IL94566A0 - Monoclonal antibodies for inducing tolerance to an antigen - Google Patents

Monoclonal antibodies for inducing tolerance to an antigen

Info

Publication number
IL94566A0
IL94566A0 IL94566A IL9456690A IL94566A0 IL 94566 A0 IL94566 A0 IL 94566A0 IL 94566 A IL94566 A IL 94566A IL 9456690 A IL9456690 A IL 9456690A IL 94566 A0 IL94566 A0 IL 94566A0
Authority
IL
Israel
Prior art keywords
antigen
monoclonal antibodies
depleting
inducing tolerance
monoclonal antibody
Prior art date
Application number
IL94566A
Other languages
English (en)
Original Assignee
Cobbold Stephen P
Waldmann Herman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobbold Stephen P, Waldmann Herman filed Critical Cobbold Stephen P
Publication of IL94566A0 publication Critical patent/IL94566A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2815—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL94566A 1989-05-31 1990-05-31 Monoclonal antibodies for inducing tolerance to an antigen IL94566A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898912497A GB8912497D0 (en) 1989-05-31 1989-05-31 Monoclonal antibodies

Publications (1)

Publication Number Publication Date
IL94566A0 true IL94566A0 (en) 1991-03-10

Family

ID=10657649

Family Applications (1)

Application Number Title Priority Date Filing Date
IL94566A IL94566A0 (en) 1989-05-31 1990-05-31 Monoclonal antibodies for inducing tolerance to an antigen

Country Status (19)

Country Link
EP (1) EP0474691B1 (de)
JP (1) JP2763197B2 (de)
KR (1) KR0183029B1 (de)
AT (1) ATE145246T1 (de)
AU (1) AU657255B2 (de)
CA (1) CA2055615C (de)
DD (1) DD296843A5 (de)
DE (1) DE69029134T2 (de)
DK (1) DK0474691T3 (de)
ES (1) ES2096588T3 (de)
GB (1) GB8912497D0 (de)
HU (1) HUT61341A (de)
IE (1) IE80735B1 (de)
IL (1) IL94566A0 (de)
MY (1) MY135673A (de)
NZ (1) NZ233889A (de)
PT (1) PT94214B (de)
WO (1) WO1990015152A1 (de)
ZA (1) ZA904174B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9100741D0 (en) * 1991-01-14 1991-02-27 Univ London Treatment of disease
US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
AU687755B2 (en) * 1992-08-21 1998-03-05 Genentech Inc. Method for treating an LFA-1-mediated disorder
US6270766B1 (en) 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
DE69627665T2 (de) * 1995-05-18 2004-02-19 Ortho-Mcneil Pharmaceutical, Inc. Induktion von immunologischer toleranz unter verwendung von nicht-zellmengeverringernden anti-cd4-antikoepern
US6984720B1 (en) 1999-08-24 2006-01-10 Medarex, Inc. Human CTLA-4 antibodies
US7011952B2 (en) 2000-02-22 2006-03-14 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
DE60136272D1 (de) 2000-04-29 2008-12-04 Univ Iowa Res Found Diagnostika und therapeutika für makula degeneration erkrankungen
ATE490783T1 (de) * 2001-06-14 2010-12-15 Isis Innovation Nicht-depletierender antikörper trx-1 gegen cd4 und dessen verwendungen
US7541443B2 (en) * 2001-06-14 2009-06-02 Tolerrx, Inc. Anti-CD4 antibodies
EP1460088A1 (de) 2003-03-21 2004-09-22 Biotest AG Humanisierter Antikörper gegen CD4 mit immunsuppressiven Merkmalen
GB0314461D0 (en) * 2003-06-20 2003-07-23 Isis Innovation Suppression of transplant rejection
JP2008503593A (ja) * 2004-06-22 2008-02-07 トーラーレックス， インク． 霊長類で寛容を誘導するための抗ｃｄ４抗体で最適化された投薬
KR20100135808A (ko) 2008-03-13 2010-12-27 바이오테스트 아게 질병 치료제
KR20100135257A (ko) 2008-03-13 2010-12-24 바이오테스트 아게 질병 치료제
AU2009235622C9 (en) 2008-03-13 2015-07-02 Biotest Ag Agent for treating disease
CN102112491A (zh) * 2008-06-06 2011-06-29 贝勒研究院 抗-cd8抗体阻断细胞毒素效应物的引发并导致调节性cd8+t细胞的产生
WO2010009129A2 (en) * 2008-07-15 2010-01-21 Genentech, Inc. Methods of treating autoimmune diseases using cd4 antibodies
GB0920944D0 (en) 2009-11-30 2010-01-13 Biotest Ag Agents for treating disease
WO2024112867A1 (en) 2022-11-23 2024-05-30 University Of Georgia Research Foundation, Inc. Compositions and methods of use thereof for increasing immune responses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608068D0 (en) * 1986-04-02 1986-05-08 Cobbold S P Monoclonal antibodies

Also Published As

Publication number Publication date
ATE145246T1 (de) 1996-11-15
WO1990015152A1 (en) 1990-12-13
ZA904174B (en) 1992-02-26
HU905134D0 (en) 1992-02-28
NZ233889A (en) 1997-06-24
PT94214B (pt) 1997-03-31
MY135673A (en) 2008-06-30
AU657255B2 (en) 1995-03-09
GB8912497D0 (en) 1989-07-19
DK0474691T3 (da) 1996-12-02
DE69029134T2 (de) 1997-03-06
DE69029134D1 (de) 1996-12-19
IE80735B1 (en) 1998-12-30
JP2763197B2 (ja) 1998-06-11
EP0474691B1 (de) 1996-11-13
CA2055615C (en) 2001-07-17
HUT61341A (en) 1992-12-28
DD296843A5 (de) 1991-12-19
JPH04505919A (ja) 1992-10-15
CA2055615A1 (en) 1990-12-13
PT94214A (pt) 1991-02-08
ES2096588T3 (es) 1997-03-16
KR0183029B1 (ko) 1999-04-01
IE901949L (en) 1990-11-30
AU5725890A (en) 1991-01-07
EP0474691A1 (de) 1992-03-18

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