IL94582A - A topical preparation containing decomposed polymers of deoxyribonucleic acids for the development of malignant malformations in the skin surface of the face and in the number of Io - Google Patents
A topical preparation containing decomposed polymers of deoxyribonucleic acids for the development of malignant malformations in the skin surface of the face and in the number of IoInfo
- Publication number
- IL94582A IL94582A IL9458290A IL9458290A IL94582A IL 94582 A IL94582 A IL 94582A IL 9458290 A IL9458290 A IL 9458290A IL 9458290 A IL9458290 A IL 9458290A IL 94582 A IL94582 A IL 94582A
- Authority
- IL
- Israel
- Prior art keywords
- topical use
- deoxyribonucleic acids
- depolymerized
- compositions
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 38
- 230000000699 topical effect Effects 0.000 title claims abstract description 29
- 108020004414 DNA Proteins 0.000 title claims abstract description 27
- 102000053602 DNA Human genes 0.000 title claims abstract description 25
- 230000007547 defect Effects 0.000 title claims description 7
- 210000003491 skin Anatomy 0.000 title description 10
- 210000002615 epidermis Anatomy 0.000 title description 7
- 239000004480 active ingredient Substances 0.000 claims abstract description 10
- 210000003141 lower extremity Anatomy 0.000 claims abstract description 6
- 238000002360 preparation method Methods 0.000 claims description 11
- 102000039446 nucleic acids Human genes 0.000 claims description 9
- 108020004707 nucleic acids Proteins 0.000 claims description 9
- 150000007523 nucleic acids Chemical class 0.000 claims description 9
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims description 7
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 claims description 7
- 239000006071 cream Substances 0.000 claims description 6
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 229930024421 Adenine Natural products 0.000 claims description 4
- 229960000643 adenine Drugs 0.000 claims description 4
- 229940104302 cytosine Drugs 0.000 claims description 4
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 3
- 239000006210 lotion Substances 0.000 claims description 3
- 239000002674 ointment Substances 0.000 claims description 3
- 229940113082 thymine Drugs 0.000 claims description 3
- 208000035484 Cellulite Diseases 0.000 claims description 2
- 206010049752 Peau d'orange Diseases 0.000 claims description 2
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052757 nitrogen Inorganic materials 0.000 claims description 2
- 239000000499 gel Substances 0.000 claims 2
- ASJSAQIRZKANQN-CRCLSJGQSA-N 2-deoxy-D-ribose Chemical compound OC[C@@H](O)[C@@H](O)CC=O ASJSAQIRZKANQN-CRCLSJGQSA-N 0.000 claims 1
- 208000032912 Local swelling Diseases 0.000 claims 1
- 230000036232 cellulite Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 206010030113 Oedema Diseases 0.000 abstract description 7
- 238000009472 formulation Methods 0.000 description 19
- 238000000034 method Methods 0.000 description 12
- 241001465754 Metazoa Species 0.000 description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 235000005911 diet Nutrition 0.000 description 9
- 230000037213 diet Effects 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 6
- 239000002304 perfume Substances 0.000 description 6
- 210000003414 extremity Anatomy 0.000 description 5
- 150000002500 ions Chemical class 0.000 description 5
- 239000003755 preservative agent Substances 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 210000003423 ankle Anatomy 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 3
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 3
- 206010007191 Capillary fragility Diseases 0.000 description 3
- UOACKFBJUYNSLK-XRKIENNPSA-N Estradiol Cypionate Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H](C4=CC=C(O)C=C4CC3)CC[C@@]21C)C(=O)CCC1CCCC1 UOACKFBJUYNSLK-XRKIENNPSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 241000700159 Rattus Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- 238000000692 Student's t-test Methods 0.000 description 2
- 206010043189 Telangiectasia Diseases 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000021590 normal diet Nutrition 0.000 description 2
- 229940068196 placebo Drugs 0.000 description 2
