IL95564A0 - Cephalosporin derivatives - Google Patents

Cephalosporin derivatives

Info

Publication number
IL95564A0
IL95564A0 IL95564A IL9556490A IL95564A0 IL 95564 A0 IL95564 A0 IL 95564A0 IL 95564 A IL95564 A IL 95564A IL 9556490 A IL9556490 A IL 9556490A IL 95564 A0 IL95564 A0 IL 95564A0
Authority
IL
Israel
Prior art keywords
cephalosporin derivatives
preparation
optionally substituted
antibacterial
aminopyridiniumthiomethyl
Prior art date
Application number
IL95564A
Other languages
English (en)
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898919946A external-priority patent/GB8919946D0/en
Priority claimed from GB898919945A external-priority patent/GB8919945D0/en
Priority claimed from GB909006728A external-priority patent/GB9006728D0/en
Priority claimed from GB909010265A external-priority patent/GB9010265D0/en
Priority claimed from GB909010299A external-priority patent/GB9010299D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of IL95564A0 publication Critical patent/IL95564A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Sub-Exchange Stations And Push- Button Telephones (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Jib Cranes (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IL95564A 1989-09-04 1990-09-03 Cephalosporin derivatives IL95564A0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB898919946A GB8919946D0 (en) 1989-09-04 1989-09-04 Novel compounds
GB898919945A GB8919945D0 (en) 1989-09-04 1989-09-04 Novel compounds
GB909006728A GB9006728D0 (en) 1990-03-26 1990-03-26 Novel compounds
GB909010265A GB9010265D0 (en) 1990-05-08 1990-05-08 Novel compounds
GB909010299A GB9010299D0 (en) 1990-05-08 1990-05-08 Novel compounds

Publications (1)

Publication Number Publication Date
IL95564A0 true IL95564A0 (en) 1991-06-30

Family

ID=27516935

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95564A IL95564A0 (en) 1989-09-04 1990-09-03 Cephalosporin derivatives

Country Status (18)

Country Link
EP (1) EP0416814B1 (fr)
JP (1) JP2874987B2 (fr)
CN (1) CN1038327C (fr)
AT (1) ATE216701T1 (fr)
AU (1) AU635561B2 (fr)
CA (1) CA2024399C (fr)
DE (1) DE69033952T2 (fr)
DK (1) DK0416814T3 (fr)
ES (1) ES2173857T3 (fr)
FI (1) FI904347A0 (fr)
HU (1) HUT57219A (fr)
IE (1) IE903172A1 (fr)
IL (1) IL95564A0 (fr)
MA (1) MA21943A1 (fr)
NO (1) NO903828L (fr)
NZ (1) NZ235130A (fr)
PL (3) PL292044A1 (fr)
ZW (1) ZW13890A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9503717D0 (en) * 1995-02-24 1995-04-12 Smithkline Beecham Plc Novel compounds
JPH11124384A (ja) * 1997-10-17 1999-05-11 Otsuka Chem Co Ltd ３−セフェム化合物の製造法
KR20040035829A (ko) 2001-09-21 2004-04-29 시그마 코팅즈 비.브이. 유기실릴화 카르복실레이트 모노머의 제조방법 및 그것을오염방지 코팅에 사용하는 방법
CN102977123B (zh) * 2012-12-03 2015-04-29 邓世碧 一种头孢类化合物及其药学可接受盐

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16771A (en) * 1978-04-19 1984-02-22 Ciba Geigy Ag Synergistic mixtures of cepsulodin sodium and an aminoglycoside
US4205068A (en) * 1978-05-18 1980-05-27 E. R. Squibb & Sons, Inc. β-Lactamase inhibitor EM4615
JPS60178890A (ja) * 1984-02-23 1985-09-12 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体およびその製造法
KR920004820B1 (ko) * 1984-02-23 1992-06-18 메이지제과 주식회사 새로운 세팔로스포린 유도체의 제조방법
JPS63107989A (ja) * 1986-06-04 1988-05-12 Tanabe Seiyaku Co Ltd セファロスポリン化合物

Also Published As

Publication number Publication date
NO903828L (no) 1991-03-05
DE69033952D1 (de) 2002-05-29
NO903828D0 (no) 1990-09-03
DE69033952T2 (de) 2002-11-28
PL286730A1 (en) 1992-02-24
AU635561B2 (en) 1993-03-25
ES2173857T3 (es) 2002-11-01
HU905701D0 (en) 1991-03-28
ZW13890A1 (en) 1991-10-02
CN1038327C (zh) 1998-05-13
JPH03118381A (ja) 1991-05-20
FI904347A0 (fi) 1990-09-03
EP0416814A2 (fr) 1991-03-13
DK0416814T3 (da) 2002-08-19
CA2024399A1 (fr) 1991-03-05
JP2874987B2 (ja) 1999-03-24
MA21943A1 (fr) 1991-04-01
EP0416814A3 (en) 1992-04-01
CN1050023A (zh) 1991-03-20
IE903172A1 (en) 1991-03-13
EP0416814B1 (fr) 2002-04-24
NZ235130A (en) 1993-05-26
ATE216701T1 (de) 2002-05-15
HUT57219A (en) 1991-11-28
CA2024399C (fr) 2002-02-12
PL292044A1 (en) 1992-07-13
PL292043A1 (en) 1992-07-13
AU6210690A (en) 1991-03-07

Similar Documents

Publication Publication Date Title
CA2053903A1 (fr) Derives n-oxyde heterocycliques de benzo[5,6]cycloheptapyridines; compositions et methodes d'utilisation
AU3256789A (en) Topical preparation for treating otopathy
EP1043327A4 (fr) Derives de phosphonocephem, leur procede de preparation et leur utilisation
ZA895455B (en) Bu-3608 derivatives
IL95564A0 (en) Cephalosporin derivatives
AU6210790A (en) Novel compounds
MY106991A (en) Novel cephalosporin derivatives or compounds
EP0342423A3 (fr) Dérivés d'hétéroaroylhydrazides d'antibiotiques bêta-lactames monocycliques
AU556378B2 (en) N-(2-pyridyl)-2-methyl-4-hydroxy-2h-1,2-benzothiazine 3-carboxamide-1,1-dioxide salt
IL86752A0 (en) Thiophene derivatives and their preparation
EP0345711A3 (fr) Procédé pour la préparation de dérivés de la pyrrolizine
NZ236013A (en) 7-(2-(2-aminothiazolyl(and thiadiazolyl)-2-(hydroxy-imino)acetamido)-3-(4,6-diaminopyrimidinium-2-yl)-thiomethyl-3-cephem-4-carboxylate-0-ether derivatives and pharmaceutical compositions