DK0418770T3 - Fremgangsmåde til kemisk spaltning af 5-alkoxysubstituerede (+-)-1,3-dimethyloxindolylethylaminer - Google Patents

Fremgangsmåde til kemisk spaltning af 5-alkoxysubstituerede (+-)-1,3-dimethyloxindolylethylaminer

Info

Publication number
DK0418770T3
DK0418770T3 DK90117821.0T DK90117821T DK0418770T3 DK 0418770 T3 DK0418770 T3 DK 0418770T3 DK 90117821 T DK90117821 T DK 90117821T DK 0418770 T3 DK0418770 T3 DK 0418770T3
Authority
DK
Denmark
Prior art keywords
tartaric acid
enantiomers
acid
dimethyloxindolylethylamines
alkoxy substituted
Prior art date
Application number
DK90117821.0T
Other languages
English (en)
Inventor
Thomas Bing Kin Dr Lee
George S K Wong
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of DK0418770T3 publication Critical patent/DK0418770T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK90117821.0T 1989-09-19 1990-09-15 Fremgangsmåde til kemisk spaltning af 5-alkoxysubstituerede (+-)-1,3-dimethyloxindolylethylaminer DK0418770T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40921389A 1989-09-19 1989-09-19

Publications (1)

Publication Number Publication Date
DK0418770T3 true DK0418770T3 (da) 1995-10-30

Family

ID=23619520

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90117821.0T DK0418770T3 (da) 1989-09-19 1990-09-15 Fremgangsmåde til kemisk spaltning af 5-alkoxysubstituerede (+-)-1,3-dimethyloxindolylethylaminer

Country Status (17)

Country Link
US (1) US5387695A (da)
EP (1) EP0418770B1 (da)
JP (1) JPH0757746B2 (da)
KR (1) KR0165670B1 (da)
AT (1) ATE125254T1 (da)
AU (1) AU626458B2 (da)
CA (1) CA2025593A1 (da)
DE (1) DE69020989T2 (da)
DK (1) DK0418770T3 (da)
ES (1) ES2075102T3 (da)
FI (1) FI95030C (da)
IE (1) IE67640B1 (da)
IL (1) IL95717A (da)
NO (1) NO174252C (da)
NZ (1) NZ235333A (da)
PT (1) PT95340B (da)
ZA (1) ZA907424B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5521320A (en) * 1990-01-22 1996-05-28 Hoechst-Roussel Pharmaceuticals Incorporated Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
US5840915A (en) * 1990-01-22 1998-11-24 Hoechst Marion Roussel, Inc. Process for the enatioselective synthesis of intermediates used
DE69032595T2 (de) * 1990-01-22 1999-03-25 Hoechst Marion Roussel Inc Verfahren zur enantioselektiven Synthese alkylierter Oxindole zur Verwendung als Zwischenprodukte bei der Herstellung von Physostigminen
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers
KR101791119B1 (ko) * 2015-02-17 2017-11-20 (주)아모레퍼시픽 N-[4-(1-아미노에틸)-페닐]-술폰아미드 유도체의 카이랄 분할 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
DE69032595T2 (de) * 1990-01-22 1999-03-25 Hoechst Marion Roussel Inc Verfahren zur enantioselektiven Synthese alkylierter Oxindole zur Verwendung als Zwischenprodukte bei der Herstellung von Physostigminen
US5274117A (en) * 1990-01-22 1993-12-28 Hoechst-Roussel Pharmaceuticals, Inc. Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine

Also Published As

Publication number Publication date
US5387695A (en) 1995-02-07
DE69020989D1 (de) 1995-08-24
FI904562A0 (fi) 1990-09-17
FI95030C (fi) 1995-12-11
IE903374A1 (en) 1991-04-10
NO904067L (no) 1991-03-20
AU626458B2 (en) 1992-07-30
EP0418770B1 (en) 1995-07-19
ATE125254T1 (de) 1995-08-15
PT95340B (pt) 1997-06-30
FI95030B (fi) 1995-08-31
JPH0757746B2 (ja) 1995-06-21
AU6262990A (en) 1991-03-28
KR910006229A (ko) 1991-04-27
NO904067D0 (no) 1990-09-18
NO174252B (no) 1993-12-27
NO174252C (no) 1994-04-06
EP0418770A3 (en) 1991-11-27
IE67640B1 (en) 1996-04-17
IL95717A (en) 1994-10-21
JPH03167172A (ja) 1991-07-19
KR0165670B1 (ko) 1999-01-15
EP0418770A2 (en) 1991-03-27
PT95340A (pt) 1991-05-22
ES2075102T3 (es) 1995-10-01
IL95717A0 (en) 1991-06-30
ZA907424B (en) 1991-06-26
NZ235333A (en) 1992-03-26
DE69020989T2 (de) 1996-02-08
CA2025593A1 (en) 1991-03-20

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