- 239000000902 placebo Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 208000009056 telangiectasis Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- 102100024133 Coiled-coil domain-containing protein 50 Human genes 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 244000257039 Duranta repens Species 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010056474 Erythrosis Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 101000910772 Homo sapiens Coiled-coil domain-containing protein 50 Proteins 0.000 description 1
- 241000575946 Ione Species 0.000 description 1
- LTXREWYXXSTFRX-QGZVFWFLSA-N Linagliptin Chemical compound N=1C=2N(C)C(=O)N(CC=3N=C4C=CC=CC4=C(C)N=3)C(=O)C=2N(CC#CC)C=1N1CCC[C@@H](N)C1 LTXREWYXXSTFRX-QGZVFWFLSA-N 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920001214 Polysorbate 60 Polymers 0.000 description 1
- 208000036367 Sensation of heaviness Diseases 0.000 description 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- WTHXTWHYLIZJBH-UHFFFAOYSA-N acetic acid;azane Chemical compound N.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O WTHXTWHYLIZJBH-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- UJRRDDHEMZLWFI-UHFFFAOYSA-N aminitrozole Chemical compound CC(=O)NC1=NC=C([N+]([O-])=O)S1 UJRRDDHEMZLWFI-UHFFFAOYSA-N 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- 235000019445 benzyl alcohol Nutrition 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 208000037516 chromosome inversion disease Diseases 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229940043351 ethyl-p-hydroxybenzoate Drugs 0.000 description 1
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 229940075507 glyceryl monostearate Drugs 0.000 description 1
- 229940100242 glycol stearate Drugs 0.000 description 1
- 244000144993 groups of animals Species 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000004407 iron oxides and hydroxides Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- CIBMHJPPKCXONB-UHFFFAOYSA-N propane-2,2-diol Chemical compound CC(C)(O)O CIBMHJPPKCXONB-UHFFFAOYSA-N 0.000 description 1
- 229910001426 radium ion Inorganic materials 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 1
- AYRVGWHSXIMRAB-UHFFFAOYSA-M sodium acetate trihydrate Chemical compound O.O.O.[Na+].CC([O-])=O AYRVGWHSXIMRAB-UHFFFAOYSA-M 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 210000000216 zygoma Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8921650A IT1232318B (it) | 1989-09-07 | 1989-09-07 | Composizioni ad uso topico contenenti acidi nucleici depolimerizzati per la cosmesi della pelle e del corpo. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL94582A0 IL94582A0 (en) | 1991-04-15 |
| IL94582A true IL94582A (en) | 1994-10-07 |
Family
ID=11184847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9458290A IL94582A (en) | 1989-09-07 | 1990-06-01 | A topical preparation containing decomposed polymers of deoxyribonucleic acids for the development of malignant malformations in the skin surface of the face and in the number of Io |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5126331A (it) |
| EP (1) | EP0416677B1 (it) |
| JP (1) | JPH0399017A (it) |
| KR (1) | KR970009581B1 (it) |
| AT (1) | ATE98868T1 (it) |
| AU (1) | AU631441B2 (it) |
| BE (1) | BE1003350A3 (it) |
| CH (1) | CH682804A5 (it) |
| DE (1) | DE69005398T2 (it) |
| DK (1) | DK0416677T3 (it) |
| ES (1) | ES2026754A6 (it) |
| FR (1) | FR2651434B1 (it) |
| GR (1) | GR1000637B (it) |
| IL (1) | IL94582A (it) |
| IT (1) | IT1232318B (it) |
| LU (1) | LU87799A1 (it) |
| NZ (1) | NZ233987A (it) |
| PT (1) | PT95211B (it) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1252174B (it) * | 1991-12-09 | 1995-06-05 | Crinos Industria Farmaco | Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento |
| AU6714094A (en) * | 1993-04-28 | 1994-11-21 | Ribozyme Pharmaceuticals, Inc. | Ocular delivery of nucleic acid |
| US5470577A (en) * | 1993-07-07 | 1995-11-28 | Trustees Of Boston University | Stimulation of tanning by DNA fragments or single-stranded DNA |
| JP2688116B2 (ja) * | 1993-07-29 | 1997-12-08 | ロレアル | メークアップ用組成物 |
| IT1270602B (it) * | 1994-07-12 | 1997-05-07 | Indena Spa | Formulazioni a base di esculoside e loro uso in campo farmaceutico e cosmetico |
| US5858339A (en) * | 1995-03-29 | 1999-01-12 | L'oreal | Method for making up the eyes using deoxyribonucleic acid |
| DE19545107A1 (de) * | 1995-12-04 | 1997-06-05 | Beiersdorf Ag | Verwendung eines wirksamen Gehaltes an Adenosin in kosmetischen oder dermatologischen Zubereitungen |
