IL97900A - Substituted 5-(2- ( ( 2-aryl- 2-hydroxyethyl) amino) propyl)-1, 3-benzodioxoles and a process for producing them - Google Patents

Substituted 5-(2- ( ( 2-aryl- 2-hydroxyethyl) amino) propyl)-1, 3-benzodioxoles and a process for producing them

Info

Publication number
IL97900A
IL97900A IL97900A IL9790091A IL97900A IL 97900 A IL97900 A IL 97900A IL 97900 A IL97900 A IL 97900A IL 9790091 A IL9790091 A IL 9790091A IL 97900 A IL97900 A IL 97900A
Authority
IL
Israel
Prior art keywords
hydrogen
group
alkyl
benzodioxoles
hydroxyethyl
Prior art date
Application number
IL97900A
Other languages
English (en)
Other versions
IL97900A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL97900A0 publication Critical patent/IL97900A0/xx
Publication of IL97900A publication Critical patent/IL97900A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
IL97900A 1990-05-04 1991-04-19 Substituted 5-(2- ( ( 2-aryl- 2-hydroxyethyl) amino) propyl)-1, 3-benzodioxoles and a process for producing them IL97900A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/519,192 US5061727A (en) 1990-05-04 1990-05-04 Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles

Publications (2)

Publication Number Publication Date
IL97900A0 IL97900A0 (en) 1992-06-21
IL97900A true IL97900A (en) 1997-04-15

Family

ID=24067267

Family Applications (1)

Application Number Title Priority Date Filing Date
IL97900A IL97900A (en) 1990-05-04 1991-04-19 Substituted 5-(2- ( ( 2-aryl- 2-hydroxyethyl) amino) propyl)-1, 3-benzodioxoles and a process for producing them

Country Status (22)

Country Link
US (1) US5061727A (pl)
EP (1) EP0455006B1 (pl)
JP (1) JPH05320153A (pl)
KR (1) KR0181178B1 (pl)
CN (1) CN1037348C (pl)
AT (1) ATE181914T1 (pl)
AU (1) AU639094B2 (pl)
CA (1) CA2041712A1 (pl)
CZ (1) CZ283420B6 (pl)
DE (1) DE69131412D1 (pl)
DK (1) DK0455006T3 (pl)
ES (1) ES2133273T3 (pl)
FI (1) FI94862C (pl)
HU (2) HU210596B (pl)
IE (1) IE911509A1 (pl)
IL (1) IL97900A (pl)
NO (1) NO177822C (pl)
NZ (1) NZ237992A (pl)
PL (1) PL165665B1 (pl)
PT (1) PT97540B (pl)
SG (1) SG47917A1 (pl)
ZA (1) ZA913366B (pl)

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ATE154935T1 (de) * 1993-06-14 1997-07-15 Pfizer Zweite amine als antidiabetische mittel und für die behandlung von fettleibigkeit
WO1995004047A1 (en) * 1993-07-31 1995-02-09 Smithkline Beecham Plc 2-benzoheterocyclyloxy or thiopropanolamine derivatives with adreno receptor agonist activity
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5629200A (en) * 1993-11-18 1997-05-13 Daicel Chemical Industries, Ltd. Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
US5438148A (en) * 1994-09-20 1995-08-01 American Cyanamid Company Process for the synthesis [R-(R*-,R*-)]-5-(3-chlorophenyl-3-[2-(3,4-dihydroxyphenyl)-1-methylethyl]-2
US5420291A (en) * 1993-12-09 1995-05-30 American Cyanamid Company Process improvement in the synthesis of [R-(R*,R*)1-5-(3-chlorophenyl)-3-[2-]-2-oxazolidinone
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US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
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US6043253A (en) * 1998-03-03 2000-03-28 Merck & Co., Inc. Fused piperidine substituted arylsulfonamides as β3-agonists
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WO2003024483A1 (fr) * 2001-09-11 2003-03-27 Fujisawa Pharmaceutical Co., Ltd. Potentialisateur d'effets inhibiteurs sur la frequence des mictions et l'incontinence urinaire
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US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
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GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
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Also Published As

Publication number Publication date
IE911509A1 (en) 1991-11-06
EP0455006B1 (en) 1999-07-07
HU210596B (en) 1995-05-29
AU639094B2 (en) 1993-07-15
KR0181178B1 (ko) 1999-03-20
IL97900A0 (en) 1992-06-21
HUT59918A (en) 1992-07-28
EP0455006A2 (en) 1991-11-06
NO911751L (no) 1991-11-05
ZA913366B (en) 1992-03-25
ES2133273T3 (es) 1999-09-16
ATE181914T1 (de) 1999-07-15
CN1056495A (zh) 1991-11-27
PT97540B (pt) 1998-08-31
SG47917A1 (en) 1998-04-17
FI912142A0 (fi) 1991-05-03
CN1037348C (zh) 1998-02-11
US5061727A (en) 1991-10-29
NO911751D0 (no) 1991-05-03
CS9101285A2 (en) 1991-12-17
HU911495D0 (en) 1991-11-28
PT97540A (pt) 1992-01-31
FI94862B (fi) 1995-07-31
PL290119A1 (en) 1992-07-27
FI912142L (fi) 1991-11-05
NO177822C (no) 1995-11-29
CA2041712A1 (en) 1991-11-05
KR910019999A (ko) 1991-12-19
DE69131412D1 (de) 1999-08-12
JPH05320153A (ja) 1993-12-03
NZ237992A (en) 1993-05-26
EP0455006A3 (en) 1992-04-01
HU211607A9 (en) 1995-12-28
PL165665B1 (pl) 1995-01-31
NO177822B (no) 1995-08-21
CZ283420B6 (cs) 1998-04-15
DK0455006T3 (da) 1999-11-22
FI94862C (fi) 1995-11-10
AU7607891A (en) 1991-11-07

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Legal Events

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