IL99902A0 - Indane and quinoline derivatives and pharmaceutical compositions containing the same - Google Patents

Indane and quinoline derivatives and pharmaceutical compositions containing the same

Info

Publication number
IL99902A0
IL99902A0 IL99902A IL9990291A IL99902A0 IL 99902 A0 IL99902 A0 IL 99902A0 IL 99902 A IL99902 A IL 99902A IL 9990291 A IL9990291 A IL 9990291A IL 99902 A0 IL99902 A0 IL 99902A0
Authority
IL
Israel
Prior art keywords
indane
same
pharmaceutical compositions
compositions containing
quinoline derivatives
Prior art date
Application number
IL99902A
Other languages
English (en)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IL99902A0 publication Critical patent/IL99902A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
IL99902A 1990-11-26 1991-10-30 Indane and quinoline derivatives and pharmaceutical compositions containing the same IL99902A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61835790A 1990-11-26 1990-11-26

Publications (1)

Publication Number Publication Date
IL99902A0 true IL99902A0 (en) 1992-08-18

Family

ID=24477368

Family Applications (1)

Application Number Title Priority Date Filing Date
IL99902A IL99902A0 (en) 1990-11-26 1991-10-30 Indane and quinoline derivatives and pharmaceutical compositions containing the same

Country Status (17)

