IL95136A0 - Lhrh analogs - Google Patents

Lhrh analogs

Info

Publication number
IL95136A0
IL95136A0 IL95136A IL9513690A IL95136A0 IL 95136 A0 IL95136 A0 IL 95136A0 IL 95136 A IL95136 A IL 95136A IL 9513690 A IL9513690 A IL 9513690A IL 95136 A0 IL95136 A0 IL 95136A0
Authority
IL
Israel
Prior art keywords
lhrh analogs
lhrh
analogs
Prior art date
Application number
IL95136A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL95136A0 publication Critical patent/IL95136A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL95136A 1989-08-07 1990-07-20 Lhrh analogs IL95136A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39057289A 1989-08-07 1989-08-07
US07/548,512 US5110904A (en) 1989-08-07 1990-07-10 Lhrh analogs

Publications (1)

Publication Number Publication Date
IL95136A0 true IL95136A0 (en) 1991-06-10

Family

ID=27013204

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95136A IL95136A0 (en) 1989-08-07 1990-07-20 Lhrh analogs

Country Status (12)

Country Link
US (1) US5110904A (fr)
EP (1) EP0413209A1 (fr)
JP (1) JPH03101695A (fr)
KR (1) KR0144144B1 (fr)
AU (2) AU6028690A (fr)
CA (1) CA2022444C (fr)
HU (1) HUT54387A (fr)
IE (1) IE902740A1 (fr)
IL (1) IL95136A0 (fr)
NO (1) NO903455L (fr)
PL (1) PL286388A1 (fr)
PT (1) PT94924B (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8713240D0 (en) * 1987-06-05 1987-07-08 Proteus Biotech Ltd Hormones
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
US5300492A (en) * 1988-02-10 1994-04-05 Tap Pharmaceuticals LHRH analogs
US5686410A (en) * 1989-07-20 1997-11-11 Novartis Ag Polypeptide derivatives
DE3936328A1 (de) * 1989-10-27 1991-05-02 Schering Ag Pharmazeutische praeparate
US5352796A (en) * 1989-10-30 1994-10-04 The Salk Institute For Biological Studies Amino acids useful in making GnRH analogs
US5296468A (en) * 1989-10-30 1994-03-22 The Salk Institute For Biological Studies GnRH analogs
ES2062628T3 (es) * 1990-08-04 1994-12-16 Hoechst Ag Antagonistas de gonadoliberina.
US5744450A (en) 1991-03-14 1998-04-28 The Salk Institute For Biological Studies GnRH analogs
DE69214818T2 (de) * 1991-04-25 1997-02-27 Romano S.-Cergue Deghenghi LHRH-Antagonisten
JPH06509075A (ja) * 1991-07-01 1994-10-13 ユニヴァーシティ テクノロジーズ インターナショナル インコーポレイテッド GnRH及び他の生物学的に活性なリガンドの非感度低下性類縁体
US5480969A (en) * 1992-09-15 1996-01-02 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
JPH08504209A (ja) * 1992-12-04 1996-05-07 アボツト・ラボラトリーズ 6位修飾デカペプチドlhrh拮抗薬
TW333456B (en) * 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
UA61046C2 (en) * 1992-12-07 2003-11-17 Takeda Chemical Industries Ltd Sustained-release preparation and method for its manufacture
IL108509A0 (en) * 1993-02-22 1994-05-30 Salk Inst For Biological Studi GnRH antagonist peptides
JP3662926B2 (ja) * 1993-08-06 2005-06-22 タツプ・ホールデイングス・インコーポレイテツド Lhrhのn末端改変類似体
US5413990A (en) * 1993-08-06 1995-05-09 Tap Pharmaceuticals Inc. N-terminus modified analogs of LHRH
US5502035A (en) * 1993-08-06 1996-03-26 Tap Holdings Inc. N-terminus modified analogs of LHRH
EP0668073B1 (fr) * 1994-02-21 1999-04-14 Takeda Chemical Industries, Ltd. Matrice en polyester pour une préparation pharmaceutique à libération prolongée
US5508383A (en) * 1994-03-09 1996-04-16 Tap Holdings Inc. Cyclic peptide LHRH antagonists
US5516759A (en) * 1994-12-08 1996-05-14 Tap Holdings Inc. LHRH antagonists having lactam groups at the N-terminus
US5681928A (en) * 1994-12-16 1997-10-28 The Salk Institute For Biological Studies Betides and methods for screening peptides using same
AU4459196A (en) * 1995-01-23 1996-08-14 Takeda Chemical Industries Ltd. Sustained-release preparation and use
US5843901A (en) 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
DE19544212A1 (de) * 1995-11-28 1997-06-05 Asta Medica Ag Neue LH-RH-Antagonisten mit verbesserter Wirkung
CA2192782C (fr) 1995-12-15 2008-10-14 Nobuyuki Takechi Production de microsphere
US5780435A (en) * 1995-12-15 1998-07-14 Praecis Pharmaceuticals Incorporated Methods for treating prostate cancer with LHRH-R antagonists
US5710247A (en) * 1996-03-19 1998-01-20 Abbott Laboratories Process and intermediates for the synthesis of LHRH antagonists
US5710246A (en) * 1996-03-19 1998-01-20 Abbott Laboratories Process for intermediates for the synthesis of LHRH antagonists
EP0842946A1 (fr) * 1996-11-14 1998-05-20 Laboratoire Theramex S.A. Analogues de LHRH à conformation forcée, leur utilisation et composés pharmaceutiques
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US5821230A (en) * 1997-04-11 1998-10-13 Ferring Bv GnRH antagonist decapeptides
EP0882736A1 (fr) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. Analogues peptidiques du LH-RH, leurs utilisations et compositions pharmaceutiques les contenant
US6191115B1 (en) 1998-08-12 2001-02-20 Abbott Laboratories C-terminus modified heptapeptide LHRH analogs
US6297354B1 (en) 1998-08-12 2001-10-02 Abbott Laboratories Pentapeptide LHRH antagonists
US5981521A (en) * 1998-11-13 1999-11-09 Abbott Laboratories Tetrahydroisoquinoline derivatives as LHRH antagonists
US6455499B1 (en) 1999-02-23 2002-09-24 Indiana University Foundation Methods for treating disorders associated with LHRH activity
DE19911771B4 (de) 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
US6673352B1 (en) * 1999-09-14 2004-01-06 The General Hospital Corporation Use of Mullerian inhibiting substance for treating excess androgen states
CN100500692C (zh) 2000-03-14 2009-06-17 赞塔里斯有限公司 新型lhrh拮抗剂,其制备方法和药物用途
US20030176360A1 (en) 2000-07-05 2003-09-18 Yasutaka Igari Medicinal preparations for treating sex hormone-dependent diseases
US6598784B2 (en) * 2000-12-20 2003-07-29 Meadwestvaco Packaging Syatens, Llc Beverage carton with strap type carrying handle
WO2003000156A1 (fr) 2001-06-22 2003-01-03 Southern Biosystems, Inc. Implants coaxiaux a liberation prolongee d'ordre 0
TWI225416B (en) 2001-06-29 2004-12-21 Takeda Chemical Industries Ltd Sustained-release composition and process for producing the same
US7098305B2 (en) * 2001-09-06 2006-08-29 Ardana Bioscience Limited Sustained release of microcrystalline peptide suspensions
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents
JP2004002321A (ja) * 2002-03-11 2004-01-08 Takeda Chem Ind Ltd 性ホルモン依存性疾患治療剤
AU2003211877A1 (en) * 2002-03-11 2003-09-22 Takeda Chemical Industries, Ltd. Remedies for sex hormone-dependent disease
EP1545604A4 (fr) * 2002-08-23 2006-09-06 Gen Hospital Corp Utilisation d'une substance antimullerienne et d'interferon pour le traitement de tumeurs
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
US20070106271A1 (en) * 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
JP5241507B2 (ja) 2006-11-30 2013-07-17 武田薬品工業株式会社 環状アミン化合物
WO2010142060A1 (fr) * 2009-06-11 2010-12-16 中国人民解放军军事医学科学院毒物药物研究所 Antagoniste de la lhrh à longue durée d'action et faible effet de libération d'histamine
CN104257610A (zh) 2010-04-01 2015-01-07 奇斯药制品公司 用于制备可吸入干粉所用的载体颗粒的方法
US20130177651A1 (en) 2010-09-03 2013-07-11 Pharmaterials Limited Pharmaceutical Composition Suitable for Use in a Dry Powder Inhaler
WO2014010614A1 (fr) 2012-07-12 2014-01-16 武田薬品工業株式会社 Procédé de fabrication de poudre de microcapsule
EP3534974B1 (fr) 2016-11-02 2024-08-21 Board of Regents, The University of Texas System Films dissolubles et leurs procédés d'utilisation

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU497512B2 (en) * 1975-04-15 1978-12-14 Ici Australia Limited Nona and deca-peptides
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor
IT1149971B (it) * 1979-06-11 1986-12-10 Syntex Inc Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante
US4493934A (en) * 1979-10-01 1985-01-15 Merck & Co., Inc. 2(3-Amino-2-oxopyrrolidin-1-yl) acetic acid and n-acylated derivatives thereof
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
US4632979A (en) * 1984-06-18 1986-12-30 Tulane Educational Fund Therapeutic LHRH analogs
US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
US4690916A (en) * 1984-11-13 1987-09-01 Syntex (U.S.A.) Inc. Nona and decapeptide analogs of LHRH useful as LHRH antagonists
US4866160A (en) * 1985-04-09 1989-09-12 The Administrators Of The Tulane Educational Fund Therapeutic decapeptides
US5003011A (en) * 1985-04-09 1991-03-26 The Administrators Of The Tulane Educational Fund Therapeutic decapeptides
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4851385A (en) * 1987-07-15 1989-07-25 Indiana University Foundation LHRH antagonist analogs having low histamine-release activity
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
DE68928278T2 (de) * 1988-02-10 1998-03-12 Tap Pharmaceuticals Inc Lhrh-analog
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists

Also Published As

Publication number Publication date
IE902740A1 (en) 1991-02-27
KR0144144B1 (ko) 1998-07-01
PT94924B (pt) 1997-09-30
CA2022444C (fr) 2002-01-15
EP0413209A1 (fr) 1991-02-20
KR910004661A (ko) 1991-03-29
JPH03101695A (ja) 1991-04-26
AU6028690A (en) 1991-02-07
CA2022444A1 (fr) 1991-02-08
PL286388A1 (en) 1991-05-06
US5110904A (en) 1992-05-05
PT94924A (pt) 1991-05-22
NO903455L (no) 1991-02-08
AU672474B2 (en) 1996-10-03
HUT54387A (en) 1991-02-28
NO903455D0 (no) 1990-08-06
AU5789294A (en) 1994-05-26

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