| USRE37380E1 (en) * | 1996-07-12 | 2001-09-18 | Bertrand Piot | Method for making up the eyes using deoxyribonucleic acid |
| DE19815090A1 (de) * | 1998-04-06 | 1999-10-14 | Henkel Kgaa | Kosmetische Mittel |
| US6946144B1 (en) * | 1998-07-08 | 2005-09-20 | Oryxe | Transdermal delivery system |
| JP2002541822A (ja) * | 1999-04-14 | 2002-12-10 | エム ユー エス シー ファンデーション フォー リサーチ ディベロップメント | 組織特異的および病原体特異的毒性物質ならびにリボザイム |
| EP1539245A2 (en) * | 2002-06-26 | 2005-06-15 | The Penn State Research Foundation | Methods and materials for treating human papillomavirus infections |
| JP5025253B2 (ja) * | 2006-03-31 | 2012-09-12 | 日生バイオ株式会社 | 基礎化粧品用配合剤及び基礎化粧品 |
| US9358037B2 (en) | 2007-06-26 | 2016-06-07 | Roxwood Medical, Inc. | Method and apparatus for centering a microcatheter within a vasculature |
| JP6403686B2 (ja) | 2012-12-31 | 2018-10-10 | ジェイアールエックス バイオテクノロジー，インコーポレイテッド | 液体局所用医薬ナノエマルジョン製剤 |
| HK1256695A1 (zh) | 2015-09-17 | 2019-10-04 | Jrx Biotechnology, Inc. | 改善皮肤的水合作用或润湿作用的方法 |
| GB201703656D0 (en) * | 2017-03-07 | 2017-04-19 | Univ Sheffield | Wound healing medicament |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1361925A (fr) * | 1963-02-27 | 1964-05-29 | Nouvelle composition à usage capillaire | |
| FR1603826A (en) * | 1968-12-09 | 1971-06-07 | Dna-and rna-contg cosmetic prods | |
| DE2509531A1 (de) * | 1975-03-05 | 1976-09-16 | Thomae Gmbh Dr K | Antivirales mittel |
| JPS59134706A (ja) * | 1983-01-19 | 1984-08-02 | Kobayashi Kooc:Kk | 化粧料 |
| US4557934A (en) * | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US4885157A (en) * | 1987-02-13 | 1989-12-05 | Fiaschetti Mary G | Dermal cosmetic composition and applications therefor |
| IT1222701B (it) * | 1987-09-23 | 1990-09-12 | Crinos Industria Farmaco | Composizione ad uso topico avente attivita' tricogena,antiforfora ed antiseborroica |
| FR2609393A1 (fr) * | 1988-02-23 | 1988-07-15 | Serobiologiques Lab Sa | Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques comprenant une substance azotee, notamment aminoacides, oligo- ou polypeptides, proteines, et leurs derives, et composition pharmaceutique ou cosmetique ainsi preparee. |
-
1989
- 1989-09-07 IT IT8921650A patent/IT1232318B/it active
-
1990
- 1990-06-01 IL IL9458290A patent/IL94582A/en not_active IP Right Cessation
- 1990-06-08 NZ NZ233987A patent/NZ233987A/en unknown
- 1990-07-20 AU AU59169/90A patent/AU631441B2/en not_active Ceased
- 1990-08-10 EP EP90202171A patent/EP0416677B1/en not_active Expired - Lifetime
- 1990-08-10 AT AT90202171T patent/ATE98868T1/de not_active IP Right Cessation
- 1990-08-10 DE DE90202171T patent/DE69005398T2/de not_active Expired - Fee Related
- 1990-08-10 DK DK90202171.6T patent/DK0416677T3/da active
- 1990-08-16 US US07/568,125 patent/US5126331A/en not_active Expired - Fee Related
- 1990-08-16 GR GR900100612A patent/GR1000637B/el unknown
- 1990-09-03 JP JP2230744A patent/JPH0399017A/ja active Pending
- 1990-09-05 PT PT95211A patent/PT95211B/pt not_active IP Right Cessation
- 1990-09-05 CH CH2881/90A patent/CH682804A5/it not_active IP Right Cessation
- 1990-09-06 LU LU87799A patent/LU87799A1/fr unknown
- 1990-09-07 KR KR90014173A patent/KR970009581B1/ko not_active Expired - Fee Related
- 1990-09-07 ES ES9002332A patent/ES2026754A6/es not_active Expired - Fee Related
- 1990-09-07 BE BE9000864A patent/BE1003350A3/fr not_active IP Right Cessation
- 1990-09-07 FR FR909011104A patent/FR2651434B1/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GR900100612A (en) | 1992-01-20 |
| DE69005398D1 (de) | 1994-02-03 |
| FR2651434B1 (fr) | 1993-08-06 |
| DE69005398T2 (de) | 1994-04-14 |
| GR1000637B (el) | 1992-09-11 |
| CH682804A5 (it) | 1993-11-30 |
| IT8921650A0 (it) | 1989-09-07 |
| IL94582A0 (en) | 1991-04-15 |
| ES2026754A6 (es) | 1992-05-01 |
| KR970009581B1 (en) | 1997-06-14 |
| EP0416677A1 (en) | 1991-03-13 |
| LU87799A1 (fr) | 1991-02-18 |
| PT95211A (pt) | 1991-05-22 |
| KR910005877A (ko) | 1991-04-27 |
| IT1232318B (it) | 1992-01-28 |
| DK0416677T3 (da) | 1994-01-31 |
| AU631441B2 (en) | 1992-11-26 |
| AU5916990A (en) | 1991-03-14 |
| NZ233987A (en) | 1992-10-28 |
| US5126331A (en) | 1992-06-30 |
| FR2651434A1 (fr) | 1991-03-08 |
| PT95211B (pt) | 1997-06-30 |
| EP0416677B1 (en) | 1993-12-22 |
| JPH0399017A (ja) | 1991-04-24 |
| BE1003350A3 (fr) | 1992-03-03 |
| ATE98868T1 (de) | 1994-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void |