Country Link
US (1) US5401848A (pl)
EP (1) EP0488616A1 (pl)
JP (1) JPH04352753A (pl)
KR (1) KR920009783A (pl)
CN (1) CN1061961A (pl)
AU (1) AU637535B2 (pl)
CA (1) CA2054637A1 (pl)
FI (1) FI915530A7 (pl)
HU (1) HU209470B (pl)
IE (1) IE913867A1 (pl)
IL (1) IL99902A0 (pl)
NO (1) NO176095C (pl)
NZ (1) NZ240615A (pl)
PL (1) PL166983B1 (pl)
PT (1) PT99605A (pl)
RU (1) RU2058980C1 (pl)
ZA (1) ZA918539B (pl)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU651105B2 (en) * 1990-06-18 1994-07-14 E.R. Squibb & Sons, Inc. Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
US5374643A (en) * 1992-09-11 1994-12-20 E. R. Squibb & Sons, Inc. Aryl urea (thiourea) and cyanoguanidine derivatives
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
US5514690A (en) * 1992-11-17 1996-05-07 E. R. Squibb & Sons, Inc. Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
GB9225860D0 (en) * 1992-12-11 1993-02-03 Smithkline Beecham Plc Novel treatment
GB9225859D0 (en) * 1992-12-11 1993-02-03 Smithkline Beecham Plc Novel treatment
US5401758A (en) * 1993-10-07 1995-03-28 Bristol-Myers Squibb Company Pyridinyl cyanoguanidine compounds
KR100254106B1 (ko) * 1994-06-09 2000-05-01 타이도 나오카타 4-퀴놀리논 유도체 또는 그의 염
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
DK0874625T3 (da) * 1996-01-22 2005-06-20 Lilly Co Eli Indanderivater til antipsykotiske præparater
US6083986A (en) * 1996-07-26 2000-07-04 Icagen, Inc. Potassium channel inhibitors
US6333337B1 (en) 1998-01-27 2001-12-25 Icagen, Inc. Potassium channel inhibitors
AU4997199A (en) * 1998-07-16 2000-02-07 Axys Pharmaceuticals, Inc. Process for the synthesis of benzopyran derivatives
US6147090A (en) * 1998-09-17 2000-11-14 Pfizer Inc. 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
US6140342A (en) * 1998-09-17 2000-10-31 Pfizer Inc. Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines
US6147089A (en) * 1998-09-17 2000-11-14 Pfizer Inc. Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
GT199900147A (es) 1998-09-17 1999-09-06 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
WO2001046155A1 (en) 1999-12-21 2001-06-28 Icagen, Inc. Potassium channel inhibitors
US6566380B2 (en) 2000-07-25 2003-05-20 Icagen, Inc. Potassium channel inhibitors
US6620849B2 (en) 2000-07-26 2003-09-16 Icafen, Inc. Potassium channel inhibitors
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors
MXPA06012621A (es) 2004-05-05 2006-12-15 Hoffmann La Roche Arilsulfonil benzodioxanos utiles para la modulacion del receptor 5-ht6, el receptor 5-ht2a o ambos.
JP4738418B2 (ja) 2004-12-21 2011-08-03 エフ.ホフマン−ラ ロシュ アーゲー クロマン誘導体及びcns障害の処置におけるその使用
ES2306275T3 (es) 2004-12-21 2008-11-01 F. Hoffmann-La Roche Ag Derivados de cromano y sus usos como ligandos dde receptores 5-ht.
CA2591800A1 (en) 2004-12-21 2006-06-29 F.Hoffmann-La Roche Ag Tetralin and indane derivatives and uses thereof as 5-ht antagonists
BRPI0515835A (pt) 2004-12-21 2008-08-12 Hoffmann La Roche derivados de tetralina e de indano e seus usos
PT1831159E (pt) 2004-12-21 2010-03-03 Hoffmann La Roche Derivados de tetralina e de indano e as suas utilizações
CN100381398C (zh) * 2005-07-29 2008-04-16 南京理工大学 AlN-Si3N4-SiC陶瓷材料的制备方法
WO2007051735A1 (en) 2005-11-03 2007-05-10 F. Hoffmann-La Roche Ag Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors
WO2007147763A1 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Arylsulfonyl naphthalene derivatives and uses thereof
JP2009541248A (ja) 2006-06-20 2009-11-26 エフ.ホフマン−ラ ロシュ アーゲー アリールスルホンアミジルテトラリン誘導体及びそれらの使用
KR101066306B1 (ko) 2006-06-20 2011-09-20 에프. 호프만-라 로슈 아게 테트랄린 및 인데인 유도체 및 이들의 용도
CN107540566A (zh) * 2017-08-28 2018-01-05 江苏绿叶农化有限公司 一种炔苯酰草胺的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3486354T2 (de) * 1983-05-18 1995-03-30 Beecham Group Plc Chroman- und Chromenderivate.
GB8414987D0 (en) * 1984-06-12 1984-07-18 Beecham Group Plc Active compounds
EP0172352B1 (en) * 1984-06-22 1990-08-29 Beecham Group Plc Active benzopyran compounds
DE3583780D1 (de) * 1984-08-31 1991-09-19 Otsuka Pharma Co Ltd 2,3-dihydro-1h-inden-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DK691488A (da) * 1987-12-14 1989-06-15 Beecham Group Plc Hidtil ukendte forbindelser
GB8730052D0 (en) * 1987-12-23 1988-02-03 Beecham Group Plc Novel compounds
US4988723A (en) * 1988-06-02 1991-01-29 Fujisawa Pharmaceutical Co., Ltd. Benzopyran derivatives and their use as anti-hypertensives
DE68926729T2 (de) * 1988-09-16 1997-02-13 Beecham Group Plc Benzopyranderivate mit einer blutdrucksenkenden Wirkung
ATE147732T1 (de) * 1989-03-08 1997-02-15 Merck Sharp & Dohme Tetrahydroquinolin-derivate, verwendbar bei neurodegenerativen krankheiten
AU632809B2 (en) * 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
US5140031A (en) * 1989-05-31 1992-08-18 E. R. Squibb & Sons, Inc. Pyranyl cyanoguanidine derivatives

Also Published As

Publication number Publication date
FI915530A7 (fi) 1992-05-27
CN1061961A (zh) 1992-06-17
KR920009783A (ko) 1992-06-25
JPH04352753A (ja) 1992-12-07
FI915530A0 (fi) 1991-11-25
HUT60467A (en) 1992-09-28
HU209470B (en) 1994-06-28
EP0488616A1 (en) 1992-06-03
RU2058980C1 (ru) 1996-04-27
NZ240615A (en) 1994-05-26
PT99605A (pt) 1992-10-30
ZA918539B (en) 1992-08-26
AU8804091A (en) 1992-05-28
NO176095B (no) 1994-10-24
HU913664D0 (en) 1992-02-28
PL166983B1 (pl) 1995-07-31
US5401848A (en) 1995-03-28
NO914602L (no) 1992-05-27
PL292536A1 (en) 1992-09-21
NO914602D0 (no) 1991-11-25
AU637535B2 (en) 1993-05-27
IE913867A1 (en) 1992-06-03
CA2054637A1 (en) 1992-05-27
NO176095C (no) 1995-02-01

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