IL95717A - Process for the chemical separation of W (- 1,3-dimethyl oxaindolylethylamines converted into 5-alkoxy - Google Patents

Process for the chemical separation of W (- 1,3-dimethyl oxaindolylethylamines converted into 5-alkoxy

Info

Publication number
IL95717A
IL95717A IL9571790A IL9571790A IL95717A IL 95717 A IL95717 A IL 95717A IL 9571790 A IL9571790 A IL 9571790A IL 9571790 A IL9571790 A IL 9571790A IL 95717 A IL95717 A IL 95717A
Authority
IL
Israel
Prior art keywords
enantiomers
mixture
acid
tartaric acid
precipitate
Prior art date
Application number
IL9571790A
Other languages
English (en)
Hebrew (he)
Other versions
IL95717A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL95717A0 publication Critical patent/IL95717A0/xx
Publication of IL95717A publication Critical patent/IL95717A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
IL9571790A 1989-09-19 1990-09-17 Process for the chemical separation of W (- 1,3-dimethyl oxaindolylethylamines converted into 5-alkoxy IL95717A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40921389A 1989-09-19 1989-09-19

Publications (2)

Publication Number Publication Date
IL95717A0 IL95717A0 (en) 1991-06-30
IL95717A true IL95717A (en) 1994-10-21

Family

ID=23619520

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9571790A IL95717A (en) 1989-09-19 1990-09-17 Process for the chemical separation of W (- 1,3-dimethyl oxaindolylethylamines converted into 5-alkoxy

Country Status (17)

Country Link
US (1) US5387695A (ko)
EP (1) EP0418770B1 (ko)
JP (1) JPH0757746B2 (ko)
KR (1) KR0165670B1 (ko)
AT (1) ATE125254T1 (ko)
AU (1) AU626458B2 (ko)
CA (1) CA2025593A1 (ko)
DE (1) DE69020989T2 (ko)
DK (1) DK0418770T3 (ko)
ES (1) ES2075102T3 (ko)
FI (1) FI95030C (ko)
IE (1) IE67640B1 (ko)
IL (1) IL95717A (ko)
NO (1) NO174252C (ko)
NZ (1) NZ235333A (ko)
PT (1) PT95340B (ko)
ZA (1) ZA907424B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5840915A (en) * 1990-01-22 1998-11-24 Hoechst Marion Roussel, Inc. Process for the enatioselective synthesis of intermediates used
DK0438796T3 (da) * 1990-01-22 1999-05-25 Hoechst Marion Roussel Inc Fremgangsmåde til enantioselektiv syntese af alkylerede oxindoler, som anvendes som mellemprodukter ved fremstilling af phy
US5521320A (en) * 1990-01-22 1996-05-28 Hoechst-Roussel Pharmaceuticals Incorporated Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers
WO2016133317A1 (ko) 2015-02-17 2016-08-25 (주)아모레퍼시픽 Ｎ-[4-(1-아미노에틸)-페닐]-술폰아미드 유도체의 카이랄 분할 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5274117A (en) * 1990-01-22 1993-12-28 Hoechst-Roussel Pharmaceuticals, Inc. Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
DK0438796T3 (da) * 1990-01-22 1999-05-25 Hoechst Marion Roussel Inc Fremgangsmåde til enantioselektiv syntese af alkylerede oxindoler, som anvendes som mellemprodukter ved fremstilling af phy

Also Published As

Publication number Publication date
IL95717A0 (en) 1991-06-30
EP0418770A3 (en) 1991-11-27
PT95340B (pt) 1997-06-30
FI95030C (fi) 1995-12-11
JPH0757746B2 (ja) 1995-06-21
JPH03167172A (ja) 1991-07-19
DE69020989T2 (de) 1996-02-08
NO174252B (no) 1993-12-27
FI95030B (fi) 1995-08-31
ATE125254T1 (de) 1995-08-15
DE69020989D1 (de) 1995-08-24
DK0418770T3 (da) 1995-10-30
EP0418770B1 (en) 1995-07-19
IE67640B1 (en) 1996-04-17
NO174252C (no) 1994-04-06
ZA907424B (en) 1991-06-26
ES2075102T3 (es) 1995-10-01
AU626458B2 (en) 1992-07-30
AU6262990A (en) 1991-03-28
EP0418770A2 (en) 1991-03-27
NZ235333A (en) 1992-03-26
NO904067L (no) 1991-03-20
NO904067D0 (no) 1990-09-18
KR910006229A (ko) 1991-04-27
US5387695A (en) 1995-02-07
KR0165670B1 (ko) 1999-01-15
FI904562A0 (fi) 1990-09-17
CA2025593A1 (en) 1991-03-20
PT95340A (pt) 1991-05-22
IE903374A1 (en) 1991-04-10

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
RH Patent void