IL98506A - Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
IL98506A
IL98506A IL9850691A IL9850691A IL98506A IL 98506 A IL98506 A IL 98506A IL 9850691 A IL9850691 A IL 9850691A IL 9850691 A IL9850691 A IL 9850691A IL 98506 A IL98506 A IL 98506A
Authority
IL
Israel
Prior art keywords
alkoxy
compound
alkanoyl
salt
preparation
Prior art date
Application number
IL9850691A
Other languages
English (en)
Other versions
IL98506A0 (en
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909013558A external-priority patent/GB9013558D0/en
Priority claimed from GB909023666A external-priority patent/GB9023666D0/en
Priority claimed from GB919101552A external-priority patent/GB9101552D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IL98506A0 publication Critical patent/IL98506A0/xx
Publication of IL98506A publication Critical patent/IL98506A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Stringed Musical Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL9850691A 1990-06-18 1991-06-14 Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them IL98506A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909013558A GB9013558D0 (en) 1990-06-18 1990-06-18 New polypeptide compound and a process for preparation thereof
GB909023666A GB9023666D0 (en) 1990-10-31 1990-10-31 Polypeptide compound and a process for preparation thereof
GB919101552A GB9101552D0 (en) 1991-01-24 1991-01-24 New polypeptide compound and a process for preparation thereof

Publications (2)

Publication Number Publication Date
IL98506A0 IL98506A0 (en) 1992-07-15
IL98506A true IL98506A (en) 1996-09-12

Family

ID=27265144

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9850691A IL98506A (en) 1990-06-18 1991-06-14 Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US5376634A (de)
EP (2) EP0729974A1 (de)
JP (1) JP3307410B2 (de)
KR (1) KR100199535B1 (de)
CN (1) CN1040541C (de)
AT (1) ATE143671T1 (de)
AU (1) AU651347B2 (de)
CA (1) CA2044746C (de)
DE (1) DE69122432T2 (de)
DK (1) DK0462531T3 (de)
ES (1) ES2093658T3 (de)
FI (1) FI912873L (de)
GR (1) GR3021780T3 (de)
HU (2) HUT58108A (de)
IE (2) IE990233A1 (de)
IL (1) IL98506A (de)
NO (1) NO912347L (de)
OA (1) OA09369A (de)
PT (1) PT98023B (de)
RU (1) RU2108342C1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IL98506A (en) 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them
US5428009A (en) * 1990-07-16 1995-06-27 Merck & Co., Inc. Lipopeptide derivatives
USH1638H (en) * 1990-11-08 1997-03-04 Furuta; Takahisa Use of the polypeptide compound
US5385884A (en) * 1991-08-27 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
CA2161149A1 (en) * 1993-05-04 1994-11-10 James M. Balkovec Cyclohexapeptidyl aminoalkyl ethers
AU681119B2 (en) * 1993-05-17 1997-08-21 Fujisawa Pharmaceutical Co., Ltd. New polypeptide compound and a process for preparation thereof
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
JP2897427B2 (ja) * 1994-10-07 1999-05-31 藤沢薬品工業株式会社 抗微生物活性を有する環状ヘキサペプチド化合物
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
ATE206054T1 (de) * 1995-01-26 2001-10-15 Merck & Co Inc Neue fungizide cyclohexapeptide
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
EP1666587A1 (de) 1996-06-13 2006-06-07 Astellas Pharma Inc. Zyclische lipopeptid acylase
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
DE19728524A1 (de) * 1997-07-04 1999-01-07 Merck Patent Gmbh Cyclische Azapeptide
CA2320416A1 (en) 1998-02-09 1999-08-12 Fujisawa Pharmaceutical Co., Ltd. New compound
MY123337A (en) * 1998-05-11 2006-05-31 Takeda Chemical Industries Ltd Oxyiminoalkanoic acid derivatives.
EP1107981B1 (de) 1998-08-20 2005-01-26 Eli Lilly & Company Verfahren zur herstellung von ring-modifizierten zyklischen peptidanalogen
AU766091B2 (en) 1998-12-09 2003-10-09 Eli Lilly And Company Purification of echinocandin cyclopeptide compounds
EP1582204B1 (de) 1999-03-03 2013-09-25 Eli Lilly & Company Echinocandin pharmazeutische Zusammensetzungen enthaltend Mizellen bildende Tenside
JP2002538097A (ja) 1999-03-03 2002-11-12 イーライ リリー アンド カンパニー 薬学的経口ｅｃｂ処方物および組成物の作製方法
WO2000052037A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin/carbohydrate complexes
KR20020002476A (ko) 1999-03-03 2002-01-09 피터 지. 스트링거 결정질 에키노칸딘 암모늄염의 형성 및 음이온 교환
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
IL148427A0 (en) * 1999-09-03 2002-09-12 Sankyo Co Compound f-15078 and pharmaceutical compositions containing the same
WO2002068456A1 (en) * 2001-02-26 2002-09-06 Fujisawa Pharmaceutical Co., Ltd. Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs
KR20010098986A (ko) * 2001-07-27 2001-11-09 김종군 바르는 단열재(temp-coat)
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
CA2813330A1 (en) * 2010-09-29 2012-04-05 Shanghai Techwell Biopharmaceutical Co., Ltd. Process for purifying cyclolipopeptide compounds or the salts thereof
RU2538274C2 (ru) * 2010-09-30 2015-01-10 Шанхай Техвелл Биофармасьютикал Ко., Лтд. Способ очистки циклопептидных соединений или их солей
CN102533551B (zh) * 2010-12-15 2013-10-09 上海天伟生物制药有限公司 一种肽类抗生素的高产菌株及其制备方法和用途
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
US9132163B2 (en) 2011-04-20 2015-09-15 Xellia Pharmaceuticals Aps Method for purification of Micafungin
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102627689B (zh) 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN103387975A (zh) * 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途
CN116987153A (zh) * 2023-07-31 2023-11-03 上海天伟生物制药有限公司 一种高纯度棘白菌素药物杂质及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293484A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
EP0209061B1 (de) * 1985-07-17 1994-01-12 Hoechst Aktiengesellschaft Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel
DE3886001T2 (de) * 1987-10-07 1994-05-26 Merck & Co Inc Fungizides Fermentationsprodukt.
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
EP0450048A4 (en) * 1989-10-18 1992-12-02 City Of Hope Stable mammalian cell lines that express aromatase
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IL98506A (en) 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Cyclic peptide antibiotics processes for the preparation thereof and pharmaceutical compositions containing them
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii

