ZA907424B - Process for the chemical resolution of 5-alkoxy-substituted(+_)-1,3-dimethyloxindolylethylamines - Google Patents

Process for the chemical resolution of 5-alkoxy-substituted(+_)-1,3-dimethyloxindolylethylamines

Info

Publication number
ZA907424B
ZA907424B ZA907424A ZA907424A ZA907424B ZA 907424 B ZA907424 B ZA 907424B ZA 907424 A ZA907424 A ZA 907424A ZA 907424 A ZA907424 A ZA 907424A ZA 907424 B ZA907424 B ZA 907424B
Authority
ZA
South Africa
Prior art keywords
tartaric acid
enantiomers
acid
dimethyloxindolylethylamines
alkoxy
Prior art date
Application number
ZA907424A
Other languages
English (en)
Inventor
Thomas B K Lee
B K Lee Thomas
George S K Wong
S K Wong George
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA907424B publication Critical patent/ZA907424B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
ZA907424A 1989-09-19 1990-09-18 Process for the chemical resolution of 5-alkoxy-substituted(+_)-1,3-dimethyloxindolylethylamines ZA907424B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40921389A 1989-09-19 1989-09-19

Publications (1)

Publication Number Publication Date
ZA907424B true ZA907424B (en) 1991-06-26

Family

ID=23619520

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA907424A ZA907424B (en) 1989-09-19 1990-09-18 Process for the chemical resolution of 5-alkoxy-substituted(+_)-1,3-dimethyloxindolylethylamines

Country Status (17)

Country Link
US (1) US5387695A (xx)
EP (1) EP0418770B1 (xx)
JP (1) JPH0757746B2 (xx)
KR (1) KR0165670B1 (xx)
AT (1) ATE125254T1 (xx)
AU (1) AU626458B2 (xx)
CA (1) CA2025593A1 (xx)
DE (1) DE69020989T2 (xx)
DK (1) DK0418770T3 (xx)
ES (1) ES2075102T3 (xx)
FI (1) FI95030C (xx)
IE (1) IE67640B1 (xx)
IL (1) IL95717A (xx)
NO (1) NO174252C (xx)
NZ (1) NZ235333A (xx)
PT (1) PT95340B (xx)
ZA (1) ZA907424B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5840915A (en) * 1990-01-22 1998-11-24 Hoechst Marion Roussel, Inc. Process for the enatioselective synthesis of intermediates used
DK0438796T3 (da) * 1990-01-22 1999-05-25 Hoechst Marion Roussel Inc Fremgangsmåde til enantioselektiv syntese af alkylerede oxindoler, som anvendes som mellemprodukter ved fremstilling af phy
US5521320A (en) * 1990-01-22 1996-05-28 Hoechst-Roussel Pharmaceuticals Incorporated Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers
WO2016133317A1 (ko) 2015-02-17 2016-08-25 (주)아모레퍼시픽 Ｎ-[4-(1-아미노에틸)-페닐]-술폰아미드 유도체의 카이랄 분할 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5274117A (en) * 1990-01-22 1993-12-28 Hoechst-Roussel Pharmaceuticals, Inc. Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
DK0438796T3 (da) * 1990-01-22 1999-05-25 Hoechst Marion Roussel Inc Fremgangsmåde til enantioselektiv syntese af alkylerede oxindoler, som anvendes som mellemprodukter ved fremstilling af phy

Also Published As

Publication number Publication date
IL95717A0 (en) 1991-06-30
EP0418770A3 (en) 1991-11-27
PT95340B (pt) 1997-06-30
FI95030C (fi) 1995-12-11
JPH0757746B2 (ja) 1995-06-21
JPH03167172A (ja) 1991-07-19
DE69020989T2 (de) 1996-02-08
NO174252B (no) 1993-12-27
FI95030B (fi) 1995-08-31
ATE125254T1 (de) 1995-08-15
DE69020989D1 (de) 1995-08-24
DK0418770T3 (da) 1995-10-30
EP0418770B1 (en) 1995-07-19
IE67640B1 (en) 1996-04-17
NO174252C (no) 1994-04-06
ES2075102T3 (es) 1995-10-01
AU626458B2 (en) 1992-07-30
AU6262990A (en) 1991-03-28
EP0418770A2 (en) 1991-03-27
NZ235333A (en) 1992-03-26
NO904067L (no) 1991-03-20
NO904067D0 (no) 1990-09-18
IL95717A (en) 1994-10-21
KR910006229A (ko) 1991-04-27
US5387695A (en) 1995-02-07
KR0165670B1 (ko) 1999-01-15
FI904562A0 (fi) 1990-09-17
CA2025593A1 (en) 1991-03-20
PT95340A (pt) 1991-05-22
IE903374A1 (en) 1991-04-10

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