IN181859B - - Google Patents

Info

Publication number
IN181859B
IN181859B IN946MA1996A IN181859B IN 181859 B IN181859 B IN 181859B IN 946MA1996 A IN946MA1996 A IN 946MA1996A IN 181859 B IN181859 B IN 181859B
Authority
IN
India
Prior art keywords
protein solution
treatment
protein
clarification
purification
Prior art date
Application number
Other languages
English (en)
Inventor
Terben Kjaersgaard Nielsen
Mads Aage Laustsen
Niels-Viktor Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IN181859B publication Critical patent/IN181859B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IN946MA1996 1995-06-02 1996-06-03 IN181859B (pm)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK62695 1995-06-02

Publications (1)

Publication Number Publication Date
IN181859B true IN181859B (pm) 1998-10-03

Family

ID=8095720

Family Applications (1)

Application Number Title Priority Date Filing Date
IN946MA1996 IN181859B (pm) 1995-06-02 1996-06-03

Country Status (9)

Country Link
EP (1) EP0828753B1 (pm)
JP (1) JPH11511118A (pm)
CN (1) CN1114613C (pm)
AT (1) ATE235506T1 (pm)
AU (1) AU5996996A (pm)
DE (1) DE69626976T2 (pm)
DK (1) DK0828753T3 (pm)
IN (1) IN181859B (pm)
WO (1) WO1996038469A1 (pm)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2810667B1 (fr) * 2000-06-23 2004-09-03 Warner Lambert Co Procede d'isolement et de purification d'une proteine, et proteine obtenue
US7659102B2 (en) 2001-02-21 2010-02-09 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
EP2333098B1 (en) 2001-02-21 2016-08-24 BASF Enzymes LLC Enzymes having alpha amylase activity and methods of use thereof
WO2002092802A1 (en) * 2001-05-14 2002-11-21 Diversa Corporation Novel methods of enzyme purification
JP5562510B2 (ja) 2001-06-28 2014-07-30 ノヴォ ノルディスク アー/エス 修飾glp−1の安定な処方剤
US7118891B2 (en) 2001-12-11 2006-10-10 Novozymes A/S Crystal harvest from fermentation broth
WO2003050274A2 (en) * 2001-12-11 2003-06-19 Novozymes A/S Process for harvesting crystalline particles from fermentation broth
CA2515340C (en) 2003-03-06 2016-04-26 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
ATE541582T1 (de) 2003-06-03 2012-02-15 Novo Nordisk As Stabilisierte pharmazeutische glp-1 peptid zusammensetzungen
EP1633391B1 (en) 2003-06-03 2011-10-19 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
BRPI0416743A (pt) 2003-11-20 2007-01-16 Novo Nordisk As formulação farmacêutica, e, métodos de preparar uma formulação de peptìdeo apropriada para uso em um dispositivo de injeção, para reduzir depósitos em equipamento de produção e no produto final, e para reduzir o entupimento de dispositivos de injeção por uma formulação de peptìdeo
WO2006024631A2 (en) 2004-08-31 2006-03-09 Novo Nordisk A/S Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
EP1817048B2 (en) 2004-11-12 2025-06-18 Novo Nordisk A/S Stable formulations of insulinoptropic peptides
ES2704040T3 (es) 2005-09-15 2019-03-13 Wyeth Llc Floculación de proteínas mediante el uso de sales
EP2479266B1 (en) 2006-12-21 2016-03-09 BASF Enzymes LLC Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
US20120252066A1 (en) * 2011-03-29 2012-10-04 Heng Meng H Methods of foam control
WO2014068083A1 (en) 2012-11-01 2014-05-08 Novozymes A/S Method for removal of dna
WO2015075302A1 (en) 2013-11-19 2015-05-28 Kemira Oyj Method for reducing colour of a biotechnological liquid
HRP20240485T1 (hr) 2017-08-24 2024-07-05 Novo Nordisk A/S Pripravci glp-1 i njihova upotreba
CN108949703A (zh) * 2018-06-28 2018-12-07 大连理工大学 一种半纤维小体类似物粗提纯方法
EP3983425A1 (en) 2019-06-13 2022-04-20 Basf Se Method of recovering a protein from fermentation broth using a divalent cation
JP2023512910A (ja) 2020-02-18 2023-03-30 ノヴォ ノルディスク アー/エス 医薬製剤
EP4217366A1 (en) 2020-09-22 2023-08-02 Basf Se Method for recovering a protein from a fermentation broth comprising a high degree of lysed cells
CN112500471B (zh) * 2020-12-22 2022-09-27 中美华世通生物医药科技(武汉)股份有限公司 一种制备高澄清度蛋白琥珀酸铁的方法
EP4565710A1 (en) 2022-08-02 2025-06-11 Basf Se Stabilized protein production process using bacillus host cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795586A (en) * 1969-08-11 1974-03-05 Pabst Brewing Co Recovery of enzymes
HU203367B (en) * 1987-01-30 1991-07-29 Int Minerals & Chem Corp Process for obtaining somatotpropins from weak aqueous solution
US4894444A (en) * 1987-07-16 1990-01-16 Merck & Co., Inc. Recovery and purification of immunogens from immunogen-alum complexes
DE3915277A1 (de) * 1989-05-10 1990-11-15 Henkel Kgaa Verfahren zur reinigung von enzymfluessigkonzentraten
DE4037530A1 (de) * 1990-11-26 1992-05-27 Henkel Kgaa Faellungsverfahren fuer exocellulaere proteine
DK91092D0 (pm) * 1992-07-10 1992-07-10 Novo Nordisk As

Also Published As

Publication number Publication date
AU5996996A (en) 1996-12-18
WO1996038469A1 (en) 1996-12-05
DK0828753T3 (da) 2003-06-30
DE69626976D1 (de) 2003-04-30
ATE235506T1 (de) 2003-04-15
CN1114613C (zh) 2003-07-16
CN1186498A (zh) 1998-07-01
JPH11511118A (ja) 1999-09-28
DE69626976T2 (de) 2004-03-04
EP0828753A1 (en) 1998-03-18
EP0828753B1 (en) 2003-03-26

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