DE68900717D1 - Chinolinonderivate, ihre herstellung und ihre verwendung als arzneimittel. - Google Patents

Chinolinonderivate, ihre herstellung und ihre verwendung als arzneimittel.

Info

Publication number
DE68900717D1
DE68900717D1 DE8989402700T DE68900717T DE68900717D1 DE 68900717 D1 DE68900717 D1 DE 68900717D1 DE 8989402700 T DE8989402700 T DE 8989402700T DE 68900717 T DE68900717 T DE 68900717T DE 68900717 D1 DE68900717 D1 DE 68900717D1
Authority
DE
Germany
Prior art keywords
production
medicinal products
alkyl radical
chinoline derivatives
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989402700T
Other languages
English (en)
Inventor
Philippe Manoury
Daniel Obitz
Michel Peynot
Jonathan Frost
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of DE68900717D1 publication Critical patent/DE68900717D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE8989402700T 1988-10-11 1989-10-02 Chinolinonderivate, ihre herstellung und ihre verwendung als arzneimittel. Expired - Lifetime DE68900717D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8813324A FR2637591B1 (fr) 1988-10-11 1988-10-11 Derives de quinoleinone, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
DE68900717D1 true DE68900717D1 (de) 1992-02-27

Family

ID=9370884

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989402700T Expired - Lifetime DE68900717D1 (de) 1988-10-11 1989-10-02 Chinolinonderivate, ihre herstellung und ihre verwendung als arzneimittel.

Country Status (20)

Country Link
US (1) US4983607A (de)
EP (1) EP0364327B1 (de)
JP (1) JPH02157267A (de)
KR (1) KR900006317A (de)
AT (1) ATE71617T1 (de)
AU (1) AU619349B2 (de)
CS (1) CS404891A3 (de)
DE (1) DE68900717D1 (de)
DK (1) DK500189A (de)
ES (1) ES2037980T3 (de)
FI (1) FI91748C (de)
FR (1) FR2637591B1 (de)
GR (1) GR3003921T3 (de)
HU (1) HU204813B (de)
IE (1) IE61830B1 (de)
IL (1) IL91930A (de)
NO (1) NO173058C (de)
NZ (1) NZ230959A (de)
PT (1) PT91939B (de)
ZA (1) ZA897672B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635105B1 (fr) * 1988-08-03 1991-01-25 Synthelabo Derives de piperazine et leur procede de preparation
US5457099A (en) * 1992-07-02 1995-10-10 Sawai Pharmaceutical Co., Ltd. Carbostyril derivatives and antiallergic agent
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
JPH08508466A (ja) * 1993-03-05 1996-09-10 メルク シヤープ エンド ドーム リミテツド ドーパミンｄ４リガンドとしてのキノロン誘導体
AU6391894A (en) * 1993-03-16 1994-10-11 Pfizer Inc. Naphthalene derivatives
FR2737723B1 (fr) * 1995-08-09 1997-09-05 Synthelabo Derives de 1-(2-(1h-inden-3-yl)ethyl)-4-(naphtalen-1-yl)- piperazine, leur preparation et leur application en therapeutique
FR2738823B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique
FR2761071B1 (fr) * 1997-03-20 1999-12-03 Synthelabo Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
FR2761067B1 (fr) * 1997-03-20 1999-04-23 Synthelabo Derives de quinolein-2-(1h)-one, leur preparation et leur application en therapeutique
US6562837B1 (en) * 1998-10-21 2003-05-13 Korea Institute Of Science & Technology Use of tetrahydroisoquinoline compounds for the treatment of septicemia
DE60140201D1 (en) 2000-11-07 2009-11-26 Novartis Ag Indolylmaleimidderivative als proteinkinase-c-inhibitoren
US7053092B2 (en) 2001-01-29 2006-05-30 Otsuka Pharmaceutical Co., Ltd. 5-HT1a receptor subtype agonist
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
US8703772B2 (en) 2001-09-25 2014-04-22 Otsuka Pharmaceutical Co., Ltd. Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
TW200803855A (en) * 2006-02-24 2008-01-16 Kalypsys Inc Quinolones useful as inducible nitric oxide synthase inhibitors
EP2296657A4 (de) * 2008-05-20 2011-12-14 Astrazeneca Ab Verfahren zur behandlung von schwerer depression mit angstzuständen
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54128588A (en) * 1978-03-29 1979-10-05 Dainippon Pharmaceut Co Ltd Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
US4284768A (en) * 1980-07-02 1981-08-18 American Home Products Corporation 1,2-Dihydro-4-amino-2-oxo-3-quinoline-carboxylic acid derivatives
GB8827189D0 (en) * 1988-11-21 1988-12-29 Fujisawa Pharmaceutical Co 2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same

Also Published As

Publication number Publication date
DK500189D0 (da) 1989-10-10
ZA897672B (en) 1990-07-25
AU4275089A (en) 1990-04-26
IE893265L (en) 1990-04-11
US4983607A (en) 1991-01-08
HUT51612A (en) 1990-05-28
FI894803A0 (fi) 1989-10-10
ATE71617T1 (de) 1992-02-15
IL91930A0 (en) 1990-06-10
DK500189A (da) 1990-04-12
KR900006317A (ko) 1990-05-07
NO894036D0 (no) 1989-10-10
PT91939A (pt) 1990-04-30
NZ230959A (en) 1990-12-21
FI91748C (fi) 1994-08-10
FR2637591B1 (fr) 1992-10-23
EP0364327A1 (de) 1990-04-18
IE61830B1 (en) 1994-11-30
FI894803A (fi) 1990-04-12
FR2637591A1 (fr) 1990-04-13
NO894036L (no) 1990-04-17
PT91939B (pt) 1995-05-31
HU895268D0 (en) 1990-01-28
NO173058B (no) 1993-07-12
GR3003921T3 (de) 1993-03-16
EP0364327B1 (de) 1992-01-15
HU204813B (en) 1992-02-28
CS404891A3 (en) 1992-04-15
ES2037980T3 (es) 1993-07-01
AU619349B2 (en) 1992-01-23
NO173058C (no) 1993-10-20
IL91930A (en) 1993-08-18
FI91748B (fi) 1994-04-29
JPH02157267A (ja) 1990-06-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8339 Ceased/non-payment of the annual fee