IL99902A0 - Indane and quinoline derivatives and pharmaceutical compositions containing the same - Google Patents
Indane and quinoline derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL99902A0 IL99902A0 IL99902A IL9990291A IL99902A0 IL 99902 A0 IL99902 A0 IL 99902A0 IL 99902 A IL99902 A IL 99902A IL 9990291 A IL9990291 A IL 9990291A IL 99902 A0 IL99902 A0 IL 99902A0
- Authority
- IL
- Israel
- Prior art keywords
- indane
- same
- pharmaceutical compositions
- compositions containing
- quinoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61835790A | 1990-11-26 | 1990-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL99902A0 true IL99902A0 (en) | 1992-08-18 |
Family
ID=24477368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL99902A IL99902A0 (en) | 1990-11-26 | 1991-10-30 | Indane and quinoline derivatives and pharmaceutical compositions containing the same |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5401848A (pl) |
| EP (1) | EP0488616A1 (pl) |
| JP (1) | JPH04352753A (pl) |
| KR (1) | KR920009783A (pl) |
| CN (1) | CN1061961A (pl) |
| AU (1) | AU637535B2 (pl) |
| CA (1) | CA2054637A1 (pl) |
| FI (1) | FI915530A7 (pl) |
| HU (1) | HU209470B (pl) |
| IE (1) | IE913867A1 (pl) |
| IL (1) | IL99902A0 (pl) |
| NO (1) | NO176095C (pl) |
| NZ (1) | NZ240615A (pl) |
| PL (1) | PL166983B1 (pl) |
| PT (1) | PT99605A (pl) |
| RU (1) | RU2058980C1 (pl) |
| ZA (1) | ZA918539B (pl) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU651105B2 (en) * | 1990-06-18 | 1994-07-14 | E.R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
| US5453421A (en) * | 1992-09-11 | 1995-09-26 | E. R. Squibb & Sons, Inc. | Aryl and heterocyclic substituted propenamide derivatives |
| US5374643A (en) * | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
| US5514690A (en) * | 1992-11-17 | 1996-05-07 | E. R. Squibb & Sons, Inc. | Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline |
| GB9225860D0 (en) * | 1992-12-11 | 1993-02-03 | Smithkline Beecham Plc | Novel treatment |
| GB9225859D0 (en) * | 1992-12-11 | 1993-02-03 | Smithkline Beecham Plc | Novel treatment |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| WO1995033726A1 (en) * | 1994-06-09 | 1995-12-14 | Ss Pharmaceutical Co., Ltd. | 4-quinolinone derivative or salt thereof |
| US5612370A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phenylglycine and phenylalaninen amido benzopyran derivatives |
| US5612323A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phosphinic ester substituted benzopyran derivatives |
| US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
| US5629429A (en) * | 1995-06-07 | 1997-05-13 | Bristol-Myers Squibb Company | Process for preparing 4-arylamino-benzopyran and related compounds |
| WO1997026300A1 (en) * | 1996-01-22 | 1997-07-24 | Eli Lilly And Company | Combinatorial process for preparing substituted indane libraries |
| US6083986A (en) * | 1996-07-26 | 2000-07-04 | Icagen, Inc. | Potassium channel inhibitors |
| US6333337B1 (en) | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
| AU4997199A (en) * | 1998-07-16 | 2000-02-07 | Axys Pharmaceuticals, Inc. | Process for the synthesis of benzopyran derivatives |
| GT199900147A (es) | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
| US6147090A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
| US6140342A (en) * | 1998-09-17 | 2000-10-31 | Pfizer Inc. | Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines |
| US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| WO2001046155A1 (en) * | 1999-12-21 | 2001-06-28 | Icagen, Inc. | Potassium channel inhibitors |
| US6566380B2 (en) * | 2000-07-25 | 2003-05-20 | Icagen, Inc. | Potassium channel inhibitors |
| US6620849B2 (en) | 2000-07-26 | 2003-09-16 | Icafen, Inc. | Potassium channel inhibitors |
| US6849634B2 (en) | 2000-12-21 | 2005-02-01 | Icagen | Potassium channel inhibitors |
| BRPI0510642A (pt) | 2004-05-05 | 2007-11-20 | Hoffmann La Roche | arilsulfonil benzodioxanos úteis para modulação do receptor de 5-ht6, do receptor de 5ht2a ou ambos |
| ES2314749T3 (es) | 2004-12-21 | 2009-03-16 | F. Hoffmann-La Roche Ag | Derivados de tetralina y de indano y usos de los mismos como antagonistas de 5-ht. |
| JP4738418B2 (ja) | 2004-12-21 | 2011-08-03 | エフ．ホフマン−ラ ロシュ アーゲー | クロマン誘導体及びｃｎｓ障害の処置におけるその使用 |