Also Published As

Publication number Publication date
EP0462531A2 (de) 1991-12-27
ES2093658T3 (es) 1997-01-01
CA2044746C (en) 2001-08-07
PT98023A (pt) 1992-03-31
EP0462531A3 (en) 1992-11-04
KR100199535B1 (ko) 1999-06-15
CN1059729A (zh) 1992-03-25
US5376634A (en) 1994-12-27
FI912873A0 (fi) 1991-06-14
IE912046A1 (en) 1991-12-18
CA2044746A1 (en) 1991-12-19
EP0729974A1 (de) 1996-09-04
PT98023B (pt) 1998-11-30
OA09369A (en) 1992-09-15
NO912347L (no) 1991-12-19
CN1040541C (zh) 1998-11-04
NO912347D0 (no) 1991-06-17
GR3021780T3 (en) 1997-02-28
HUT58108A (en) 1992-01-28
KR920000788A (ko) 1992-01-29
DE69122432D1 (de) 1996-11-07
FI912873A7 (fi) 1991-12-19
JP3307410B2 (ja) 2002-07-24
RU2108342C1 (ru) 1998-04-10
FI912873L (fi) 1991-12-19
JPH04352799A (ja) 1992-12-07
DK0462531T3 (da) 1996-11-18
EP0462531B1 (de) 1996-10-02
IE990233A1 (en) 2000-11-15
ATE143671T1 (de) 1996-10-15
AU7843591A (en) 1992-01-16
AU651347B2 (en) 1994-07-21
HU211740A9 (en) 1995-12-28
IL98506A0 (en) 1992-07-15
HU912014D0 (en) 1991-12-30
DE69122432T2 (de) 1997-03-20

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Legal Events

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FF Patent granted
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