IL93051A0 - ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them - Google Patents
((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL93051A0 IL93051A0 IL93051A IL9305190A IL93051A0 IL 93051 A0 IL93051 A0 IL 93051A0 IL 93051 A IL93051 A IL 93051A IL 9305190 A IL9305190 A IL 9305190A IL 93051 A0 IL93051 A0 IL 93051A0
- Authority
- IL
- Israel
- Prior art keywords
- lower alkyl
- aryl
- hydrogen
- cyclohexaneacetamides
- pyrrolidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29772689A | 1989-01-17 | 1989-01-17 | |
| US37764389A | 1989-07-10 | 1989-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL93051A0 true IL93051A0 (en) | 1990-11-05 |
Family
ID=26970288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL93051A IL93051A0 (en) | 1989-01-17 | 1990-01-15 | ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0381959B1 (ja) |
| JP (1) | JPH02229154A (ja) |
| KR (1) | KR900011759A (ja) |
| AT (1) | ATE122037T1 (ja) |
| AU (1) | AU625157B2 (ja) |
| CA (1) | CA2007732A1 (ja) |
| DE (1) | DE69019007T2 (ja) |
| DK (1) | DK0381959T3 (ja) |
| ES (1) | ES2071685T3 (ja) |
| FI (1) | FI900231A0 (ja) |
| HU (1) | HUT53607A (ja) |
| IL (1) | IL93051A0 (ja) |
| MC (1) | MC2081A1 (ja) |
| NO (1) | NO174386C (ja) |
| NZ (1) | NZ232112A (ja) |
| PT (1) | PT92874A (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100395779B1 (ko) * | 2001-05-25 | 2003-08-21 | 한국화학연구원 | 임의적으로 베타-위치가 치환된 알파-아릴알킬기의 제거를통해 3급 아미드 화합물로부터 2급 아미드 화합물을제조하는 방법 |
| CN102227217A (zh) | 2008-10-16 | 2011-10-26 | 约翰斯.霍普金斯大学 | 改善认知功能的方法和组合物 |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
| DK2968220T3 (da) | 2013-03-15 | 2021-06-14 | Agenebio Inc | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
| EP2968237A4 (en) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION |
| BR112017025031B1 (pt) | 2015-05-22 | 2023-03-21 | Agenebio, Inc | Composições farmacêuticas de liberação prolongada de levetiracetam |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1045043B (it) * | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
| DE3336024A1 (de) * | 1983-10-04 | 1985-04-18 | Boehringer Ingelheim KG, 6507 Ingelheim | 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
| US4668687A (en) * | 1984-07-23 | 1987-05-26 | Bristol-Myers Company | Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones |
| IT1190378B (it) * | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| IT1224168B (it) * | 1986-08-01 | 1990-09-26 | Finanziaria R F Spa Ora Finanz | Derivati del pirrolidin-2-one ad attivita' nootropa |
-
1990
- 1990-01-15 IL IL93051A patent/IL93051A0/xx not_active IP Right Cessation
- 1990-01-15 CA CA002007732A patent/CA2007732A1/en not_active Abandoned
- 1990-01-15 AU AU47988/90A patent/AU625157B2/en not_active Ceased
- 1990-01-15 NZ NZ232112A patent/NZ232112A/en unknown
- 1990-01-15 HU HU90127A patent/HUT53607A/hu unknown
- 1990-01-16 FI FI900231A patent/FI900231A0/fi not_active Application Discontinuation
- 1990-01-16 JP JP2007018A patent/JPH02229154A/ja active Pending
- 1990-01-16 PT PT92874A patent/PT92874A/pt not_active Application Discontinuation
- 1990-01-16 NO NO900234A patent/NO174386C/no unknown
- 1990-01-16 MC MC902092A patent/MC2081A1/xx unknown
- 1990-01-16 KR KR1019900000452A patent/KR900011759A/ko not_active Application Discontinuation
- 1990-01-17 DE DE69019007T patent/DE69019007T2/de not_active Expired - Fee Related
- 1990-01-17 DK DK90100935.7T patent/DK0381959T3/da active
- 1990-01-17 ES ES90100935T patent/ES2071685T3/es not_active Expired - Lifetime
- 1990-01-17 AT AT90100935T patent/ATE122037T1/de not_active IP Right Cessation
- 1990-01-17 EP EP90100935A patent/EP0381959B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HU900127D0 (en) | 1990-03-28 |
| JPH02229154A (ja) | 1990-09-11 |
| ATE122037T1 (de) | 1995-05-15 |
| AU625157B2 (en) | 1992-07-02 |
| DE69019007D1 (de) | 1995-06-08 |
| HUT53607A (en) | 1990-11-28 |
| DE69019007T2 (de) | 1995-09-14 |
| NO174386B (no) | 1994-01-17 |
| CA2007732A1 (en) | 1990-07-17 |
| FI900231A0 (fi) | 1990-01-16 |
| NO900234D0 (no) | 1990-01-16 |
| PT92874A (pt) | 1990-07-31 |
| AU4798890A (en) | 1990-07-26 |
| KR900011759A (ko) | 1990-08-02 |
| DK0381959T3 (da) | 1995-09-04 |
| EP0381959B1 (en) | 1995-05-03 |
| MC2081A1 (fr) | 1991-01-07 |
| EP0381959A1 (en) | 1990-08-16 |
| NO174386C (no) | 1994-04-27 |
| ES2071685T3 (es) | 1995-07-01 |
| NZ232112A (en) | 1992-07-28 |
| NO900234L (no) | 1990-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |