DK0381959T3 - Cyclohexanacetamidderivater - Google Patents

Cyclohexanacetamidderivater

Info

Publication number
DK0381959T3
DK0381959T3 DK90100935.7T DK90100935T DK0381959T3 DK 0381959 T3 DK0381959 T3 DK 0381959T3 DK 90100935 T DK90100935 T DK 90100935T DK 0381959 T3 DK0381959 T3 DK 0381959T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
aryl
hydrogen
chem
acetamide derivatives
Prior art date
Application number
DK90100935.7T
Other languages
Danish (da)
English (en)
Inventor
Gary Lee Olson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0381959T3 publication Critical patent/DK0381959T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
DK90100935.7T 1989-01-17 1990-01-17 Cyclohexanacetamidderivater DK0381959T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29772689A 1989-01-17 1989-01-17
US37764389A 1989-07-10 1989-07-10

Publications (1)

Publication Number Publication Date
DK0381959T3 true DK0381959T3 (da) 1995-09-04

Family

ID=26970288

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90100935.7T DK0381959T3 (da) 1989-01-17 1990-01-17 Cyclohexanacetamidderivater

Country Status (16)

Country Link
EP (1) EP0381959B1 (xx)
JP (1) JPH02229154A (xx)
KR (1) KR900011759A (xx)
AT (1) ATE122037T1 (xx)
AU (1) AU625157B2 (xx)
CA (1) CA2007732A1 (xx)
DE (1) DE69019007T2 (xx)
DK (1) DK0381959T3 (xx)
ES (1) ES2071685T3 (xx)
FI (1) FI900231A0 (xx)
HU (1) HUT53607A (xx)
IL (1) IL93051A0 (xx)
MC (1) MC2081A1 (xx)
NO (1) NO174386C (xx)
NZ (1) NZ232112A (xx)
PT (1) PT92874A (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100395779B1 (ko) * 2001-05-25 2003-08-21 한국화학연구원 임의적으로 베타-위치가 치환된 알파-아릴알킬기의 제거를통해 3급 아미드 화합물로부터 2급 아미드 화합물을제조하는 방법
EP3260118B1 (en) 2008-10-16 2021-03-24 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
AU2014228512A1 (en) 2013-03-15 2015-10-01 Agenebio, Inc. Methods and compositions for improving cognitive function
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa

Also Published As

Publication number Publication date
NO174386B (no) 1994-01-17
HU900127D0 (en) 1990-03-28
FI900231A0 (fi) 1990-01-16
NO900234L (no) 1990-07-18
AU625157B2 (en) 1992-07-02
NZ232112A (en) 1992-07-28
ATE122037T1 (de) 1995-05-15
KR900011759A (ko) 1990-08-02
PT92874A (pt) 1990-07-31
JPH02229154A (ja) 1990-09-11
CA2007732A1 (en) 1990-07-17
NO174386C (no) 1994-04-27
EP0381959B1 (en) 1995-05-03
NO900234D0 (no) 1990-01-16
DE69019007T2 (de) 1995-09-14
HUT53607A (en) 1990-11-28
IL93051A0 (en) 1990-11-05
EP0381959A1 (en) 1990-08-16
DE69019007D1 (de) 1995-06-08
ES2071685T3 (es) 1995-07-01
MC2081A1 (fr) 1991-01-07
AU4798890A (en) 1990-07-26

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