ZA918539B - Indane and quinoline derivatives - Google Patents
Indane and quinoline derivativesInfo
- Publication number
- ZA918539B ZA918539B ZA918539A ZA918539A ZA918539B ZA 918539 B ZA918539 B ZA 918539B ZA 918539 A ZA918539 A ZA 918539A ZA 918539 A ZA918539 A ZA 918539A ZA 918539 B ZA918539 B ZA 918539B
- Authority
- ZA
- South Africa
- Prior art keywords
- indane
- quinoline derivatives
- quinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61835790A | 1990-11-26 | 1990-11-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA918539B true ZA918539B (en) | 1992-08-26 |
Family
ID=24477368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA918539A ZA918539B (en) | 1990-11-26 | 1991-10-25 | Indane and quinoline derivatives |
Country Status (17)
Country | Link |
---|---|
US (1) | US5401848A (xx) |
EP (1) | EP0488616A1 (xx) |
JP (1) | JPH04352753A (xx) |
KR (1) | KR920009783A (xx) |
CN (1) | CN1061961A (xx) |
AU (1) | AU637535B2 (xx) |
CA (1) | CA2054637A1 (xx) |
FI (1) | FI915530A (xx) |
HU (1) | HU209470B (xx) |
IE (1) | IE913867A1 (xx) |
IL (1) | IL99902A0 (xx) |
NO (1) | NO176095C (xx) |
NZ (1) | NZ240615A (xx) |
PL (1) | PL166983B1 (xx) |
PT (1) | PT99605A (xx) |
RU (1) | RU2058980C1 (xx) |
ZA (1) | ZA918539B (xx) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU651105B2 (en) * | 1990-06-18 | 1994-07-14 | E.R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
US5453421A (en) * | 1992-09-11 | 1995-09-26 | E. R. Squibb & Sons, Inc. | Aryl and heterocyclic substituted propenamide derivatives |
US5374643A (en) * | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
US5514690A (en) * | 1992-11-17 | 1996-05-07 | E. R. Squibb & Sons, Inc. | Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline |
GB9225859D0 (en) * | 1992-12-11 | 1993-02-03 | Smithkline Beecham Plc | Novel treatment |
GB9225860D0 (en) * | 1992-12-11 | 1993-02-03 | Smithkline Beecham Plc | Novel treatment |
US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
US5789419A (en) * | 1994-06-09 | 1998-08-04 | Ss Pharmaceutical Co., Ltd. | 4-quinolinone derivative or salt thereof |
US5612370A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phenylglycine and phenylalaninen amido benzopyran derivatives |
US5612323A (en) * | 1995-06-07 | 1997-03-18 | Bristol-Myers Squibb Company | Phosphinic ester substituted benzopyran derivatives |
US5629429A (en) * | 1995-06-07 | 1997-05-13 | Bristol-Myers Squibb Company | Process for preparing 4-arylamino-benzopyran and related compounds |
US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
JP2001521484A (ja) * | 1996-01-22 | 2001-11-06 | イーライ・リリー・アンド・カンパニー | 置換されたインダンのライブラリーを製造するための組み合わせ方法 |
US6083986A (en) * | 1996-07-26 | 2000-07-04 | Icagen, Inc. | Potassium channel inhibitors |
US6333337B1 (en) | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
AU4997199A (en) * | 1998-07-16 | 2000-02-07 | Axys Pharmaceuticals, Inc. | Process for the synthesis of benzopyran derivatives |
US6140342A (en) * | 1998-09-17 | 2000-10-31 | Pfizer Inc. | Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines |
US6147090A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
GT199900147A (es) | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
JP2003518101A (ja) * | 1999-12-21 | 2003-06-03 | アイカゲン インコーポレイテッド | カリウムチャネル阻害剤 |
US6566380B2 (en) * | 2000-07-25 | 2003-05-20 | Icagen, Inc. | Potassium channel inhibitors |
US6620849B2 (en) | 2000-07-26 | 2003-09-16 | Icafen, Inc. | Potassium channel inhibitors |
US6849634B2 (en) | 2000-12-21 | 2005-02-01 | Icagen | Potassium channel inhibitors |
AU2005238179B2 (en) | 2004-05-05 | 2010-08-26 | F. Hoffmann-La Roche Ag | Arylsulfonyl benzodioxanes useful for modulating the 5-HT6 receptor, the 5-HT2A receptor or both |
WO2006066756A1 (en) | 2004-12-21 | 2006-06-29 | F. Hoffmann-La Roche Ag | Chroman derivatives and uses thereof in the treatment of cns disorders |
DE602005009977D1 (de) | 2004-12-21 | 2008-11-06 | Hoffmann La Roche | Tetralin- und indanderivate und deren anwendungen als 5-ht-antagonisten |
ATE455755T1 (de) | 2004-12-21 | 2010-02-15 | Hoffmann La Roche | Tetralin- und indanderivate und deren anwendungen |
