IL92082A0 - Compositions comprising resiniferatoxin and their use - Google Patents

Compositions comprising resiniferatoxin and their use

Info

Publication number
IL92082A0
IL92082A0 IL92082A IL9208289A IL92082A0 IL 92082 A0 IL92082 A0 IL 92082A0 IL 92082 A IL92082 A IL 92082A IL 9208289 A IL9208289 A IL 9208289A IL 92082 A0 IL92082 A0 IL 92082A0
Authority
IL
Israel
Prior art keywords
resiniferatoxin
compositions
Prior art date
Application number
IL92082A
Other languages
English (en)
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of IL92082A0 publication Critical patent/IL92082A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
IL92082A 1988-10-24 1989-10-23 Compositions comprising resiniferatoxin and their use IL92082A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/261,627 US4939149A (en) 1988-10-24 1988-10-24 Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization

Publications (1)

Publication Number Publication Date
IL92082A0 true IL92082A0 (en) 1990-07-12

Family

ID=22994143

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92082A IL92082A0 (en) 1988-10-24 1989-10-23 Compositions comprising resiniferatoxin and their use

Country Status (8)

Country Link
US (2) US4939149A (fr)
EP (1) EP0439549B1 (fr)
JP (1) JPH0729919B2 (fr)
AU (1) AU619930B2 (fr)
CA (1) CA2001194C (fr)
DE (1) DE68910834T2 (fr)
IL (1) IL92082A0 (fr)
WO (1) WO1990004389A1 (fr)

Families Citing this family (72)

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AU5744490A (en) * 1989-05-15 1990-12-18 Afferon Corporation Composition and method for neural desensitization
US5021450A (en) * 1989-05-30 1991-06-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New class of compounds having a variable spectrum of activities for capsaicin-like responses, compositions and uses thereof
US5232684A (en) * 1990-06-29 1993-08-03 The United States Of America As Represented By The Department Of Health And Human Services Labelled resiniferatoxin, compositions thereof, and methods for using the same
WO1992003923A1 (fr) * 1990-08-29 1992-03-19 THE UNITED STATES OF AMERICA, represented by THE SCRETARY, UNITED STATES DEPARTMENT OF COMMERCE Graines pour oiseaux contenant de la capsaicine, ses derives ou ses analogues
US5629045A (en) * 1992-09-17 1997-05-13 Richard L. Veech Biodegradable nosiogenic agents for control of non-vertebrate pests
US6063381A (en) * 1993-05-19 2000-05-16 Staggs; Jeff J. Therapeutic uses of pungent botanicals and their related compounds
US6635659B1 (en) * 1995-03-20 2003-10-21 Arrie Kegler Topical formulation for arthritic symptoms treatment
US6248788B1 (en) 1996-11-06 2001-06-19 The Regents Of The University Of California Therapeutic method with capsaicin and capasicin analogs
US6239180B1 (en) 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
US5856361A (en) * 1996-04-23 1999-01-05 Medical Merchandising, Inc. Pain reliever and method of use
US5869533A (en) * 1996-04-23 1999-02-09 Holt; Stephen D. Non-irritating capsaicin formulations and applicators therefor
CA2264739C (fr) * 1996-09-05 2008-03-18 Research Development Foundation Inhibition du facteur de transcription nucleaire nf-kb par l'ester phenethylique d'acide cafeique, les derives de cet ester, la capsaicine (8-methyl-n-vanillyle-6-noneamide) et laresiniferatoxine
AU5460598A (en) * 1996-11-15 1998-06-03 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Pharmaceutical compositions containing vanilloid agonists in combination with vanilloid antagonists
DK0998288T4 (da) † 1997-03-13 2005-08-22 James N Campbell Sammensætninger indeholdende kapasaicin eller kapsaicinanaloge og et lokalbedövelsesmiddel
WO1999009970A1 (fr) * 1997-08-28 1999-03-04 Afferon Corporation Therapie contre l'incontinence urinaire
US6790207B2 (en) 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US20110071468A1 (en) * 1998-06-04 2011-03-24 Mederi Therapeutics, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US6802841B2 (en) * 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US6197823B1 (en) 1999-09-29 2001-03-06 Medical Merchandising, Inc. Pain reliever and method of use
US6348501B1 (en) 1999-09-29 2002-02-19 Medical Merchandising, Inc. Lotion compositions utilizing capsaicin
US6653352B2 (en) 1999-09-29 2003-11-25 Medical Merchandising, Inc. Pain reliever and method of use
EP1301484A2 (fr) * 2000-07-20 2003-04-16 Neurogen Corporation Ligands du recepteur de la capsicine
US20040146590A1 (en) * 2001-03-22 2004-07-29 Iadarola Michael J Molecular neurochirurgie for pain control administering locally capsaicin or resinferatoxin
US20060240125A1 (en) * 2005-04-21 2006-10-26 Astrup Arne V Composition for affecting weight loss
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
CN1627944A (zh) * 2002-01-17 2005-06-15 神经能质公司 取代的喹唑啉－4－基胺类似物作为辣椒辣素调节剂
US20040126430A1 (en) * 2002-09-05 2004-07-01 Angel Arturo J. Compositions and kits for the removal of irritating compounds from bodily surfaces
EP2422775A3 (fr) 2002-09-20 2012-04-18 Alpharma, Inc. Séquestration de sous-unité et compositions et procédés associés
US20040191338A1 (en) * 2002-12-18 2004-09-30 Algorx Administration of capsaicinoids
PT1605956E (pt) 2002-12-18 2016-03-09 Centrexion Therapeutics Corp Administração de capsaicinóides para o tratamento da osteoartrite
BRPI0409748A (pt) * 2003-04-08 2006-10-24 Algorx Pharmaceuticals Inc preparação e purificação de capsaicin sintetico
US20040224037A1 (en) * 2003-04-28 2004-11-11 Gonzalo Romero-Matos Devastating treatment against hiv/aids with capsaicin
CA2529984C (fr) 2003-06-26 2012-09-25 Isa Odidi Capsules contenant un inhibiteur de la pompe a protons comprenant des unites secondaires differemment structurees permettant une liberation retardee de l'ingredient actif
HUE037643T2 (hu) 2004-06-12 2018-09-28 Collegium Pharmaceutical Inc Visszaélésre nem alkalmas gyógyszerkészítmények
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
CA2596194A1 (fr) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Formulation a base de capsaicinoide en gel et utilisations afferentes
CA2594202C (fr) * 2004-12-28 2013-12-03 Mestex Ag Utilisation de la resiniferatoxine (rtx) pour produire un agent servant a traiter des douleurs articulaires, et procede d'administration de cet agent
NZ556261A (en) * 2005-01-28 2012-04-27 Adm Alliance Nutrition Inc Animal feed compositions capable of reducing the incidence of fescue toxicosis in mammas containing a coated or encapsulated capsaicin product and an adsorbant
WO2006107723A1 (fr) * 2005-04-01 2006-10-12 Neurogesx, Inc. Huiles de capsaicinoides et leurs methodes de conception et d'utilisation
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
BRPI0708716A2 (pt) * 2006-03-10 2011-06-07 Archer Daniels Midland Co métodos e composições para produtividade aumentada em animais
EP2007360B1 (fr) * 2006-04-03 2014-11-26 Isa Odidi Dispositif d'administration à libération commandée comprenant un enrobage organosol
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
CA2655835C (fr) 2006-06-19 2015-07-21 Alpharma, Inc. Compositions pharmaceutiques d'agonistes opioides resistants a l'abus
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
WO2008109026A1 (fr) * 2007-03-05 2008-09-12 Mt Cook Pharma Compositions pharmaceutiques pour traitement localisé d'un dysfonctionnement neurogénique
US8233976B2 (en) 2007-12-05 2012-07-31 The Invention Science Fund I, Llc System for transdermal chemical modulation of neural activity
US8165668B2 (en) 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8989858B2 (en) * 2007-12-05 2015-03-24 The Invention Science Fund I, Llc Implant system for chemical modulation of neural activity
US8180446B2 (en) * 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8165669B2 (en) 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US8170659B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc Method for thermal modulation of neural activity
US20090149799A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for chemical modulation of neural activity
US8170658B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US8195287B2 (en) 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US8987328B2 (en) 2008-10-30 2015-03-24 Trinity Laboratories, Inc. Esters of capsaicinoids as dietary supplements
US20100303932A1 (en) * 2009-05-28 2010-12-02 Baskaran Thyagarajan Method for Attenuating the Effects of Botulinum Toxin
WO2011044381A1 (fr) * 2009-10-07 2011-04-14 Inflasoothe, Inc. Composition, système et procédé pour soulager la douleur
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
US20130247383A1 (en) 2010-07-19 2013-09-26 3M Innovative Properties Company Hand tool with replaceable knife cartridge
DK2629610T3 (da) 2010-07-27 2017-11-20 Flex Pharma Inc Fremgangsmåder og sammensætninger til forebyggelse og lindring af muskelkramper og til rehabilitering fra neuromuskulær irritabilitet og træthed efter træning
DK2826467T3 (en) 2010-12-22 2017-10-16 Purdue Pharma Lp INCLUDED, MANIPULATION-PROPOSED SLOW-DELIVERY DOSAGE FORMS
CN107412173A (zh) 2010-12-23 2017-12-01 普渡制药公司 抗篡改固体口服剂型
AU2014215478B2 (en) 2013-02-05 2018-09-13 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
CA2910865C (fr) 2014-07-15 2016-11-29 Isa Odidi Compositions et methodes destines a reduire les surdoses
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
US11253493B2 (en) 2017-01-23 2022-02-22 Cliff-Cartwright Corporation Compositions and methods affecting exercise performance
US11707437B2 (en) 2019-07-12 2023-07-25 Board Of Trustees Of Southern Illinois University Topical formulations with resiniferatoxin nanoparticles and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2902506A1 (de) * 1979-01-23 1980-07-24 Deutsches Krebsforsch Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel
US4536404A (en) * 1983-06-16 1985-08-20 Dermatological Enterprises, Ltd. Method and composition for treating post-herpetic neuralgia
AU5744490A (en) * 1989-05-15 1990-12-18 Afferon Corporation Composition and method for neural desensitization

Also Published As

Publication number Publication date
DE68910834D1 (de) 1993-12-23
CA2001194A1 (fr) 1990-04-24
US5290816A (en) 1994-03-01
EP0439549A4 (en) 1991-12-04
EP0439549A1 (fr) 1991-08-07
JPH03504387A (ja) 1991-09-26
US4939149A (en) 1990-07-03
AU4624189A (en) 1990-05-14
JPH0729919B2 (ja) 1995-04-05
WO1990004389A1 (fr) 1990-05-03
CA2001194C (fr) 1995-12-05
EP0439549B1 (fr) 1993-11-18
AU619930B2 (en) 1992-02-06
DE68910834T2 (de) 1994-03-17

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Legal Events

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