IL92082A0 - Compositions comprising resiniferatoxin and their use - Google Patents

Compositions comprising resiniferatoxin and their use

Info

Publication number
IL92082A0
IL92082A0 IL92082A IL9208289A IL92082A0 IL 92082 A0 IL92082 A0 IL 92082A0 IL 92082 A IL92082 A IL 92082A IL 9208289 A IL9208289 A IL 9208289A IL 92082 A0 IL92082 A0 IL 92082A0
Authority
IL
Israel
Prior art keywords
resiniferatoxin
compositions
Prior art date
Application number
IL92082A
Other languages
English (en)
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of IL92082A0 publication Critical patent/IL92082A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
IL92082A 1988-10-24 1989-10-23 Compositions comprising resiniferatoxin and their use IL92082A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/261,627 US4939149A (en) 1988-10-24 1988-10-24 Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization

Publications (1)

Publication Number Publication Date
IL92082A0 true IL92082A0 (en) 1990-07-12

Family

ID=22994143

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92082A IL92082A0 (en) 1988-10-24 1989-10-23 Compositions comprising resiniferatoxin and their use

Country Status (8)

Country Link
US (2) US4939149A (xx)
EP (1) EP0439549B1 (xx)
JP (1) JPH0729919B2 (xx)
AU (1) AU619930B2 (xx)
CA (1) CA2001194C (xx)
DE (1) DE68910834T2 (xx)
IL (1) IL92082A0 (xx)
WO (1) WO1990004389A1 (xx)

Families Citing this family (72)

