18 | 江苏恒瑞医药股份有限公司 | 一种伊伐布雷定的制备方法 |
| CN104447553B (zh) * | 2013-09-22 | 2017-02-01 | 广东众生药业股份有限公司 | 伊伐布雷定及其中间体的制备方法 |
| CN104829470B (zh) * | 2015-04-20 | 2017-08-25 | 江苏宇田医药有限公司 | 一组合成伊伐布雷定的中间体化合物及其应用 |
| KR200488336Y1 (ko) | 2017-01-04 | 2019-01-15 | 한전케이피에스 주식회사 | 저압터빈의 구동기 커플링용 분해 조립 작업대 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US179316A (en) * | 1876-06-27 | Improvement in processes of preparing and producing colored photographs on glass | ||
| FR2681862B1 (fr) | 1991-09-27 | 1993-11-12 | Adir Cie | Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent. |
| FR2868775B1 (fr) * | 2004-04-13 | 2008-04-11 | Servier Lab | Nouveau procede de synthese de derives de la 1,3,4,5- tetrahydro-2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| FR2868777B1 (fr) * | 2004-04-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| WO2008065681A2 (en) * | 2006-11-30 | 2008-06-05 | Cadila Healthcare Limited | Process for preparation of ivabradine hydrochloride |
| KR101478855B1 (ko) * | 2007-05-30 | 2015-01-02 | 인드-스위프트 래버러토리즈 리미티드 | 이바브라딘 히드로클로라이드 및 그의 다형태의 제조방법 |
| FR2933975B1 (fr) * | 2008-07-17 | 2011-02-18 | Servier Lab | Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
| CN101723897B (zh) * | 2008-10-31 | 2011-11-16 | 齐鲁制药有限公司 | 伊伐布雷定的合成方法 |
| WO2010072409A1 (en) * | 2008-12-22 | 2010-07-01 | Krka, D. D., Novo Mesto | Process for preparation of ivabradine |
| FR2940287B1 (fr) * | 2008-12-24 | 2010-12-24 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
| FR2941695B1 (fr) * | 2009-02-04 | 2011-02-18 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| ME00986B (me) * | 2009-03-31 | 2012-06-20 | Servier Lab | Novi postupak sinteze ivabradina i njegovih adicionih soli sa farmaceutski prihvatljivom kiselinom |
-
2011
- 2011-02-14 FR FR1100446A patent/FR2971507B1/fr not_active Expired - Fee Related
-
2012
- 2012-01-24 PE PE2012000091A patent/PE20121741A1/es active IP Right Grant
- 2012-01-25 AU AU2012200439A patent/AU2012200439B2/en not_active Ceased
- 2012-01-27 SG SG2012005856A patent/SG183607A1/en unknown
- 2012-01-29 JO JO201221A patent/JO2930B1/en active
- 2012-01-31 MY MYPI2012700016A patent/MY171954A/en unknown
- 2012-02-01 CL CL2012000270A patent/CL2012000270A1/es unknown
- 2012-02-02 IN IN289DE2012 patent/IN2012DE00289A/en unknown
- 2012-02-03 UY UY0001033893A patent/UY33893A/es unknown
- 2012-02-06 CA CA2767893A patent/CA2767893C/fr not_active Expired - Fee Related
- 2012-02-09 MX MX2012001722A patent/MX337997B/es active IP Right Grant
- 2012-02-09 NZ NZ598138A patent/NZ598138A/xx not_active IP Right Cessation
- 2012-02-09 US US13/369,690 patent/US8476426B2/en not_active Expired - Fee Related
- 2012-02-09 AR ARP120100424A patent/AR085344A1/es unknown
- 2012-02-10 GE GEAP201212569A patent/GEP20135970B/en unknown
- 2012-02-10 EA EA201200123A patent/EA020735B1/ru not_active IP Right Cessation
- 2012-02-13 SA SA112330272A patent/SA112330272B1/ar unknown
- 2012-02-13 RS RS20130095A patent/RS52699B/en unknown
- 2012-02-13 JP JP2012028129A patent/JP5475813B2/ja active Active
- 2012-02-13 CN CN201210031500.2A patent/CN102633720B/zh not_active Expired - Fee Related
- 2012-02-13 ES ES12290050T patent/ES2408213T3/es active Active
- 2012-02-13 ME MEP-2013-41A patent/ME01479B/me unknown
- 2012-02-13 DK DK12290050.9T patent/DK2487158T3/da active
- 2012-02-13 PL PL12290050T patent/PL2487158T3/pl unknown
- 2012-02-13 WO PCT/FR2012/000055 patent/WO2012110716A1/fr active Application Filing
- 2012-02-13 EP EP12290050A patent/EP2487158B1/fr active Active
- 2012-02-13 SI SI201230001T patent/SI2487158T1/sl unknown
- 2012-02-13 BR BRBR102012003254-6A patent/BR102012003254A2/pt not_active Application Discontinuation
- 2012-02-13 PT PT122900509T patent/PT2487158E/pt unknown
- 2012-02-13 TW TW101104569A patent/TWI430993B/zh not_active IP Right Cessation
- 2012-02-13 UA UAA201201495A patent/UA110326C2/uk unknown
- 2012-02-14 KR KR1020120015001A patent/KR101372389B1/ko active IP Right Grant
- 2012-02-14 MA MA34630A patent/MA34990B1/fr unknown
-
2013
- 2013-04-26 HR HRP20130368AT patent/HRP20130368T1/hr unknown
- 2013-05-08 CY CY20131100371T patent/CY1113983T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JO2807B1 (en) | A new process for the synthesis of ivabradine and its addition salts with pharmaceutically acceptable acid. | |
| MY156630A (en) | New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | |
| MY150014A (en) | New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | |
| MY169295A (en) | New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | |
| IN2012DE00289A (ru) | ||
| MY145611A (en) | New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | |
| JO2854B1 (en) | A new method for the synthesis of anfabradine and its added salts with acid is pharmaceutically acceptable. | |
| MY170662A (en) | New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | |
| IN2014DE01203A (ru) | ||
| MY159691A (en) | New process for the synthesis of 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | |
| JO3086B1 (ar) | طريقة جديدة لتصنيع الإيفابرادين وأملاح مضافة منه مع حمض مقبول دوائياً | |
| JO3083B1 (ar) | عملية جديدة لتخليق إيفابرادين وأملاحه المضافة مع حمض مقبول صيدلانيا | |
| SA113340924B1 (ar) | عملية جديدة لتخليق 3- (2- برومو- 4،5 - داي ميثوكسي فينيل)بروبان نيتريل، وتطبيقها في تخليق إيڤابرادين وأملاح الإضافة منه مع حمض مقبول صيدلانياً | |
| SG165255A1 (en) | New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid |