IL96841A - Preparations and method for the treatment of osteoporosis in mammals containing insulin-like growth factor I - Google Patents
Preparations and method for the treatment of osteoporosis in mammals containing insulin-like growth factor IInfo
- Publication number
- IL96841A IL96841A IL9684190A IL9684190A IL96841A IL 96841 A IL96841 A IL 96841A IL 9684190 A IL9684190 A IL 9684190A IL 9684190 A IL9684190 A IL 9684190A IL 96841 A IL96841 A IL 96841A
- Authority
- IL
- Israel
- Prior art keywords
- igf
- bone
- mammal
- composition
- mineral density
- Prior art date
Links
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title claims abstract description 79
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 title claims abstract description 78
- 208000001132 Osteoporosis Diseases 0.000 title claims abstract description 38
- 241000124008 Mammalia Species 0.000 title claims abstract description 34
- 239000000203 mixture Substances 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 title abstract description 17
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- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 39
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- 150000001875 compounds Chemical class 0.000 claims description 9
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46041690A | 1990-01-03 | 1990-01-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL96841A0 IL96841A0 (en) | 1991-09-16 |
| IL96841A true IL96841A (en) | 1996-05-14 |
Family
ID=23828617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9684190A IL96841A (en) | 1990-01-03 | 1990-12-31 | Preparations and method for the treatment of osteoporosis in mammals containing insulin-like growth factor I |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5646116A (ko) |
| EP (1) | EP0436469B1 (ko) |
| JP (1) | JP3053116B2 (ko) |
| KR (1) | KR100200995B1 (ko) |
| AT (1) | ATE118172T1 (ko) |
| AU (1) | AU629443B2 (ko) |
| CA (1) | CA2033469C (ko) |
| DE (1) | DE69016768T2 (ko) |
| DK (1) | DK0436469T3 (ko) |
| ES (1) | ES2067720T3 (ko) |
| GR (1) | GR3015490T3 (ko) |
| IE (1) | IE66240B1 (ko) |
| IL (1) | IL96841A (ko) |
| NZ (1) | NZ236618A (ko) |
| ZA (1) | ZA916B (ko) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE222117T1 (de) * | 1990-05-30 | 2002-08-15 | Harvard College | Kombination aus igf-i und tgf-beta zur knochenregenerierung |
| US5674844A (en) * | 1991-03-11 | 1997-10-07 | Creative Biomolecules, Inc. | Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases |
| US7056882B2 (en) | 1991-03-11 | 2006-06-06 | Curis, Inc. | Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases |
| US5118667A (en) * | 1991-05-03 | 1992-06-02 | Celtrix Pharmaceuticals, Inc. | Bone growth factors and inhibitors of bone resorption for promoting bone formation |
| US5202119A (en) * | 1991-06-28 | 1993-04-13 | Genentech, Inc. | Method of stimulating immune response |
| TW267102B (ko) * | 1992-03-13 | 1996-01-01 | Ciba Geigy | |
| JPH08500123A (ja) * | 1993-01-25 | 1996-01-09 | ザ ベス イスラエル ホスピタル アソシエイション | Ｉｇｆ−ｉ感受性細胞のバリヤー特性の修飾方法，診断方法及びスクリーニング方法 |
| EP0800530A4 (en) * | 1994-07-20 | 1998-12-02 | Celtrix Pharma | IGF / IGFBP COMPLEX FOR PROMOTING BONE TRAINING AND REGULATING BONE REMODELING |
| AU3545795A (en) * | 1994-09-08 | 1996-03-27 | Chiron Corporation | A method of improved production of insulin-like growth factor |
| US5728676A (en) * | 1994-09-08 | 1998-03-17 | Ciba-Geigy Corporation | Use of insulin-like growth factors I and II for inhibition of inflammatory response |
| US5622932A (en) * | 1995-05-05 | 1997-04-22 | Eli Lilly And Company | IGF-1 superagonists |
| US6048964A (en) * | 1995-12-12 | 2000-04-11 | Stryker Corporation | Compositions and therapeutic methods using morphogenic proteins and stimulatory factors |
| US7026292B1 (en) | 1995-12-12 | 2006-04-11 | Stryker Corporation | Compositions and therapeutic methods using morphogenic proteins and stimulatory factors |
| CN1220609A (zh) * | 1996-05-31 | 1999-06-23 | 诺沃挪第克公司 | 骨质疏松症周期性治疗中的生长激素组分和骨抗吸收剂 |
| US6025368A (en) * | 1997-02-25 | 2000-02-15 | Celtrix Pharmaceuticals, Inc. | Method for treating the symptoms of chronic stress-related disorders using IGF |
| US6015786A (en) * | 1997-02-25 | 2000-01-18 | Celtrix Pharmaceuticals, Inc. | Method for increasing sex steroid levels using IGF or IGF/IGFBP-3 |
| US6514937B1 (en) | 1997-02-25 | 2003-02-04 | Celtrix Pharmaceuticals, Inc. | Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3 |
