IN187721B - - Google Patents

Info

Publication number
IN187721B
IN187721B IN1479MA1998A IN187721B IN 187721 B IN187721 B IN 187721B IN 1479MA1998 A IN1479MA1998 A IN 1479MA1998A IN 187721 B IN187721 B IN 187721B
Authority
IN
India
Prior art keywords
insulin
pro
recombinant human
isolated
vector
Prior art date
Application number
Other languages
English (en)
Inventor
Astolf Filho Spartaco
De Lima Beatriz Dolabela
Josef Ernst Thiemann
De Heloisa Ribeiro Tunes Sousa
Luciano Vilela
Original Assignee
Univ Brasilia
Biobras S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brasilia, Biobras S A filed Critical Univ Brasilia
Publication of IN187721B publication Critical patent/IN187721B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN1479MA1998 1997-07-02 1998-07-02 IN187721B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/886,967 US6068993A (en) 1997-07-02 1997-07-02 Vector for expression of heterologous protein and methods for extracting recombinant protein and for purifying isolated recombinant insulin

Publications (1)

Publication Number Publication Date
IN187721B true IN187721B (enExample) 2002-06-15

Family

ID=25390172

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1479MA1998 IN187721B (enExample) 1997-07-02 1998-07-02

Country Status (11)

Country Link
US (4) US6068993A (enExample)
EP (1) EP0996713B1 (enExample)
AT (1) ATE278776T1 (enExample)
BR (1) BR9810650B1 (enExample)
CA (2) CA2294760C (enExample)
DE (1) DE69826864T2 (enExample)
IL (2) IL133832A0 (enExample)
IN (1) IN187721B (enExample)
PL (1) PL194141B1 (enExample)
RU (1) RU2222598C2 (enExample)
WO (1) WO1999001548A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
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US7049286B2 (en) * 2001-08-30 2006-05-23 Diatos, S.A. Insulin conjugates and methods of use thereof
EP1558748A4 (en) * 2002-11-01 2008-10-22 Promega Corp CELL SYSE COMPOSITIONS, USE METHOD, DEVICE AND KIT
KR20070087197A (ko) 2003-09-26 2007-08-27 니뽄 다바코 산교 가부시키가이샤 잔여 리포프로테인 생산 저해 방법
RU2263147C1 (ru) * 2004-02-16 2005-10-27 Открытое акционерное общество "Национальные биотехнологии" РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pHINS05, КОДИРУЮЩАЯ ГИБРИДНЫЙ ПОЛИПЕПТИД, СОДЕРЖАЩИЙ ПРОИНСУЛИН ЧЕЛОВЕКА, КЛЕТКА ESCHERICHIA COLI, ТРАНСФОРМИРОВАННАЯ РЕКОМБИНАНТНОЙ ПЛАЗМИДНОЙ ДНК pHINS05, И ШТАММ БАКТЕРИЙ ESCHERICHIA COLI JM109/pHINS05 - ПРОДУЦЕНТ ГИБРИДНОГО ПОЛИПЕПТИДА, СОДЕРЖАЩЕГО ПРОИНСУЛИН ЧЕЛОВЕКА
US7674621B2 (en) 2004-05-21 2010-03-09 The United States Of America As Represented By The Department Of Health And Human Services Plasmids and phages for homologous recombination and methods of use
CN101027318B (zh) 2004-07-19 2016-05-25 比奥孔有限公司 胰岛素-低聚物共轭物，制剂及其用途
US7935788B2 (en) * 2004-10-04 2011-05-03 National Research Council Of Canada Reverse cumate repressor mutant
CA2580515C (en) * 2004-10-04 2017-05-02 National Research Council Of Canada Expression system, components thereof and methods of use
WO2009032664A2 (en) * 2007-08-31 2009-03-12 The Regents Of The University Of Michigan Methods and compositions for increasing biological molecule stability
US9241908B2 (en) 2007-10-16 2016-01-26 Biocon Limited Orally administrable solid pharmaceutical composition and a process thereof
JP6081908B2 (ja) * 2010-03-31 2017-02-15 アーエムシルク ゲーエムベーハー 不溶性の標的タンパク質の分離
RU2497118C1 (ru) * 2012-03-06 2013-10-27 Федеральное государственное бюджетное учреждение науки Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина Российской академии наук (ИБФМ РАН) БЫСТРЫЙ СПОСОБ ОБРАБОТКИ ГЛАДКОМЫШЕЧНЫХ КЛЕТОК КИШЕЧНИКА ГЕМОЛИЗИНОМ II Bacillus cereus
CN102617703A (zh) * 2012-04-14 2012-08-01 拜明(苏州)生物技术有限公司 一种无需裂解高效提取发酵细菌中外源表达蛋白的方法
WO2015176067A2 (en) 2014-05-16 2015-11-19 The Regents Of The University Of California A long non-coding rna expressed in aggressive cancer
WO2017040363A1 (en) 2015-09-02 2017-03-09 Merck Sharp & Dohme Corp. A process for obtaining insulin with correctly formed disulfide bonds
CN121266374B (zh) * 2025-11-25 2026-08-04 沃顿科技股份有限公司 抗污染复合纳滤膜及其制备方法

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Also Published As

Publication number Publication date
RU2222598C2 (ru) 2004-01-27
IL133832A (en) 2007-07-04
PL348669A1 (en) 2002-06-03
PL194141B1 (pl) 2007-04-30
US6509452B1 (en) 2003-01-21
CA2687542C (en) 2013-04-30
US6068993A (en) 2000-05-30
WO1999001548A2 (en) 1999-01-14
BR9810650B1 (pt) 2010-12-14
DE69826864D1 (de) 2004-11-11
DE69826864T2 (de) 2005-11-03
CA2687542A1 (en) 1999-01-14
WO1999001548A3 (en) 1999-09-10
CA2294760C (en) 2010-02-23
EP0996713B1 (en) 2004-10-06
EP0996713A1 (en) 2000-05-03
BR9810650A (pt) 2002-07-23
US20030082742A1 (en) 2003-05-01
IL133832A0 (en) 2001-04-30
CA2294760A1 (en) 1999-01-14
ATE278776T1 (de) 2004-10-15
US6699692B2 (en) 2004-03-02
US6281329B1 (en) 2001-08-28

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