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AU5744490A (en) * 1989-05-15 1990-12-18 Afferon Corporation Composition and method for neural desensitization
US5021450A (en) * 1989-05-30 1991-06-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New class of compounds having a variable spectrum of activities for capsaicin-like responses, compositions and uses thereof
US5232684A (en) * 1990-06-29 1993-08-03 The United States Of America As Represented By The Department Of Health And Human Services Labelled resiniferatoxin, compositions thereof, and methods for using the same
ES2127729T3 (es) * 1990-08-29 1999-05-01 Us Health Alimento para aves que contiene capsaicina o sus derivados o analogos.
US5629045A (en) * 1992-09-17 1997-05-13 Richard L. Veech Biodegradable nosiogenic agents for control of non-vertebrate pests
US6063381A (en) * 1993-05-19 2000-05-16 Staggs; Jeff J. Therapeutic uses of pungent botanicals and their related compounds
US6635659B1 (en) * 1995-03-20 2003-10-21 Arrie Kegler Topical formulation for arthritic symptoms treatment
US6248788B1 (en) 1996-11-06 2001-06-19 The Regents Of The University Of California Therapeutic method with capsaicin and capasicin analogs
US6239180B1 (en) 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
US5869533A (en) * 1996-04-23 1999-02-09 Holt; Stephen D. Non-irritating capsaicin formulations and applicators therefor
US5856361A (en) * 1996-04-23 1999-01-05 Medical Merchandising, Inc. Pain reliever and method of use
EP0998275A4 (en) * 1996-09-05 2003-05-02 Res Dev Foundation INHIBITION OF THE NUCLEAR TRANSCRIPTION FACTOR NF-kappaB BY THE PHENETHYLIC ESTER OF CAFEIC ACID, DERIVATIVES OF THIS ESTER, CAPSAICIN (8-METHYL-N-VANILLYLE-6-NONEAMIDE) AND RESINIFERATOXIN
WO1998020867A1 (en) * 1996-11-15 1998-05-22 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Pharmaceutical compositions containing vanilloid agonists in combination with vanilloid antagonists
EP1201241B8 (en) † 1997-03-13 2010-10-27 James N. Campbell Compositions containing capsaicin or capsaicin analogues and an anesthetic
JP2001513551A (ja) * 1997-08-28 2001-09-04 アフェロン コーポレイション 尿失禁の治療
US6790207B2 (en) 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US6802841B2 (en) * 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US20110071468A1 (en) * 1998-06-04 2011-03-24 Mederi Therapeutics, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US6653352B2 (en) 1999-09-29 2003-11-25 Medical Merchandising, Inc. Pain reliever and method of use
US6197823B1 (en) 1999-09-29 2001-03-06 Medical Merchandising, Inc. Pain reliever and method of use
US6348501B1 (en) 1999-09-29 2002-02-19 Medical Merchandising, Inc. Lotion compositions utilizing capsaicin
MXPA03000458A (es) * 2000-07-20 2004-06-02 Neurogen Corp Ligandos receptores de capsaicina.
US20040146590A1 (en) * 2001-03-22 2004-07-29 Iadarola Michael J Molecular neurochirurgie for pain control administering locally capsaicin or resinferatoxin
US20060240125A1 (en) * 2005-04-21 2006-10-26 Astrup Arne V Composition for affecting weight loss
US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
MXPA04006882A (es) * 2002-01-17 2004-12-06 Neurogen Corp Analogos substituidos de quinazolin-4-ilamina como moduladores de receptores de capsaicina.
US20040126430A1 (en) 2002-09-05 2004-07-01 Angel Arturo J. Compositions and kits for the removal of irritating compounds from bodily surfaces
EP2422772A3 (en) 2002-09-20 2012-04-18 Alpharma, Inc. Sequestering subunit and related compositions and methods
AU2003301190A1 (en) * 2002-12-18 2004-07-14 Algorx Administration of capsaicinoids
CA2510181C (en) 2002-12-18 2011-03-08 Algorx Pharmaceuticals, Inc. Administration of capsaicinoids
NZ542887A (en) * 2003-04-08 2008-05-30 Algorx Pharmaceuticals Inc Preparation and purification of synthetic capsaicin
US20040224037A1 (en) * 2003-04-28 2004-11-11 Gonzalo Romero-Matos Devastating treatment against hiv/aids with capsaicin
WO2004112756A1 (en) * 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
SI1765292T1 (en) 2004-06-12 2018-04-30 Collegium Pharmaceutical, Inc. Formulations of medicines to discourage abuse
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1827405A2 (en) * 2004-11-24 2007-09-05 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
ES2533256T3 (es) * 2004-12-28 2015-04-08 Mestex Ag Uso de resiniferatoxina (RTX) para la fabricación de un medicamento para el tratamiento del dolor
US9241502B2 (en) * 2005-01-28 2016-01-26 Adm Alliance Nutrition Animal feed compositions capable of reducing the incidence of fescue toxicosis in mammals
PT1865941E (pt) * 2005-04-01 2011-01-05 Neurogesx Inc Óleos de capsaicinóides e métodos para a sua produção e utilização
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EP2007222B1 (en) * 2006-03-10 2017-05-03 Archer Daniels Midland Company Methods and compositions for increased productivity in animals
US9561188B2 (en) * 2006-04-03 2017-02-07 Intellipharmaceutics Corporation Controlled release delivery device comprising an organosol coat
US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
KR101486228B1 (ko) 2006-06-19 2015-01-26 알파마 파머슈티컬스 엘엘씨 약제학적 조성물
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
WO2008109026A1 (en) * 2007-03-05 2008-09-12 Mt Cook Pharma Pharmaceutical compositions for the localized treatment of neurogenic dysfunction
US8170658B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US8165668B2 (en) 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US20090149799A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for chemical modulation of neural activity
US8165669B2 (en) 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US8160695B2 (en) 2007-12-05 2012-04-17 The Invention Science Fund I, Llc System for chemical modulation of neural activity
US8195287B2 (en) 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US8233976B2 (en) 2007-12-05 2012-07-31 The Invention Science Fund I, Llc System for transdermal chemical modulation of neural activity
US8180446B2 (en) * 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8170660B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for thermal modulation of neural activity
US8987328B2 (en) 2008-10-30 2015-03-24 Trinity Laboratories, Inc. Esters of capsaicinoids as dietary supplements
US20100303932A1 (en) * 2009-05-28 2010-12-02 Baskaran Thyagarajan Method for Attenuating the Effects of Botulinum Toxin
US20110135627A1 (en) * 2009-10-07 2011-06-09 The Inflasoothe Group, Inc. Pain relief composition, system and method
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
WO2012012319A1 (en) 2010-07-19 2012-01-26 3M Innovative Properties Company Hand tool with replaceable knife cartridge
ES2647087T3 (es) 2010-07-27 2017-12-19 Flex Pharma, Inc. Métodos y composiciones para prevenir y aliviar los calambres musculares y para la recuperación de la irritabilidad neuromuscular y de la fatiga después del ejercicio
SG191288A1 (en) 2010-12-22 2013-07-31 Purdue Pharma Lp Encased tamper resistant controlled release dosage forms
JP5638151B2 (ja) 2010-12-23 2014-12-10 パーデュー、ファーマ、リミテッド、パートナーシップ 不正加工抵抗性の（ｔａｍｐｅｒｒｅｓｉｓｔａｎｔ）固形経口剤形
US9149533B2 (en) 2013-02-05 2015-10-06 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
CA2910865C (en) 2014-07-15 2016-11-29 Isa Odidi Compositions and methods for reducing overdose
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
WO2018136943A1 (en) 2017-01-23 2018-07-26 Flex Pharma, Inc. Compositions and methods affecting exercise performance
US11707437B2 (en) 2019-07-12 2023-07-25 Board Of Trustees Of Southern Illinois University Topical formulations with resiniferatoxin nanoparticles and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2902506A1 (de) * 1979-01-23 1980-07-24 Deutsches Krebsforsch Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel
US4536404A (en) * 1983-06-16 1985-08-20 Dermatological Enterprises, Ltd. Method and composition for treating post-herpetic neuralgia
AU5744490A (en) * 1989-05-15 1990-12-18 Afferon Corporation Composition and method for neural desensitization

Also Published As

Publication number Publication date
CA2001194C (en) 1995-12-05
US4939149A (en) 1990-07-03
WO1990004389A1 (en) 1990-05-03
DE68910834T2 (de) 1994-03-17
DE68910834D1 (de) 1993-12-23
AU4624189A (en) 1990-05-14
JPH0729919B2 (ja) 1995-04-05
AU619930B2 (en) 1992-02-06
EP0439549A1 (en) 1991-08-07
CA2001194A1 (en) 1990-04-24
JPH03504387A (ja) 1991-09-26
EP0439549B1 (en) 1993-11-18
US5290816A (en) 1994-03-01
EP0439549A4 (en) 1991-12-04

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Legal Events

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