| US6403764B1 (en) | 1999-01-06 | 2002-06-11 | Genentech, Inc. | Insulin-like growth factor-1 protein variants |
| US6627746B1 (en) | 1998-04-17 | 2003-09-30 | Exelixis, Inc. | Nucleic acids and proteins of C. elegans insulin-like genes and uses thereof |
| US6846496B1 (en) | 1999-10-15 | 2005-01-25 | Orion Corporation | Treatment of osteoporosis |
| WO2001072323A2 (en) | 2000-03-24 | 2001-10-04 | Genentech, Inc. | Use of insulin for the treatment of cartilagenous disorders |
| WO2001087323A2 (en) | 2000-05-16 | 2001-11-22 | Genentech, Inc. | Method for treating cartilage disorders |
| CA2347330C (en) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
| US7189233B2 (en) * | 2001-10-22 | 2007-03-13 | Surgrx, Inc. | Electrosurgical instrument |
| WO2005002590A1 (ja) * | 2003-07-01 | 2005-01-13 | Astellas Pharma Inc. | 骨量増加誘導剤 |
| WO2004084859A2 (en) * | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
| US20050171015A1 (en) * | 2003-10-31 | 2005-08-04 | Crabtree Gerald R. | Methods and agents for enhancing bone formation or preventing bone loss |
| US7998500B2 (en) | 2005-08-04 | 2011-08-16 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for women |
| US8202546B2 (en) | 2005-08-04 | 2012-06-19 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| US7901710B2 (en) | 2005-08-04 | 2011-03-08 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| US8263137B2 (en) | 2005-08-04 | 2012-09-11 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for women |
| US20080200425A1 (en) * | 2007-02-16 | 2008-08-21 | Kurtz Seymour J | Methods and compositions for regulating bone mineral density |
| WO2014143992A1 (en) * | 2013-03-15 | 2014-09-18 | University Of Rochester | Treating lysosomal storage disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE95236T1 (de) * | 1983-04-25 | 1993-10-15 | Chiron Corp | Hybrid-dns-synthesis von reifen insulinaehnlichen wachstumsfaktoren. |
| US4774091A (en) * | 1983-10-14 | 1988-09-27 | Sumitomo Pharmaceuticals Company, Ltd. | Long-term sustained-release preparation |
| ATE112684T1 (de) * | 1987-04-28 | 1994-10-15 | Boehringer Mannheim Gmbh | Verwendung von igf-ii zur behandlung von knochenkrankheiten. |
| US4876242A (en) * | 1987-09-21 | 1989-10-24 | Merck & Co., Inc. | Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast |
| JPH0649655B2 (ja) * | 1987-11-12 | 1994-06-29 | シェリング・コーポレーション | Ｇｍ‐ｃｓｆによる骨形成の促進 |
-
1990
- 1990-12-21 NZ NZ236618A patent/NZ236618A/en unknown
- 1990-12-27 DK DK90811032.3T patent/DK0436469T3/da active
- 1990-12-27 EP EP90811032A patent/EP0436469B1/en not_active Expired - Lifetime
- 1990-12-27 ES ES90811032T patent/ES2067720T3/es not_active Expired - Lifetime
- 1990-12-27 AU AU68532/90A patent/AU629443B2/en not_active Ceased
- 1990-12-27 AT AT90811032T patent/ATE118172T1/de not_active IP Right Cessation
- 1990-12-27 DE DE69016768T patent/DE69016768T2/de not_active Expired - Fee Related
- 1990-12-28 JP JP2418819A patent/JP3053116B2/ja not_active Expired - Fee Related
- 1990-12-31 IL IL9684190A patent/IL96841A/en not_active IP Right Cessation
- 1990-12-31 CA CA002033469A patent/CA2033469C/en not_active Expired - Fee Related
- 1990-12-31 KR KR1019900022587A patent/KR100200995B1/ko not_active IP Right Cessation
-
1991
- 1991-01-02 IE IE491A patent/IE66240B1/en not_active IP Right Cessation
- 1991-01-02 ZA ZA916A patent/ZA916B/xx unknown
-
1995
- 1995-03-01 US US08/396,884 patent/US5646116A/en not_active Expired - Fee Related
- 1995-03-20 GR GR950400621T patent/GR3015490T3/el unknown
-
1996
- 1996-12-30 US US08/774,510 patent/US6174857B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA916B (en) | 1991-08-28 |
| AU629443B2 (en) | 1992-10-01 |
| IE66240B1 (en) | 1995-12-13 |
| AU6853290A (en) | 1991-07-04 |
| CA2033469C (en) | 2003-01-28 |
| DK0436469T3 (da) | 1995-04-03 |
| EP0436469B1 (en) | 1995-02-08 |
| IE910004A1 (en) | 1991-07-17 |
| JPH04235135A (ja) | 1992-08-24 |
| NZ236618A (en) | 1997-06-24 |
| ATE118172T1 (de) | 1995-02-15 |
| IL96841A0 (en) | 1991-09-16 |
| DE69016768T2 (de) | 1995-06-14 |
| EP0436469A1 (en) | 1991-07-10 |
| US6174857B1 (en) | 2001-01-16 |
| KR910021243A (ko) | 1991-12-20 |
| CA2033469A1 (en) | 1991-07-04 |
| GR3015490T3 (en) | 1995-06-30 |
| JP3053116B2 (ja) | 2000-06-19 |
| KR100200995B1 (ko) | 1999-06-15 |
| ES2067720T3 (es) | 1995-04-01 |
| US5646116A (en) | 1997-07-08 |
| DE69016768D1 (de) | 1995-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| HC | Change of name of proprietor(s) | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |