IL91930A - Quinolinone derivatives, their preparation and their application in therapy - Google Patents

Quinolinone derivatives, their preparation and their application in therapy

Info

Publication number
IL91930A
IL91930A IL91930A IL9193089A IL91930A IL 91930 A IL91930 A IL 91930A IL 91930 A IL91930 A IL 91930A IL 9193089 A IL9193089 A IL 9193089A IL 91930 A IL91930 A IL 91930A
Authority
IL
Israel
Prior art keywords
therapy
application
preparation
quinolinone derivatives
alkyl radical
Prior art date
Application number
IL91930A
Other languages
English (en)
Other versions
IL91930A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL91930A0 publication Critical patent/IL91930A0/xx
Publication of IL91930A publication Critical patent/IL91930A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
IL91930A 1988-10-11 1989-10-10 Quinolinone derivatives, their preparation and their application in therapy IL91930A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8813324A FR2637591B1 (fr) 1988-10-11 1988-10-11 Derives de quinoleinone, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IL91930A0 IL91930A0 (en) 1990-06-10
IL91930A true IL91930A (en) 1993-08-18

Family

ID=9370884

Family Applications (1)

Application Number Title Priority Date Filing Date
IL91930A IL91930A (en) 1988-10-11 1989-10-10 Quinolinone derivatives, their preparation and their application in therapy

Country Status (20)

Country Link
US (1) US4983607A (pt)
EP (1) EP0364327B1 (pt)
JP (1) JPH02157267A (pt)
KR (1) KR900006317A (pt)
AT (1) ATE71617T1 (pt)
AU (1) AU619349B2 (pt)
CS (1) CS404891A3 (pt)
DE (1) DE68900717D1 (pt)
DK (1) DK500189A (pt)
ES (1) ES2037980T3 (pt)
FI (1) FI91748C (pt)
FR (1) FR2637591B1 (pt)
GR (1) GR3003921T3 (pt)
HU (1) HU204813B (pt)
IE (1) IE61830B1 (pt)
IL (1) IL91930A (pt)
NO (1) NO173058C (pt)
NZ (1) NZ230959A (pt)
PT (1) PT91939B (pt)
ZA (1) ZA897672B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635105B1 (fr) * 1988-08-03 1991-01-25 Synthelabo Derives de piperazine et leur procede de preparation
US5457099A (en) * 1992-07-02 1995-10-10 Sawai Pharmaceutical Co., Ltd. Carbostyril derivatives and antiallergic agent
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
WO1994020471A1 (en) * 1993-03-05 1994-09-15 Merck Sharp & Dohme Limited Quinolone derivatives as dopamine d4 ligands
WO1994021619A1 (en) * 1993-03-16 1994-09-29 Pfizer Inc. Naphthalene derivatives
FR2737723B1 (fr) * 1995-08-09 1997-09-05 Synthelabo Derives de 1-(2-(1h-inden-3-yl)ethyl)-4-(naphtalen-1-yl)- piperazine, leur preparation et leur application en therapeutique
FR2738823B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique
FR2761071B1 (fr) * 1997-03-20 1999-12-03 Synthelabo Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
FR2761067B1 (fr) * 1997-03-20 1999-04-23 Synthelabo Derives de quinolein-2-(1h)-one, leur preparation et leur application en therapeutique
US6562837B1 (en) * 1998-10-21 2003-05-13 Korea Institute Of Science & Technology Use of tetrahydroisoquinoline compounds for the treatment of septicemia
NZ535616A (en) 2000-11-07 2006-03-31 Novartis Ag Indolymaleimide derivatives as protein kinase c inhibitors
US7053092B2 (en) * 2001-01-29 2006-05-30 Otsuka Pharmaceutical Co., Ltd. 5-HT1a receptor subtype agonist
US8703772B2 (en) 2001-09-25 2014-04-22 Otsuka Pharmaceutical Co., Ltd. Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
TW200803855A (en) * 2006-02-24 2008-01-16 Kalypsys Inc Quinolones useful as inducible nitric oxide synthase inhibitors
NZ590041A (en) * 2008-05-20 2012-11-30 Astrazeneca Ab Method of treating anxious major depressive disorder
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54128588A (en) * 1978-03-29 1979-10-05 Dainippon Pharmaceut Co Ltd Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
US4284768A (en) * 1980-07-02 1981-08-18 American Home Products Corporation 1,2-Dihydro-4-amino-2-oxo-3-quinoline-carboxylic acid derivatives
GB8827189D0 (en) * 1988-11-21 1988-12-29 Fujisawa Pharmaceutical Co 2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same

Also Published As

Publication number Publication date
NZ230959A (en) 1990-12-21
HU204813B (en) 1992-02-28
DK500189A (da) 1990-04-12
DE68900717D1 (de) 1992-02-27
GR3003921T3 (pt) 1993-03-16
IL91930A0 (en) 1990-06-10
IE61830B1 (en) 1994-11-30
FI91748B (fi) 1994-04-29
US4983607A (en) 1991-01-08
EP0364327A1 (fr) 1990-04-18
ZA897672B (en) 1990-07-25
NO173058B (no) 1993-07-12
AU4275089A (en) 1990-04-26
NO894036D0 (no) 1989-10-10
FR2637591B1 (fr) 1992-10-23
PT91939A (pt) 1990-04-30
KR900006317A (ko) 1990-05-07
ATE71617T1 (de) 1992-02-15
AU619349B2 (en) 1992-01-23
IE893265L (en) 1990-04-11
HUT51612A (en) 1990-05-28
NO173058C (no) 1993-10-20
FI91748C (fi) 1994-08-10
ES2037980T3 (es) 1993-07-01
JPH02157267A (ja) 1990-06-18
FR2637591A1 (fr) 1990-04-13
EP0364327B1 (fr) 1992-01-15
CS404891A3 (en) 1992-04-15
FI894803A (fi) 1990-04-12
NO894036L (no) 1990-04-17
PT91939B (pt) 1995-05-31
DK500189D0 (da) 1989-10-10
HU895268D0 (en) 1990-01-28
FI894803A0 (fi) 1989-10-10

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force