IL99030A0 - 1,4-dihydropyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
1,4-dihydropyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL99030A0 IL99030A0 IL99030A IL9903091A IL99030A0 IL 99030 A0 IL99030 A0 IL 99030A0 IL 99030 A IL99030 A IL 99030A IL 9903091 A IL9903091 A IL 9903091A IL 99030 A0 IL99030 A0 IL 99030A0
- Authority
- IL
- Israel
- Prior art keywords
- processes
- preparation
- same
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9001752A NL9001752A (nl) | 1990-08-02 | 1990-08-02 | Nieuwe 1,4-dihydropyridinederivaten. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL99030A0 true IL99030A0 (en) | 1992-07-15 |
Family
ID=19857506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL99030A IL99030A0 (en) | 1990-08-02 | 1991-08-01 | 1,4-dihydropyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5378718A (xx) |
| EP (1) | EP0541634A1 (xx) |
| JP (1) | JPH05509094A (xx) |
| AU (1) | AU655192B2 (xx) |
| CA (1) | CA2088251A1 (xx) |
| FI (1) | FI930429A (xx) |
| IE (1) | IE912754A1 (xx) |
| IL (1) | IL99030A0 (xx) |
| NL (1) | NL9001752A (xx) |
| NO (1) | NO180084C (xx) |
| NZ (1) | NZ239234A (xx) |
| WO (1) | WO1992002503A1 (xx) |
| ZA (1) | ZA916058B (xx) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8142794A (en) * | 1993-11-17 | 1995-06-06 | Byk Nederland Bv | Use of substituted 1,4-dihydropyridine to reduce intraocular pressure |
| EP1108710A4 (en) * | 1998-07-23 | 2001-11-21 | Chen Ing Jun | GUAIACOXYPROPANOLAMINE WITH ALPHA / BETA ADRENERGIC INHIBIT ACTIVITY |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| US9012450B2 (en) | 2011-12-28 | 2015-04-21 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| PL2797416T3 (pl) | 2011-12-28 | 2017-12-29 | Global Blood Therapeutics, Inc. | Podstawione związki benzaldehydowe i sposoby ich zastosowania do zwiększania natlenienia tkanek |
| US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| KR20190041548A (ko) | 2013-03-15 | 2019-04-22 | 글로벌 블러드 테라퓨틱스, 인크. | 헤모글로빈 조정을 위한 화합물 및 이의 용도 |
| US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
| US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| MY191087A (en) | 2013-03-15 | 2022-05-30 | Global Blood Therapeutics Inc | Compounds and uses thereof for the modulation of hemoglobin |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| EA201591426A1 (ru) | 2013-03-15 | 2016-02-29 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| WO2014145040A1 (en) * | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| BR112015032160B1 (pt) | 2014-02-07 | 2021-11-30 | Global Blood Therapeutics, Inc | Ansolvato cristalino de composto, composição e composição farmacêutica |
| MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
| MA43373A (fr) | 2015-12-04 | 2018-10-10 | Global Blood Therapeutics Inc | Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde |
| TWI752307B (zh) | 2016-05-12 | 2022-01-11 | 美商全球血液治療公司 | 新穎化合物及製造化合物之方法 |
| TW202332423A (zh) | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
| US11014884B2 (en) | 2018-10-01 | 2021-05-25 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| GB1455502A (en) * | 1973-02-20 | 1976-11-10 | Yamanouchi Pharma Co Ltd | 1,4-dihydropyridine derivatives |
| JPS58185562A (ja) * | 1982-04-22 | 1983-10-29 | Taisho Pharmaceut Co Ltd | １，４−ジヒドロピリジン誘導体 |
| DE3248548A1 (de) * | 1982-12-29 | 1984-07-05 | Heinrich Mack Nachf., 7918 Illertissen | Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS6289662A (ja) * | 1985-06-14 | 1987-04-24 | Sankyo Co Ltd | １，４−ジヒドロピリジン誘導体 |
| DE3521761A1 (de) * | 1985-06-19 | 1987-01-02 | Bayer Ag | Neue 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
| AU1153088A (en) * | 1986-12-24 | 1988-07-27 | Boehringer Biochemia Robin S.P.A | New aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them |
| DE3833893A1 (de) * | 1988-10-05 | 1990-04-12 | Bayer Ag | Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte |
| DE3833892A1 (de) * | 1988-10-05 | 1990-04-12 | Bayer Ag | Basische 4-aryl-dhp-amide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
-
1990
- 1990-08-02 NL NL9001752A patent/NL9001752A/nl not_active Application Discontinuation
-
1991
- 1991-07-31 US US07/965,270 patent/US5378718A/en not_active Expired - Fee Related
- 1991-07-31 AU AU82801/91A patent/AU655192B2/en not_active Ceased
- 1991-07-31 WO PCT/EP1991/001442 patent/WO1992002503A1/en not_active Application Discontinuation
- 1991-07-31 JP JP3512770A patent/JPH05509094A/ja active Pending
- 1991-07-31 EP EP91913914A patent/EP0541634A1/en not_active Withdrawn
- 1991-07-31 CA CA002088251A patent/CA2088251A1/en not_active Abandoned
- 1991-08-01 ZA ZA916058A patent/ZA916058B/xx unknown
- 1991-08-01 IL IL99030A patent/IL99030A0/xx unknown
- 1991-08-02 IE IE275491A patent/IE912754A1/en unknown
- 1991-08-02 NZ NZ239234A patent/NZ239234A/en unknown
-
1993
- 1993-01-29 NO NO930306A patent/NO180084C/no unknown
- 1993-02-01 FI FI930429A patent/FI930429A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05509094A (ja) | 1993-12-16 |
| AU8280191A (en) | 1992-03-02 |
| CA2088251A1 (en) | 1992-02-03 |
| EP0541634A1 (en) | 1993-05-19 |
| NO180084C (no) | 1997-02-12 |
| NO930306L (no) | 1993-01-29 |
| US5378718A (en) | 1995-01-03 |
| NL9001752A (nl) | 1992-03-02 |
| ZA916058B (en) | 1992-06-24 |
| AU655192B2 (en) | 1994-12-08 |
| IE912754A1 (en) | 1992-02-12 |
| NZ239234A (en) | 1994-06-27 |
| NO180084B (no) | 1996-11-04 |
| WO1992002503A1 (en) | 1992-02-20 |
| FI930429A0 (fi) | 1993-02-01 |
| FI930429A (fi) | 1993-02-01 |
| NO930306D0 (no) | 1993-01-29 |
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