IN164615B - - Google Patents
Info
- Publication number
- IN164615B IN164615B IN652/CAL/85A IN652CA1985A IN164615B IN 164615 B IN164615 B IN 164615B IN 652CA1985 A IN652CA1985 A IN 652CA1985A IN 164615 B IN164615 B IN 164615B
- Authority
- IN
- India
- Prior art keywords
- substituents
- chem
- compounds
- pharmaceutically acceptable
- acceptable salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/649,797 US4746676A (en) | 1984-09-12 | 1984-09-12 | Carboxyalkyl dipeptide compounds |
| US06/752,695 US4749698A (en) | 1985-07-08 | 1985-07-08 | Antihypertensive derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN164615B true IN164615B (xx) | 1989-04-22 |
Family
ID=27095707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN652/CAL/85A IN164615B (xx) | 1984-09-12 | 1985-09-16 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0175266B1 (xx) |
| KR (1) | KR860002464A (xx) |
| AT (1) | ATE135711T1 (xx) |
| AU (1) | AU578489B2 (xx) |
| CA (1) | CA1288893C (xx) |
| DE (1) | DE3588094T2 (xx) |
| DK (1) | DK412985A (xx) |
| ES (1) | ES8609364A1 (xx) |
| FI (1) | FI89716C (xx) |
| IL (1) | IL76345A (xx) |
| IN (1) | IN164615B (xx) |
| NO (1) | NO169442C (xx) |
| NZ (1) | NZ213432A (xx) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629345A (en) * | 1993-07-23 | 1997-05-13 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| US5965620A (en) * | 1993-07-23 | 1999-10-12 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
| EP0765341A4 (en) * | 1994-06-16 | 1998-09-16 | Smithkline Beecham Corp | CYCLISATION DIRECTED BY MATRIX |
| JP4898044B2 (ja) † | 1999-10-14 | 2012-03-14 | キュリス，インコーポレイテッド | ヘッジホッグシグナル伝達経路のメディエーター、それらと関連する組成物及び利用 |
| DE50015940D1 (de) | 2000-09-21 | 2010-07-29 | Abb Schweiz Ag | Konfiguration eines Leitsystems einer elektrischen Schaltanlage |
| KR101397915B1 (ko) * | 2005-12-23 | 2014-05-26 | 와이어쓰 엘엘씨 | 개질된 리신 모방 화합물 |
| DK2468724T3 (en) | 2006-12-21 | 2016-02-22 | Zealand Pharma As | Synthesis of pyrrolidine compounds |
| JP6989864B2 (ja) | 2017-05-05 | 2022-02-03 | ジーランド ファーマ，アー／エス | ギャップ結合細胞間コミュニケーションモジュレータ及び糖尿病性眼疾患の治療のためのそれらの使用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5683483A (en) * | 1979-12-13 | 1981-07-08 | Santen Pharmaceut Co Ltd | Thiazolidine compound |
| US4350704A (en) * | 1980-10-06 | 1982-09-21 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids |
| GR75019B (xx) * | 1980-09-17 | 1984-07-12 | Univ Miami | |
| US4462943A (en) * | 1980-11-24 | 1984-07-31 | E. R. Squibb & Sons, Inc. | Carboxyalkyl amino acid derivatives of various substituted prolines |
| FR2501399B1 (fr) * | 1981-03-03 | 1987-06-19 | France Etat | Dispositif d'affichage de messages graphiques transmis par des systemes de videotex |
| EP0080822A1 (en) * | 1981-11-27 | 1983-06-08 | Beecham Group Plc | Anti-hypertensive prolinol-based peptides |
| DE3360065D1 (en) * | 1982-03-08 | 1985-03-28 | Schering Corp | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them |
| ZA832762B (en) * | 1982-04-30 | 1983-12-28 | Squibb & Sons Inc | Substituted 4-phenoxy prolines |
| IL69136A0 (en) * | 1982-07-19 | 1983-10-31 | Squibb & Sons Inc | Substituted peptide compounds |
| US4623729A (en) * | 1982-07-22 | 1986-11-18 | E. R. Squibb & Sons, Inc. | Acylalkylaminocarbonyl substituted amino and imino acid compounds |
| US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
| DK156484A (da) * | 1983-03-16 | 1984-09-17 | Usv Pharma Corp | Aminosyrederivater |
| ZA843899B (en) * | 1983-05-23 | 1984-12-24 | Usv Pharma Corp | Compounds for treating hypertension |
-
1985
- 1985-09-10 AU AU47331/85A patent/AU578489B2/en not_active Ceased
- 1985-09-10 DE DE3588094T patent/DE3588094T2/de not_active Expired - Fee Related
- 1985-09-10 EP EP85111454A patent/EP0175266B1/en not_active Expired - Lifetime
- 1985-09-10 AT AT85111454T patent/ATE135711T1/de not_active IP Right Cessation
- 1985-09-10 IL IL76345A patent/IL76345A/xx unknown
- 1985-09-11 DK DK412985A patent/DK412985A/da not_active Application Discontinuation
- 1985-09-11 NO NO853551A patent/NO169442C/no unknown
- 1985-09-11 KR KR1019850006633A patent/KR860002464A/ko not_active Application Discontinuation
- 1985-09-11 ES ES546866A patent/ES8609364A1/es not_active Expired
- 1985-09-11 NZ NZ213432A patent/NZ213432A/xx unknown
- 1985-09-11 CA CA000490437A patent/CA1288893C/en not_active Expired - Lifetime
- 1985-09-12 FI FI853494A patent/FI89716C/fi not_active IP Right Cessation
- 1985-09-16 IN IN652/CAL/85A patent/IN164615B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3588094T2 (de) | 1996-08-22 |
| CA1288893C (en) | 1991-09-10 |
| ES546866A0 (es) | 1986-07-16 |
| AU578489B2 (en) | 1988-10-27 |
| EP0175266A3 (en) | 1988-08-03 |
| ATE135711T1 (de) | 1996-04-15 |
| EP0175266B1 (en) | 1996-03-20 |
| IL76345A0 (en) | 1986-01-31 |
| EP0175266A2 (en) | 1986-03-26 |
| FI853494A0 (fi) | 1985-09-12 |
| DK412985D0 (da) | 1985-09-11 |
| DK412985A (da) | 1986-03-13 |
| NO853551L (no) | 1986-03-13 |
| AU4733185A (en) | 1986-03-20 |
| NZ213432A (en) | 1988-11-29 |
| NO169442B (no) | 1992-03-16 |
| NO169442C (no) | 1992-06-24 |
| IL76345A (en) | 1988-12-30 |
| FI89716C (fi) | 1993-11-10 |
| ES8609364A1 (es) | 1986-07-16 |
| DE3588094D1 (de) | 1996-04-25 |
| FI89716B (fi) | 1993-07-30 |
| FI853494L (fi) | 1986-03-13 |
| KR860002464A (ko) | 1986-04-26 |
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