BRPI0516381A (pt) | 2004-12-21 | 2008-09-02 | Hoffmann La Roche | derivados de cromano e seu uso como ligandos de receptor de 5-ht |
BRPI0515835A (pt) | 2004-12-21 | 2008-08-12 | Hoffmann La Roche | derivados de tetralina e de indano e seus usos |
CN100381398C (zh) * | 2005-07-29 | 2008-04-16 | 南京理工大学 | AlN-Si3N4-SiC陶瓷材料的制备方法 |
JP2009514828A (ja) | 2005-11-03 | 2009-04-09 | エフ.ホフマン−ラ ロシュ アーゲー | 5−ht6阻害剤としてのアリールスルホニルクロマン類、タンパク質キナーゼ阻害剤としてのインドリルマレイミド誘導体 |
EP2041079A1 (en) | 2006-06-20 | 2009-04-01 | F. Hoffmann-Roche AG | Arylsulfonyl naphthalene derivatives and uses thereof |
JP2009541248A (ja) | 2006-06-20 | 2009-11-26 | エフ.ホフマン−ラ ロシュ アーゲー | アリールスルホンアミジルテトラリン誘導体及びそれらの使用 |
EP2035370A2 (en) | 2006-06-20 | 2009-03-18 | F. Hoffmann-Roche AG | Tetralin and indane derivatives and uses thereof |
CN107540566A (zh) * | 2017-08-28 | 2018-01-05 | 江苏绿叶农化有限公司 | 一种炔苯酰草胺的制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0126367B1 (en) * | 1983-05-18 | 1994-10-12 | Beecham Group Plc | Chroman and chromene derivatives |
GB8414987D0 (en) * | 1984-06-12 | 1984-07-18 | Beecham Group Plc | Active compounds |
ATE56007T1 (de) * | 1984-06-22 | 1990-09-15 | Beecham Group Plc | Wirksame benzopyranverbindungen. |
DE3583780D1 (de) * | 1984-08-31 | 1991-09-19 | Otsuka Pharma Co Ltd | 2,3-dihydro-1h-inden-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
PT89205B (pt) * | 1987-12-14 | 1993-06-30 | Beecham Group Plc | Processo para a preparacao de derivados de indano |
GB8730052D0 (en) * | 1987-12-23 | 1988-02-03 | Beecham Group Plc | Novel compounds |
US4988723A (en) * | 1988-06-02 | 1991-01-29 | Fujisawa Pharmaceutical Co., Ltd. | Benzopyran derivatives and their use as anti-hypertensives |
EP0359537B1 (en) * | 1988-09-16 | 1996-06-26 | Beecham Group Plc | Benzopyran derivatives with antihypertensive activity |
ATE147732T1 (de) * | 1989-03-08 | 1997-02-15 | Merck Sharp & Dohme | Tetrahydroquinolin-derivate, verwendbar bei neurodegenerativen krankheiten |
AU632809B2 (en) * | 1989-05-25 | 1993-01-14 | Takeda Chemical Industries Ltd. | Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof |
US5140031A (en) * | 1989-05-31 | 1992-08-18 | E. R. Squibb & Sons, Inc. | Pyranyl cyanoguanidine derivatives |
-
1991
- 1991-10-15 US US07/776,921 patent/US5401848A/en not_active Expired - Fee Related
- 1991-10-25 ZA ZA918539A patent/ZA918539B/xx unknown
- 1991-10-30 IL IL99902A patent/IL99902A0/xx unknown
- 1991-10-31 CA CA002054637A patent/CA2054637A1/en not_active Abandoned
- 1991-11-06 IE IE386791A patent/IE913867A1/en not_active Application Discontinuation
- 1991-11-15 NZ NZ240615A patent/NZ240615A/en unknown
- 1991-11-21 AU AU88040/91A patent/AU637535B2/en not_active Ceased
- 1991-11-21 JP JP3306038A patent/JPH04352753A/ja not_active Withdrawn
- 1991-11-25 HU HU913664A patent/HU209470B/hu not_active IP Right Cessation
- 1991-11-25 RU SU915010280A patent/RU2058980C1/ru active
- 1991-11-25 NO NO914602A patent/NO176095C/no unknown
- 1991-11-25 KR KR1019910021074A patent/KR920009783A/ko not_active Application Discontinuation
- 1991-11-25 EP EP91310811A patent/EP0488616A1/en not_active Ceased
- 1991-11-25 FI FI915530A patent/FI915530A/fi not_active Application Discontinuation
- 1991-11-26 CN CN91111172A patent/CN1061961A/zh active Pending
- 1991-11-26 PT PT99605A patent/PT99605A/pt not_active Application Discontinuation
- 1991-11-26 PL PL91292536A patent/PL166983B1/pl unknown
Also Published As
Publication number | Publication date |
---|---|
NO176095C (no) | 1995-02-01 |
EP0488616A1 (en) | 1992-06-03 |
PL166983B1 (pl) | 1995-07-31 |
NZ240615A (en) | 1994-05-26 |
RU2058980C1 (ru) | 1996-04-27 |
KR920009783A (ko) | 1992-06-25 |
PL292536A1 (en) | 1992-09-21 |
AU637535B2 (en) | 1993-05-27 |
NO914602D0 (no) | 1991-11-25 |
FI915530A (fi) | 1992-05-27 |
HU209470B (en) | 1994-06-28 |
CN1061961A (zh) | 1992-06-17 |
NO914602L (no) | 1992-05-27 |
JPH04352753A (ja) | 1992-12-07 |
US5401848A (en) | 1995-03-28 |
HUT60467A (en) | 1992-09-28 |
IE913867A1 (en) | 1992-06-03 |
AU8804091A (en) | 1992-05-28 |
FI915530A0 (fi) | 1991-11-25 |
HU913664D0 (en) | 1992-02-28 |
IL99902A0 (en) | 1992-08-18 |
CA2054637A1 (en) | 1992-05-27 |
PT99605A (pt) | 1992-10-30 |
NO176095B (no) | 1994-10-24 |
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