IL94606A0 - Acylated derivatives of etoposide and pharmaceutical compositions containing them - Google Patents
Acylated derivatives of etoposide and pharmaceutical compositions containing themInfo
- Publication number
- IL94606A0 IL94606A0 IL94606A IL9460690A IL94606A0 IL 94606 A0 IL94606 A0 IL 94606A0 IL 94606 A IL94606 A IL 94606A IL 9460690 A IL9460690 A IL 9460690A IL 94606 A0 IL94606 A0 IL 94606A0
- Authority
- IL
- Israel
- Prior art keywords
- etoposide
- pharmaceutical compositions
- compositions containing
- acylated derivatives
- acylated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/362,555 US5036055A (en) | 1989-06-07 | 1989-06-07 | Acylated derivatives of etoposide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL94606A0 true IL94606A0 (en) | 1991-04-15 |
Family
ID=23426565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL94606A IL94606A0 (en) | 1989-06-07 | 1990-06-04 | Acylated derivatives of etoposide and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5036055A (xx) |
| EP (1) | EP0401800A3 (xx) |
| JP (1) | JPH0324097A (xx) |
| KR (1) | KR910000778A (xx) |
| CN (1) | CN1024197C (xx) |
| AU (1) | AU637104B2 (xx) |
| CA (1) | CA2018067A1 (xx) |
| CZ (1) | CZ283890A3 (xx) |
| DD (1) | DD294947A5 (xx) |
| FI (1) | FI902767A0 (xx) |
| HU (1) | HU206221B (xx) |
| IL (1) | IL94606A0 (xx) |
| NO (1) | NO173239C (xx) |
| NZ (1) | NZ233900A (xx) |
| PT (1) | PT94281A (xx) |
| YU (1) | YU110690A (xx) |
| ZA (1) | ZA904366B (xx) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5191071A (en) * | 1987-08-21 | 1993-03-02 | Novo Nordisk A/S | Monoesters of glycosides and a process for enzymatic preparation thereof |
| US6610299B1 (en) | 1989-10-19 | 2003-08-26 | Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
| US7241595B2 (en) * | 1989-10-20 | 2007-07-10 | Sanofi-Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
| US6475486B1 (en) | 1990-10-18 | 2002-11-05 | Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
| US5034380A (en) * | 1989-11-20 | 1991-07-23 | Bristol-Myers Squibb Company | Alkoxymethylidene epipodophyllotoxin glucosides |
| CN1025918C (zh) * | 1990-06-07 | 1994-09-14 | 国家医药管理局上海医药工业研究院 | 抗肿瘤药表鬼臼毒吡喃糖甙的合成新工艺 |
| TW260671B (xx) * | 1991-04-29 | 1995-10-21 | Bristol Myers Squibb Co | |
| IT1250692B (it) * | 1991-07-23 | 1995-04-21 | Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi. | |
| JP3061476B2 (ja) * | 1992-04-24 | 2000-07-10 | 日本化薬株式会社 | エトポシド燐酸エステルの製造法 |
| US5459248A (en) * | 1993-11-04 | 1995-10-17 | Bristol-Myers Squibb Company | Process of preparing etoposide phosphate and etoposide |
| EP0778282B1 (en) * | 1995-12-04 | 2003-04-09 | Nippon Kayaku Kabushiki Kaisha | Process for producing etoposide |
| AU728986B2 (en) * | 1997-06-02 | 2001-01-25 | Bristol-Myers Squibb Company | Process for preparing etoposide |
| CA2385528C (en) | 1999-10-01 | 2013-12-10 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US8240508B2 (en) | 2008-12-29 | 2012-08-14 | Gojo Industries, Inc. | Low cost radio frequency identification (RFID) dispensing systems |
| CN105246899A (zh) * | 2013-01-14 | 2016-01-13 | 艾德瓦诺米科斯公司 | 作为抗癌药物的gem-二氟化c-糖苷化合物 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6613143A (xx) * | 1965-09-21 | 1967-03-22 | ||
| CH507934A (de) * | 1965-12-14 | 1971-05-31 | Sandoz Ag | Verfahren zur Herstellung eines neuen Glucosids |
| FR1518706A (fr) * | 1965-12-14 | 1968-03-29 | Sandoz Sa | Glucosides dérivant de composés apparentés à la podophyllotoxine et leur préparation |
| CH514578A (de) * | 1968-02-27 | 1971-10-31 | Sandoz Ag | Verfahren zur Herstellung von Glucosiden |
| JPS58219196A (ja) * | 1982-06-15 | 1983-12-20 | Nippon Kayaku Co Ltd | ４′−デメチル−エピポドフイロトキシン−β−Ｄ−エチリデングルコシドの製造法 |
| JPS58225096A (ja) * | 1982-06-25 | 1983-12-27 | Nippon Kayaku Co Ltd | ４′−デメチル−エピポドフイロトキシン−β−Ｄ−エチリデングルコシドの新規製造法 |
| DE3374317D1 (en) * | 1982-11-26 | 1987-12-10 | Nippon Kayaku Kk | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| US4567253A (en) * | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
