DE69132738D1 - Antivirale tetrahydroimidazo[1,4]benzodiazepin-2-(thio)one - Google Patents

Antivirale tetrahydroimidazo[1,4]benzodiazepin-2-(thio)one

Info

Publication number
DE69132738D1
DE69132738D1 DE69132738T DE69132738T DE69132738D1 DE 69132738 D1 DE69132738 D1 DE 69132738D1 DE 69132738 T DE69132738 T DE 69132738T DE 69132738 T DE69132738 T DE 69132738T DE 69132738 D1 DE69132738 D1 DE 69132738D1
Authority
DE
Germany
Prior art keywords
benzodiazepine
thio
tetrahydroimidazo
antiviral
antiviral tetrahydroimidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69132738T
Other languages
English (en)
Other versions
DE69132738T2 (de
Inventor
Joseph Kukla
Joseph Breslin
Herman Raeymaekers
Gelder Ludovicus Van
Adriaan Janssen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE69132738D1 publication Critical patent/DE69132738D1/de
Publication of DE69132738T2 publication Critical patent/DE69132738T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69132738T 1990-07-06 1991-06-28 Antivirale tetrahydroimidazo[1,4]benzodiazepin-2-(thio)one Expired - Fee Related DE69132738T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54934990A 1990-07-06 1990-07-06
PCT/EP1991/001224 WO1992000979A1 (en) 1990-07-06 1991-06-28 Antiviral tetrahydroimidazo[1,4]benzodiazepin-2-(thio)ones

Publications (2)

Publication Number Publication Date
DE69132738D1 true DE69132738D1 (de) 2001-10-25
DE69132738T2 DE69132738T2 (de) 2002-07-04

Family

ID=24192641

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132738T Expired - Fee Related DE69132738T2 (de) 1990-07-06 1991-06-28 Antivirale tetrahydroimidazo[1,4]benzodiazepin-2-(thio)one

Country Status (29)

Country Link
EP (1) EP0538297B9 (de)
JP (1) JPH05508632A (de)
CN (1) CN1034122C (de)
AP (1) AP262A (de)
AT (1) ATE205848T1 (de)
AU (1) AU644192B2 (de)
CA (1) CA2086547A1 (de)
CZ (1) CZ279900B6 (de)
DE (1) DE69132738T2 (de)
DK (1) DK0538297T3 (de)
ES (1) ES2164044T3 (de)
FI (1) FI930024A0 (de)
HU (1) HUT68382A (de)
IE (1) IE912363A1 (de)
IL (1) IL98726A (de)
MA (1) MA22205A1 (de)
MX (1) MX9100103A (de)
MY (1) MY106786A (de)
NO (1) NO300420B1 (de)
NZ (1) NZ238664A (de)
OA (1) OA09769A (de)
PL (3) PL169662B1 (de)
PT (1) PT98225B (de)
SK (1) SK278442B6 (de)
TN (1) TNSN91055A1 (de)
TW (1) TW211014B (de)
WO (1) WO1992000979A1 (de)
YU (1) YU48176B (de)
ZA (1) ZA915239B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
AU4079593A (en) * 1992-05-13 1993-12-13 Wellcome Foundation Limited, The Therapeutic combinations
US5519021A (en) * 1992-08-07 1996-05-21 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
US6420357B1 (en) 1997-12-23 2002-07-16 Instituto Biomar, S.A. Cytotoxic alkaloid derivatives including Asmarine A and B isolated from a sponge

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them
NZ235137A (en) * 1989-09-13 1992-02-25 Janssen Pharmaceutica Nv Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
DE4036552C1 (de) * 1990-11-16 1992-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim, De

Also Published As

Publication number Publication date
AU644192B2 (en) 1993-12-02
NO300420B1 (no) 1997-05-26
NO924853D0 (no) 1992-12-15
IE912363A1 (en) 1992-01-15
CS206591A3 (en) 1992-03-18
IL98726A0 (en) 1992-07-15
EP0538297B9 (de) 2002-10-16
PL168320B1 (pl) 1996-02-29
PL169613B1 (pl) 1996-08-30
NO924853L (no) 1992-12-15
YU119491A (sh) 1994-06-10
CZ279900B6 (cs) 1995-08-16
AP9100289A0 (en) 1991-07-31
SK278442B6 (en) 1997-05-07
FI930024A (fi) 1993-01-05
ZA915239B (en) 1993-03-31
AU8068391A (en) 1992-02-04
AP262A (en) 1993-06-03
TW211014B (de) 1993-08-11
IL98726A (en) 1996-01-31
CA2086547A1 (en) 1992-01-07
PL169662B1 (en) 1996-08-30
EP0538297B1 (de) 2001-09-19
NZ238664A (en) 1992-12-23
CN1034122C (zh) 1997-02-26
MA22205A1 (fr) 1992-04-01
DE69132738T2 (de) 2002-07-04
HU9300011D0 (en) 1993-04-28
DK0538297T3 (da) 2001-12-27
MY106786A (en) 1995-07-31
YU48176B (sh) 1997-07-31
ES2164044T3 (es) 2002-02-16
MX9100103A (es) 1992-02-28
HUT68382A (en) 1995-06-28
EP0538297A1 (de) 1993-04-28
ATE205848T1 (de) 2001-10-15
OA09769A (fr) 1993-11-30
WO1992000979A1 (en) 1992-01-23
FI930024A0 (fi) 1993-01-05
PT98225B (pt) 1998-12-31
TNSN91055A1 (fr) 1992-10-25
CN1057840A (zh) 1992-01-15
PL297379A1 (de) 1992-07-13
JPH05508632A (ja) 1993-12-02
PT98225A (pt) 1992-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee