IL98476A0 - Dna coding for peptide capable of targeting a gene product into the plant vacuole and the peptide fragment encoded thereby - Google Patents

Dna coding for peptide capable of targeting a gene product into the plant vacuole and the peptide fragment encoded thereby

Info

Publication number
IL98476A0
IL98476A0 IL98476A IL9847691A IL98476A0 IL 98476 A0 IL98476 A0 IL 98476A0 IL 98476 A IL98476 A IL 98476A IL 9847691 A IL9847691 A IL 9847691A IL 98476 A0 IL98476 A0 IL 98476A0
Authority
IL
Israel
Prior art keywords
peptide
targeting
peptide fragments
gene product
dna coding
Prior art date
Application number
IL98476A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4223728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL98476(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL98476A0 publication Critical patent/IL98476A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8221—Transit peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/244—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2442—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01006—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01008—Endo-1,4-beta-xylanase (3.2.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01039—Glucan endo-1,3-beta-D-glucosidase (3.2.1.39)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01058—Glucan 1,3-beta-glucosidase (3.2.1.58)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01073—Licheninase (3.2.1.73)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Stereo-Broadcasting Methods (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Networks Using Active Elements (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IL98476A 1990-06-15 1991-06-13 Dna coding for peptide capable of targeting a gene product into the plant vacuole and the peptide fragment encoded thereby IL98476A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH200790 1990-06-15

Publications (1)

Publication Number Publication Date
IL98476A0 true IL98476A0 (en) 1992-07-15

Family

ID=4223728

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98476A IL98476A0 (en) 1990-06-15 1991-06-13 Dna coding for peptide capable of targeting a gene product into the plant vacuole and the peptide fragment encoded thereby

Country Status (15)

Country Link
US (1) US6054637A (fr)
EP (1) EP0462065B1 (fr)
JP (2) JPH04229182A (fr)
AT (1) ATE290087T1 (fr)
AU (1) AU653526B2 (fr)
BR (1) BR9102461A (fr)
CA (1) CA2044476A1 (fr)
DE (1) DE59109267D1 (fr)
ES (1) ES2235150T3 (fr)
HU (1) HUT58758A (fr)
IE (1) IE912039A1 (fr)
IL (1) IL98476A0 (fr)
NZ (1) NZ238533A (fr)
PT (1) PT97965B (fr)
TR (1) TR27970A (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418695A1 (fr) * 1989-09-13 1991-03-27 Ciba-Geigy Ag Séquence d'ADN régulatoire
DE4004800C2 (de) * 1990-02-13 2000-12-21 Aventis Cropscience Gmbh Im Habitus und Ertrag veränderte transgene Pflanzen
US6512166B1 (en) 1991-06-17 2003-01-28 Cornell Research Foundation, Inc. Combinations of fungal cell wall degrading enzyme and fungal cell membrane affecting compound
US6020540A (en) * 1993-04-14 2000-02-01 Cornell Research Foundation, Inc. Gene encoding endochitinase
FR2748480B1 (fr) * 1996-05-09 1998-09-04 Biocem Plantes transgeniques exprimant la glycoproteine g de la rage, et glycoproteines ainsi obtenues
IL155588A0 (en) 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
US20050032211A1 (en) * 1996-09-26 2005-02-10 Metabogal Ltd. Cell/tissue culturing device, system and method
US6972350B1 (en) * 1998-07-15 2005-12-06 The Horticulture And Food Research Institute Of New Zealand Pest-resistant plants comprising a construct encoding a vacuole targeting sequence and avidin or streptavidin
US6534265B1 (en) * 1999-02-16 2003-03-18 New Mexico State University Technology Transfer Corporation Oryzacystatin-I applications and methods
ATE440144T1 (de) * 2001-04-18 2009-09-15 Vlaams Interuniv Inst Biotech Die verwendung von abc transporter kodierenden genen zur stimulierung der herstellung von sekundärmetaboliten in biologischen zellen
US20030100945A1 (en) 2001-11-23 2003-05-29 Mindguard Ltd. Implantable intraluminal device and method of using same in treating aneurysms
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
US20100196345A1 (en) * 2003-04-27 2010-08-05 Protalix Production of high mannose proteins in plant culture
US9551003B2 (en) * 2006-09-13 2017-01-24 22Nd Century Limited, Llc Increasing levels of nicotinic alkaloids in plants
SI2150608T1 (en) 2007-05-07 2018-04-30 Protalix Ltd. An extensive disposable bioreactor
JP5279089B2 (ja) * 2007-07-03 2013-09-04 出光興産株式会社 ブタ浮腫病ワクチン
US9012719B2 (en) * 2009-02-06 2015-04-21 Syngenta Participations Ag Modification of multidomain enzyme for expression in plants
JP6617694B2 (ja) * 2016-12-12 2019-12-11 株式会社豊田中央研究所 植物体におけるゲノムシャッフリングのためのポリペプチド及びその利用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3711776A1 (de) * 1987-04-08 1988-10-27 Huels Chemische Werke Ag Verwendung von n-polyhydroxyalkylfettsaeureamiden als verdickungsmittel fuer fluessige waessrige tensidsysteme
EP0351924A3 (fr) * 1988-07-20 1991-04-03 Nickerson Seeds Limited Plantes transgéniques
CA1340685C (fr) * 1988-07-29 1999-07-27 Frederick Meins Sequences d'adn codant des polypeptides possedant une activite de beta-1,3-glucanase
AU4828490A (en) * 1988-12-16 1990-07-10 E.I. Du Pont De Nemours And Company Overexpression of chitinase in transgenic plants
DK0392225T3 (da) * 1989-03-24 2003-09-22 Syngenta Participations Ag Sygdomsresistente transgene planter
US5360726A (en) * 1989-09-12 1994-11-01 Board Of Trustees Operating Michigan State University Polypeptides enabling sorting of proteins to vacuoles in plants
EP0418695A1 (fr) * 1989-09-13 1991-03-27 Ciba-Geigy Ag Séquence d'ADN régulatoire
IL97020A (en) * 1990-01-30 2000-12-06 Mogen Int Recombinant polynucleotides comprising a chitinase gene and a glucanase gene
DE4004800C2 (de) * 1990-02-13 2000-12-21 Aventis Cropscience Gmbh Im Habitus und Ertrag veränderte transgene Pflanzen
JPH03246265A (ja) * 1990-02-22 1991-11-01 Kao Corp 脂肪酸アミドの製造方法
PH30997A (en) * 1990-03-12 1997-12-23 Ciba Geigy Antipathologenically effective compositions comprising lytic peptides and hydrolytic enzymes.
PT97826B (pt) * 1990-06-07 1998-10-30 Mogem International N V Processo para a preparacao de purificacao de uma proteina a partir de uma planta com um efeito inibidor num patogenio ou peste e de composicoes anti-fungos que as contem
EP0602179B1 (fr) * 1991-09-06 1999-06-30 The Procter & Gamble Company Compositions detergentes contenant du calcium et un amide d'acide gras polyhydroxy

Also Published As

Publication number Publication date
IE912039A1 (en) 1991-12-18
BR9102461A (pt) 1992-01-21
HU911994D0 (en) 1991-12-30
AU653526B2 (en) 1994-10-06
TR27970A (tr) 1995-11-07
EP0462065B1 (fr) 2005-03-02
HUT58758A (en) 1992-03-30
AU7841591A (en) 1991-12-19
EP0462065A2 (fr) 1991-12-18
EP0462065A3 (en) 1992-05-20
NZ238533A (en) 1993-09-27
ATE290087T1 (de) 2005-03-15
US6054637A (en) 2000-04-25
JP2003180354A (ja) 2003-07-02
JPH04229182A (ja) 1992-08-18
PT97965B (pt) 2004-02-27
ES2235150T3 (es) 2005-07-01
CA2044476A1 (fr) 1991-12-16
DE59109267D1 (de) 2005-04-07
PT97965A (pt) 1992-03-31

Similar Documents

Publication Publication Date Title
IL98476A0 (en) Dna coding for peptide capable of targeting a gene product into the plant vacuole and the peptide fragment encoded thereby
CA2345905A1 (fr) Polynucleotides optimises pour les vegetaux codant pour des proteines pesticides d'environ 15 kda et d'environ 45 kda
WO1999055868A3 (fr) Proteines fizz
ZA200201043B (en) Novel B7-4 molecules and uses thereof.
IL138930A0 (en) Il-17 homologies polypeptides and therapeutic uses thereof
IL94183A (en) cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
DK1218504T3 (da) GL50 molekyler og anvendelser deraf
WO1998021343B1 (fr) Genes codant des proteines de telomerase
JPS6420094A (en) Production and purification of protein fused to binding protein
IL103057A0 (en) Dna sequences encoding gelonin polypeptide
EP1009752A4 (fr) Nouvelles molecules de la famille des proteines de type tango-77 et utilisations de ces molecules
WO2006042719A3 (fr) Polypeptide presentant une activite de phytase et sequence nucleotidique codant ce polypeptide
CA2461443A1 (fr) Sequences d'acides nucleiques et d'acides amines codant des polypeptides de facteur viii a expresseur a haut rendement et leurs procedes d'utilisation
WO2000026244A3 (fr) Nouveau membre de la famille des facteurs de necrose des tumeurs, ligand du recepteur de la mort cellulaire (drl) et compositions et procedes correspondants
EP0546074A4 (en) Genetic material encoding igfbp-5
WO2000019988A8 (fr) NOUVELLES MOLECULES SPECIFIQUES DE Th2 ET LEURS UTILISATIONS
WO2000039149A3 (fr) Proteines secretees et leurs utilisations
WO1995008628A3 (fr) Acides nucleiques codant la merosine, fragments de merosine et utilisations de ceux-ci
SE9704141D0 (sv) New protein and nucleotide sequence, encoding said protein
EP0887410A3 (fr) ADN codant une protèine activant le plasminogène
EP0845536A3 (fr) Protéine à activité de l'acide éthylènediamine-N-N'-succinique: éthylènediamine lyase et ADN codant pour celle-ci
WO2001064919A3 (fr) 18036, une nouvelle protease semblable a la calpaïne, et utilisations de celle-la
ATE226256T1 (de) Antifungale proteine, dafür kodierende dna, und diese enthaltende wirtzelle
WO2001042286A3 (fr) Nouvelles molecules contenant des sequences nucleotidiques repetees riches en leucine et utilisations correspondantes
WO2002006331A3 (fr) 14087, nouvelle molecule de serine protease, et utilisations associees