MC2081A1 - Procede de preparation cyclohexaneacetamides - Google Patents

Procede de preparation cyclohexaneacetamides

Info

Publication number
MC2081A1
MC2081A1 MC902092A MC2092A MC2081A1 MC 2081 A1 MC2081 A1 MC 2081A1 MC 902092 A MC902092 A MC 902092A MC 2092 A MC2092 A MC 2092A MC 2081 A1 MC2081 A1 MC 2081A1
Authority
MC
Monaco
Prior art keywords
lower alkyl
aryl
hydrogen
chem
cyclohexaneacetamides
Prior art date
Application number
MC902092A
Other languages
English (en)
French (fr)
Inventor
Lee Olson Gary
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2081A1 publication Critical patent/MC2081A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC902092A 1989-01-17 1990-01-16 Procede de preparation cyclohexaneacetamides MC2081A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29772689A 1989-01-17 1989-01-17
US37764389A 1989-07-10 1989-07-10

Publications (1)

Publication Number Publication Date
MC2081A1 true MC2081A1 (fr) 1991-01-07

Family

ID=26970288

Family Applications (1)

Application Number Title Priority Date Filing Date
MC902092A MC2081A1 (fr) 1989-01-17 1990-01-16 Procede de preparation cyclohexaneacetamides

Country Status (16)

Country Link
EP (1) EP0381959B1 (xx)
JP (1) JPH02229154A (xx)
KR (1) KR900011759A (xx)
AT (1) ATE122037T1 (xx)
AU (1) AU625157B2 (xx)
CA (1) CA2007732A1 (xx)
DE (1) DE69019007T2 (xx)
DK (1) DK0381959T3 (xx)
ES (1) ES2071685T3 (xx)
FI (1) FI900231A0 (xx)
HU (1) HUT53607A (xx)
IL (1) IL93051A0 (xx)
MC (1) MC2081A1 (xx)
NO (1) NO174386C (xx)
NZ (1) NZ232112A (xx)
PT (1) PT92874A (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100395779B1 (ko) * 2001-05-25 2003-08-21 한국화학연구원 임의적으로 베타-위치가 치환된 알파-아릴알킬기의 제거를통해 3급 아미드 화합물로부터 2급 아미드 화합물을제조하는 방법
JP5917148B2 (ja) 2008-10-16 2016-05-11 ザ ジョーンズ ホプキンズ ユニバーシティThe Johns Hopkins University 認知機能を改善するための方法および組成物
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
EP2968220B1 (en) 2013-03-15 2021-05-05 Agenebio, Inc. Methods and compositions for improving cognitive function
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa

Also Published As

Publication number Publication date
ATE122037T1 (de) 1995-05-15
EP0381959B1 (en) 1995-05-03
KR900011759A (ko) 1990-08-02
DE69019007T2 (de) 1995-09-14
HU900127D0 (en) 1990-03-28
AU4798890A (en) 1990-07-26
NO174386B (no) 1994-01-17
HUT53607A (en) 1990-11-28
NO900234D0 (no) 1990-01-16
NO900234L (no) 1990-07-18
DE69019007D1 (de) 1995-06-08
NZ232112A (en) 1992-07-28
AU625157B2 (en) 1992-07-02
EP0381959A1 (en) 1990-08-16
PT92874A (pt) 1990-07-31
NO174386C (no) 1994-04-27
DK0381959T3 (da) 1995-09-04
IL93051A0 (en) 1990-11-05
JPH02229154A (ja) 1990-09-11
FI900231A0 (fi) 1990-01-16
CA2007732A1 (en) 1990-07-17
ES2071685T3 (es) 1995-07-01

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