IL98726A - 5,5,6,7-Tetrahydro Amidazo] J-K-1, 4,5 [] 1, 4 [Benzodiazepine 2-) T. - Google Patents

5,5,6,7-Tetrahydro Amidazo] J-K-1, 4,5 [] 1, 4 [Benzodiazepine 2-) T.

Info

Publication number
IL98726A
IL98726A IL9872691A IL9872691A IL98726A IL 98726 A IL98726 A IL 98726A IL 9872691 A IL9872691 A IL 9872691A IL 9872691 A IL9872691 A IL 9872691A IL 98726 A IL98726 A IL 98726A
Authority
IL
Israel
Prior art keywords
formula
parts
hydrogen
reaction
compound
Prior art date
Application number
IL9872691A
Other languages
English (en)
Hebrew (he)
Other versions
IL98726A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL98726A0 publication Critical patent/IL98726A0/xx
Publication of IL98726A publication Critical patent/IL98726A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9872691A 1990-07-06 1991-07-04 5,5,6,7-Tetrahydro Amidazo] J-K-1, 4,5 [] 1, 4 [Benzodiazepine 2-) T. IL98726A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54934990A 1990-07-06 1990-07-06

Publications (2)

Publication Number Publication Date
IL98726A0 IL98726A0 (en) 1992-07-15
IL98726A true IL98726A (en) 1996-01-31

Family

ID=24192641

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9872691A IL98726A (en) 1990-07-06 1991-07-04 5,5,6,7-Tetrahydro Amidazo] J-K-1, 4,5 [] 1, 4 [Benzodiazepine 2-) T.

Country Status (29)

Country Link
EP (1) EP0538297B9 (sh)
JP (1) JPH05508632A (sh)
CN (1) CN1034122C (sh)
AP (1) AP262A (sh)
AT (1) ATE205848T1 (sh)
AU (1) AU644192B2 (sh)
CA (1) CA2086547A1 (sh)
CZ (1) CZ279900B6 (sh)
DE (1) DE69132738T2 (sh)
DK (1) DK0538297T3 (sh)
ES (1) ES2164044T3 (sh)
FI (1) FI930024A (sh)
HU (1) HUT68382A (sh)
IE (1) IE912363A1 (sh)
IL (1) IL98726A (sh)
MA (1) MA22205A1 (sh)
MX (1) MX9100103A (sh)
MY (1) MY106786A (sh)
NO (1) NO300420B1 (sh)
NZ (1) NZ238664A (sh)
OA (1) OA09769A (sh)
PL (3) PL169662B1 (sh)
PT (1) PT98225B (sh)
SK (1) SK278442B6 (sh)
TN (1) TNSN91055A1 (sh)
TW (1) TW211014B (sh)
WO (1) WO1992000979A1 (sh)
YU (1) YU48176B (sh)
ZA (1) ZA915239B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
AU4079593A (en) * 1992-05-13 1993-12-13 Wellcome Foundation Limited, The Therapeutic combinations
US5519021A (en) * 1992-08-07 1996-05-21 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
US6420357B1 (en) 1997-12-23 2002-07-16 Instituto Biomar, S.A. Cytotoxic alkaloid derivatives including Asmarine A and B isolated from a sponge

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
NZ235137A (en) * 1989-09-13 1992-02-25 Janssen Pharmaceutica Nv Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
DE4036552C1 (sh) * 1990-11-16 1992-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim, De

Also Published As

Publication number Publication date
NO924853L (no) 1992-12-15
MY106786A (en) 1995-07-31
DE69132738D1 (de) 2001-10-25
PL169662B1 (en) 1996-08-30
TNSN91055A1 (fr) 1992-10-25
PT98225A (pt) 1992-05-29
ES2164044T3 (es) 2002-02-16
YU48176B (sh) 1997-07-31
CZ279900B6 (cs) 1995-08-16
AP9100289A0 (en) 1991-07-31
HU9300011D0 (en) 1993-04-28
ATE205848T1 (de) 2001-10-15
PL168320B1 (pl) 1996-02-29
JPH05508632A (ja) 1993-12-02
TW211014B (sh) 1993-08-11
CS206591A3 (en) 1992-03-18
MX9100103A (es) 1992-02-28
OA09769A (fr) 1993-11-30
HUT68382A (en) 1995-06-28
AP262A (en) 1993-06-03
NO300420B1 (no) 1997-05-26
CN1034122C (zh) 1997-02-26
EP0538297B1 (en) 2001-09-19
WO1992000979A1 (en) 1992-01-23
DE69132738T2 (de) 2002-07-04
FI930024A0 (fi) 1993-01-05
MA22205A1 (fr) 1992-04-01
SK278442B6 (en) 1997-05-07
IE912363A1 (en) 1992-01-15
FI930024A (fi) 1993-01-05
CA2086547A1 (en) 1992-01-07
IL98726A0 (en) 1992-07-15
NZ238664A (en) 1992-12-23
EP0538297A1 (en) 1993-04-28
PT98225B (pt) 1998-12-31
PL169613B1 (pl) 1996-08-30
AU644192B2 (en) 1993-12-02
YU119491A (sh) 1994-06-10
CN1057840A (zh) 1992-01-15
AU8068391A (en) 1992-02-04
ZA915239B (en) 1993-03-31
PL297379A1 (sh) 1992-07-13
EP0538297B9 (en) 2002-10-16
DK0538297T3 (da) 2001-12-27
NO924853D0 (no) 1992-12-15

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AP262A (en) Novel antiviral tetrahydroimidazo (1,4) benzodiazepin-2-(thi) ones.
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Legal Events

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