| JPS60246393A (ja) * | 1984-05-22 | 1985-12-06 | Nippon Kayaku Co Ltd | エトポシドの新規製造法 |
| US4609644A (en) * | 1984-06-15 | 1986-09-02 | St. Jude Children's Research Hospital | Epipodophyllotoxinquinone glucoside derivatives, method of production and use |
| JPS61134396A (ja) * | 1984-12-06 | 1986-06-21 | Nippon Kayaku Co Ltd | エトポシドの新規製造法 |
| JPS61227590A (ja) * | 1985-04-02 | 1986-10-09 | Microbial Chem Res Found | 新規４′−デメチル−４−エピポドフイロトキシン誘導体 |
| IL77334A (en) * | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
| JPS63150293A (ja) * | 1986-12-12 | 1988-06-22 | Nippon Kayaku Co Ltd | エトポシド水溶性誘導体 |
| US4916217A (en) * | 1987-01-08 | 1990-04-10 | Bristol-Myers Company | Phosphorus containing derivatives of epipodophyllotoxin |
| JPS63192793A (ja) * | 1987-02-06 | 1988-08-10 | Nippon Kayaku Co Ltd | ４′−デメチル−エピポドフイロトキシン誘導体の新規エステル |
| US4853467A (en) * | 1987-05-19 | 1989-08-01 | Bristol-Myers Company | Nitrogen containing derivatives of epipodophyllotoxin glucosides |
| US4874851A (en) * | 1987-07-01 | 1989-10-17 | Bristol-Meyers Company | 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives |
| US4904768A (en) * | 1987-08-04 | 1990-02-27 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-phosphate derivatives |
| US4868291A (en) * | 1987-08-20 | 1989-09-19 | Bristol-Myers Company | 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use |
| US4888419A (en) * | 1987-08-31 | 1989-12-19 | Bristol-Myers Company | 3'-demethoxyepipodophyllotoxin glucoside derivatives |
| ZA886810B (en) * | 1987-12-18 | 1989-08-30 | Bristol Myers Co | Epipodophyllotoxin glucoside 4'-acyl derivatives |
| US4912204A (en) * | 1988-09-06 | 1990-03-27 | Bristol-Myers Company | Fluoro-substituted epipodophyllotoxin glucosides |
| US5066645A (en) * | 1989-09-01 | 1991-11-19 | Bristol-Myers Company | Epipodophyllotoxin altroside derivatives |
-
1989
- 1989-06-07 US US07/362,555 patent/US5036055A/en not_active Expired - Fee Related
-
1990
- 1990-06-01 NZ NZ233900A patent/NZ233900A/en unknown
- 1990-06-01 CA CA002018067A patent/CA2018067A1/en not_active Abandoned
- 1990-06-04 IL IL94606A patent/IL94606A0/xx unknown
- 1990-06-04 FI FI902767A patent/FI902767A0/fi not_active Application Discontinuation
- 1990-06-04 CN CN90104190A patent/CN1024197C/zh not_active Expired - Fee Related
- 1990-06-05 KR KR1019900008275A patent/KR910000778A/ko not_active Application Discontinuation
- 1990-06-06 ZA ZA904366A patent/ZA904366B/xx unknown
- 1990-06-06 DD DD90341368A patent/DD294947A5/de not_active IP Right Cessation
- 1990-06-06 PT PT94281A patent/PT94281A/pt not_active Application Discontinuation
- 1990-06-06 YU YU01106/90A patent/YU110690A/xx unknown
- 1990-06-06 AU AU56828/90A patent/AU637104B2/en not_active Ceased
- 1990-06-06 NO NO902495A patent/NO173239C/no unknown
- 1990-06-06 EP EP19900110729 patent/EP0401800A3/en not_active Ceased
- 1990-06-07 JP JP2147535A patent/JPH0324097A/ja active Pending
- 1990-06-07 HU HU903517A patent/HU206221B/hu not_active IP Right Cessation
- 1990-06-07 CZ CS902838A patent/CZ283890A3/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR910000778A (ko) | 1991-01-30 |
| HU206221B (en) | 1992-09-28 |
| HUT54174A (en) | 1991-01-28 |
| NZ233900A (en) | 1992-02-25 |
| AU5682890A (en) | 1990-12-13 |
| CA2018067A1 (en) | 1990-12-07 |
| NO902495L (no) | 1990-12-10 |
| US5036055A (en) | 1991-07-30 |
| EP0401800A2 (en) | 1990-12-12 |
| JPH0324097A (ja) | 1991-02-01 |
| CN1024197C (zh) | 1994-04-13 |
| ZA904366B (en) | 1991-05-29 |
| AU637104B2 (en) | 1993-05-20 |
| YU110690A (en) | 1992-05-28 |
| NO173239C (no) | 1993-11-17 |
| CZ283890A3 (en) | 1995-02-15 |
| PT94281A (pt) | 1991-02-08 |
| EP0401800A3 (en) | 1991-04-10 |
| NO173239B (no) | 1993-08-09 |
| CN1047869A (zh) | 1990-12-19 |
| HU903517D0 (en) | 1990-10-28 |
| FI902767A0 (fi) | 1990-06-04 |
| NO902495D0 (no) | 1990-06-06 |
| DD294947A5 (de) | 1991-10-17 |
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