| ATE455755T1 (de) | 2004-12-21 | 2010-02-15 | Hoffmann La Roche | Tetralin- und indanderivate und deren anwendungen |
| RU2396264C2 (ru) | 2004-12-21 | 2010-08-10 | Ф. Хоффманн-Ля Рош Аг | Производные хромана и их применение в качестве лигандов 5-нт рецептора |
| MX2007007481A (es) | 2004-12-21 | 2007-07-20 | Hoffmann La Roche | Derivados de tetralina e indano y usos de los mismos. |
| CN100381398C (zh) * | 2005-07-29 | 2008-04-16 | 南京理工大学 | AlN－Si3N4－SiC陶瓷材料的制备方法 |
| ES2359735T3 (es) | 2005-11-03 | 2011-05-26 | F. Hoffmann-La Roche Ag | Arilsulfonilcromanos como inhibidores de 5-ht6. |
| WO2007147763A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
| EP2035370A2 (en) | 2006-06-20 | 2009-03-18 | F. Hoffmann-Roche AG | Tetralin and indane derivatives and uses thereof |
| KR101064001B1 (ko) | 2006-06-20 | 2011-09-08 | 에프. 호프만-라 로슈 아게 | 아릴설폰아미딜 테트랄린 유도체 및 이의 용도 |
| CN107540566A (zh) * | 2017-08-28 | 2018-01-05 | 江苏绿叶农化有限公司 | 一种炔苯酰草胺的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3486354T2 (de) * | 1983-05-18 | 1995-03-30 | Beecham Group Plc | Chroman- und Chromenderivate. |
| GB8414987D0 (en) * | 1984-06-12 | 1984-07-18 | Beecham Group Plc | Active compounds |
| DE3579390D1 (de) * | 1984-06-22 | 1990-10-04 | Beecham Group Plc | Wirksame benzopyranverbindungen. |
| DE3583780D1 (de) * | 1984-08-31 | 1991-09-19 | Otsuka Pharma Co Ltd | 2,3-dihydro-1h-inden-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
| AU609232B2 (en) * | 1987-12-14 | 1991-04-26 | Beecham Group Plc | Novel indane derivatives possessing smooth muscle relaxant activity |
| GB8730052D0 (en) * | 1987-12-23 | 1988-02-03 | Beecham Group Plc | Novel compounds |
| US4988723A (en) * | 1988-06-02 | 1991-01-29 | Fujisawa Pharmaceutical Co., Ltd. | Benzopyran derivatives and their use as anti-hypertensives |
| ATE139775T1 (de) * | 1988-09-16 | 1996-07-15 | Beecham Group Plc | Benzopyranderivate mit einer blutdrucksenkenden wirkung |
| EP0386839B1 (en) * | 1989-03-08 | 1997-01-15 | Merck Sharp & Dohme Ltd. | Tetrahydroquinoline derivatives useful for neurodegenerative disorders |
| AU632809B2 (en) * | 1989-05-25 | 1993-01-14 | Takeda Chemical Industries Ltd. | Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof |
| US5140031A (en) * | 1989-05-31 | 1992-08-18 | E. R. Squibb & Sons, Inc. | Pyranyl cyanoguanidine derivatives |
-
1991
- 1991-10-15 US US07/776,921 patent/US5401848A/en not_active Expired - Fee Related
- 1991-10-25 ZA ZA918539A patent/ZA918539B/xx unknown
- 1991-10-30 IL IL99902A patent/IL99902A0/xx unknown
- 1991-10-31 CA CA002054637A patent/CA2054637A1/en not_active Abandoned
- 1991-11-06 IE IE386791A patent/IE913867A1/en not_active Application Discontinuation
- 1991-11-15 NZ NZ240615A patent/NZ240615A/en unknown
- 1991-11-21 JP JP3306038A patent/JPH04352753A/ja not_active Withdrawn
- 1991-11-21 AU AU88040/91A patent/AU637535B2/en not_active Ceased
- 1991-11-25 RU SU915010280A patent/RU2058980C1/ru active
- 1991-11-25 EP EP91310811A patent/EP0488616A1/en not_active Ceased
- 1991-11-25 FI FI915530A patent/FI915530A7/fi not_active Application Discontinuation
- 1991-11-25 KR KR1019910021074A patent/KR920009783A/ko not_active Withdrawn
- 1991-11-25 HU HU913664A patent/HU209470B/hu not_active IP Right Cessation
- 1991-11-25 NO NO914602A patent/NO176095C/no unknown
- 1991-11-26 PL PL91292536A patent/PL166983B1/pl unknown
- 1991-11-26 CN CN91111172A patent/CN1061961A/zh active Pending
- 1991-11-26 PT PT99605A patent/PT99605A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUT60467A (en) | 1992-09-28 |
| RU2058980C1 (ru) | 1996-04-27 |
| FI915530A0 (fi) | 1991-11-25 |
| PL166983B1 (pl) | 1995-07-31 |
| NZ240615A (en) | 1994-05-26 |
| EP0488616A1 (en) | 1992-06-03 |
| KR920009783A (ko) | 1992-06-25 |
| NO914602L (no) | 1992-05-27 |
| IE913867A1 (en) | 1992-06-03 |
| JPH04352753A (ja) | 1992-12-07 |
| NO914602D0 (no) | 1991-11-25 |
| HU913664D0 (en) | 1992-02-28 |
| FI915530A7 (fi) | 1992-05-27 |
| PT99605A (pt) | 1992-10-30 |
| PL292536A1 (en) | 1992-09-21 |
| HU209470B (en) | 1994-06-28 |
| CN1061961A (zh) | 1992-06-17 |
| NO176095B (no) | 1994-10-24 |
| ZA918539B (en) | 1992-08-26 |
| AU8804091A (en) | 1992-05-28 |
| NO176095C (no) | 1995-02-01 |
| US5401848A (en) | 1995-03-28 |
| CA2054637A1 (en) | 1992-05-27 |
| AU637535B2 (en) | 1993-05-27 |
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